phrog_10100 is made of 10 protein sequences and is annotated as "HTH DNA binding protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
65.8 70 65


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
JX976549_p33 AFV51517.1 putative binding HTH domain or homeodomain-like protein JX976549 Acinetobacter phage IME-AB2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Obolenskvirus; Acinetobacter virus AB2.
MF346584_p61 ASJ78932.1 hypothetical protein MF346584 Acinetobacter phage AbP2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Obolenskvirus; Acinetobacter virus AbP2.
HM368260_p36 ADO14407.1 AB1gp36 HM368260 Acinetobacter phage AB1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Obolenskvirus; Acinetobacter virus AB1.
NC_028855_p43 YP_009203562.1 hypothetical protein NC_028855 Acinetobacter phage YMC11/12/R2315 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Obolenskvirus; unclassified Obolenskvirus.
NC_017984_p10 YP_006383760.1 hypothetical protein NC_017984 Acinetobacter bacteriophage AP22 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Obolenskvirus.
NC_031117_p71 YP_009291943.1 hypothetical protein NC_031117 Acinetobacter phage LZ35 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Obolenskvirus; Acinetobacter virus LZ35.
KY670595_p57 ARB06798.1 fis family transcriptional regulator KY670595 Acinetobacter phage WCHABP12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Obolenskvirus; Acinetobacter virus WCHABP12.
NC_024785_p5 YP_009055426.1 hypothetical protein NC_024785 Acinetobacter phage YMC-13-01-C62 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Obolenskvirus.
KY829116_p52 ARQ94773.1 fis family transcriptional regulator KY829116 Acinetobacter phage WCHABP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Obolenskvirus; Acinetobacter virus WCHABP1.
p138349 no NCBI prot ID no annotation VI_09249 Gammaproteobacteria_gi_452736964_0_41957 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_11107 9 no annotation unknown function 8 1.57E-43 33.92
phrog_2315 65 no annotation unknown function 5 4.33E-21 11.48
phrog_26844 3 no annotation unknown function 2 9.38E-15 5.15

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_13024 no annotation unknown function 98.9 9.7E-13 13-63 / 25-75
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 94.1 0.0052 40-62 / 24-46
phrog_2119 no annotation unknown function 94.3 0.0041 39-63 / 27-51
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.5 0.0032 29-62 / 23-60
phrog_268 no annotation unknown function 97.4 5.4E-07 31-60 / 8-37
phrog_33852 no annotation unknown function 91.8 0.029 28-57 / 8-37
phrog_35933 no annotation unknown function 94.4 0.0035 31-62 / 21-52
phrog_35 transcriptional repressor transcription regulation 92.8 0.015 37-62 / 11-36
phrog_3736 no annotation unknown function 90.9 0.044 38-63 / 16-41
phrog_409 transcriptional regulator transcription regulation 92.0 0.025 35-60 / 6-31
phrog_66 excisionase and transcriptional regulator integration and excision 92.7 0.017 41-61 / 11-31

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF08822.10 Protein of unknown function (DUF1804) 1.3E-06 33-69 / 11-47
PF13412.5 Winged helix-turn-helix DNA-binding 2.1E-06 41-69 / 17-45
PF13011.5 leucine-zipper of insertion element IS481 3.2E-06 39-69 / 22-52
PF05344.10 Domain of Unknown Function (DUF746) 3.7E-06 40-68 / 11-39
PF09607.9 Brinker DNA-binding domain 4E-06 42-68 / 26-52
PF06627.10 Protein of unknown function (DUF1153) 5.2E-06 30-69 / 35-74
PF10668.8 Phage terminase small subunit 7E-06 41-68 / 22-49
PF16087.4 Domain of unknown function (DUF4817) 7.1E-06 38-69 / 13-52
PF06322.10 Phage NinH protein 7.5E-06 40-68 / 15-43
PF00292.17 'Paired box' domain 8.9E-06 39-68 / 31-60
PF02319.19 E2F/DP family winged-helix DNA-binding domain 1.1E-05 40-69 / 22-51
PF07141.10 Putative bacteriophage terminase small subunit 1.2E-05 40-67 / 30-57
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 1.3E-05 41-69 / 13-41
PF04936.11 Protein of unknown function (DUF658) 0.0019 40-66 / 87-113
PF02954.18 Bacterial regulatory protein, Fis family 1.8E-05 41-64 / 16-39
PF13309.5 HTH domain 1.8E-05 42-63 / 42-63
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 3.4E-05 40-67 / 18-45
PF04218.12 CENP-B N-terminal DNA-binding domain 3.8E-05 42-67 / 24-49
PF13404.5 AsnC-type helix-turn-helix domain 4.3E-05 41-65 / 17-41
PF08222.10 CodY helix-turn-helix domain 4.3E-05 42-69 / 5-32
PF13518.5 Helix-turn-helix domain 4.8E-05 42-69 / 12-39
PF01710.15 Transposase 4.8E-05 40-67 / 17-44
PF01022.19 Bacterial regulatory protein, arsR family 5E-05 41-69 / 16-44
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 5.2E-05 41-70 / 22-51
PF07750.10 GcrA cell cycle regulator 5.7E-05 39-67 / 16-45
PF05225.15 helix-turn-helix, Psq domain 6.2E-05 40-67 / 15-43
PF01527.19 Transposase 6.4E-05 39-66 / 19-46
PF05331.10 Protein of unknown function (DUF742) 6.1E-05 40-69 / 52-81
PF04492.12 Bacteriophage replication protein O 7.4E-05 41-70 / 49-78
PF09012.9 FeoC like transcriptional regulator 7.6E-05 41-69 / 14-42
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 8.3E-05 40-69 / 26-55
PF13556.5 PucR C-terminal helix-turn-helix domain 9.2E-05 41-67 / 12-38
PF02042.14 RWP-RK domain 0.0001 41-67 / 12-38
PF12802.6 MarR family 0.0001 42-69 / 22-49
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00011 39-69 / 16-46
PF08535.9 KorB domain 0.00011 42-67 / 4-29
PF08765.10 Mor transcription activator family 0.00012 41-67 / 72-98
PF16221.4 winged helix-turn-helix 0.00012 41-70 / 46-75
PF12759.6 InsA C-terminal domain 0.00012 40-65 / 20-45
PF05584.10 Sulfolobus plasmid regulatory protein 0.00014 40-69 / 17-46
PF00325.19 Bacterial regulatory proteins, crp family 0.00015 44-69 / 5-30
PF13411.5 MerR HTH family regulatory protein 0.00015 44-65 / 3-24
PF01047.21 MarR family 0.00016 42-69 / 18-45
PF13463.5 Winged helix DNA-binding domain 0.00015 42-69 / 18-45
PF01381.21 Helix-turn-helix 0.00017 40-64 / 8-32
PF14493.5 Helix-turn-helix domain 0.00018 40-69 / 11-40
PF17443.1 Uncharacterized protein pXO2-72 0.00018 42-62 / 9-29
PF13601.5 Winged helix DNA-binding domain 0.00022 42-69 / 15-42
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.00028 43-65 / 28-50
PF11427.7 Tc3 transposase 0.00029 41-69 / 20-48
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.00029 42-69 / 23-50
PF09824.8 ArsR transcriptional regulator 0.00027 30-70 / 19-57
PF00356.20 Bacterial regulatory proteins, lacI family 0.00031 44-64 / 2-22
PF04552.12 Sigma-54, DNA binding domain 0.0003 39-66 / 46-73
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.0003 41-64 / 107-130
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.00032 40-63 / 23-46
PF10654.8 Protein of unknown function (DUF2481) 0.00032 39-65 / 78-104
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.00034 40-67 / 54-81
PF07453.12 NUMOD1 domain 0.00035 42-61 / 20-39
PF00376.22 MerR family regulatory protein 0.00038 45-64 / 3-22
PF01418.16 Helix-turn-helix domain, rpiR family 0.00039 41-69 / 34-62
PF05043.12 Mga helix-turn-helix domain 0.00039 40-67 / 29-56
PF06163.10 Bacterial protein of unknown function (DUF977) 0.00046 40-69 / 25-54
PF04182.11 B-block binding subunit of TFIIIC 0.00047 42-69 / 19-46
PF06806.11 Putative excisionase (DUF1233) 0.00047 42-63 / 10-31
PF13591.5 MerR HTH family regulatory protein 0.00048 43-64 / 2-23
PF09339.9 IclR helix-turn-helix domain 0.0005 42-69 / 19-46
PF13551.5 Winged helix-turn helix 0.00051 42-69 / 12-39
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00052 43-68 / 13-38
PF15978.4 Tn7-like transposition protein D 0.00052 40-67 / 202-229
PF02295.16 Adenosine deaminase z-alpha domain 0.00054 41-69 / 18-47
PF16677.4 DNA-packaging protein gp3 0.00054 40-65 / 28-53
PF00392.20 Bacterial regulatory proteins, gntR family 0.00056 43-69 / 26-52
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.00055 43-65 / 53-75
PF14947.5 Winged helix-turn-helix 0.00057 42-69 / 17-44
PF02082.19 Transcriptional regulator 0.00063 42-69 / 25-52
PF07900.10 Protein of unknown function (DUF1670) 0.00065 40-70 / 94-124
PF02796.14 Helix-turn-helix domain of resolvase 0.0007 41-64 / 21-44
PF15977.4 Winged helix-turn-helix DNA binding 0.00072 42-69 / 24-51
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.00076 43-63 / 5-25
PF05732.10 Firmicute plasmid replication protein (RepL) 0.00081 41-70 / 75-104
PF08279.11 HTH domain 0.00087 41-69 / 15-43
PF10743.8 Regulatory phage protein cox 0.00088 42-64 / 12-34
PF01371.18 Trp repressor protein 0.00099 39-67 / 46-74
PF13413.5 Helix-turn-helix domain 0.001 41-64 / 9-32
PF07638.10 ECF sigma factor 0.001 40-66 / 148-174
PF02002.16 TFIIE alpha subunit 0.0011 40-69 / 25-54
PF07278.10 Protein of unknown function (DUF1441) 0.0011 42-64 / 2-24
PF04703.11 FaeA-like protein 0.0011 42-69 / 15-42
PF11313.7 Protein of unknown function (DUF3116) 0.0011 50-70 / 36-56
PF09904.8 Winged helix-turn helix 0.0012 42-69 / 22-49
PF12116.7 Stage III sporulation protein D 0.0012 40-65 / 18-43
PF07037.10 Putative transcription regulator (DUF1323) 0.0012 43-64 / 2-23
PF09035.9 Excisionase from transposon Tn916 0.0013 41-63 / 15-37
PF09182.9 Bacterial purine repressor, N-terminal 0.0013 41-67 / 20-46
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0016 42-69 / 22-49
PF13936.5 Helix-turn-helix domain 0.0017 41-64 / 20-43
PF14502.5 Helix-turn-helix domain 0.0017 44-68 / 9-33
PF11242.7 Protein of unknown function (DUF2774) 0.0017 41-67 / 14-40
PF12728.6 Helix-turn-helix domain 0.0018 43-63 / 3-24
PF06969.15 HemN C-terminal domain 0.0018 41-69 / 20-49
PF00440.22 Bacterial regulatory proteins, tetR family 0.002 42-66 / 16-40
PF08281.11 Sigma-70, region 4 0.002 40-66 / 25-51
PF12964.6 Protein of unknown function (DUF3853) 0.002 42-64 / 46-68
PF13384.5 Homeodomain-like domain 0.0022 41-65 / 17-41
PF16509.4 TrfB plasmid transcriptional repressor 0.0026 40-66 / 30-56
PF07471.11 Phage DNA packaging protein Nu1 0.0025 42-64 / 3-25
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.0027 43-69 / 26-52
PF05158.11 RNA polymerase Rpc34 subunit 0.0026 40-70 / 107-137
PF13545.5 Crp-like helix-turn-helix domain 0.0027 42-69 / 28-55
PF07506.10 RepB plasmid partitioning protein 0.0026 40-65 / 20-45
PF04967.11 HTH DNA binding domain 0.003 43-66 / 25-48
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0031 42-69 / 18-45
PF07848.11 PaaX-like protein 0.0033 42-69 / 21-51
PF08220.11 DeoR-like helix-turn-helix domain 0.0035 42-69 / 15-42
PF09202.10 Rio2, N-terminal 0.0035 42-69 / 25-52
PF06971.12 Putative DNA-binding protein N-terminus 0.0038 41-62 / 27-48
PF13022.5 Helix-turn-helix of insertion element transposase 0.0041 42-64 / 26-48
PF07618.10 Protein of unknown function (DUF1580) 0.0042 47-65 / 8-26
PF08280.10 M protein trans-acting positive regulator (MGA) HTH domain 0.0048 41-66 / 20-45
PF04545.15 Sigma-70, region 4 0.0058 40-65 / 23-48
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.0063 43-63 / 13-33
PF11972.7 HTH DNA binding domain 0.0073 42-65 / 14-37
PF16864.4 Dimerisation domain 0.0077 41-69 / 32-60
PF00196.18 Bacterial regulatory proteins, luxR family 0.0086 41-67 / 17-43
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 0.008 38-63 / 20-45
PF05339.10 Protein of unknown function (DUF739) 0.0088 42-63 / 17-38
PF04079.15 Segregation and condensation complex subunit ScpB 0.009 38-69 / 94-122
PF06413.10 Neugrin 0.009 42-64 / 30-52
PF03297.14 S25 ribosomal protein 0.0095 42-69 / 57-84

Annotations of the NCBI proteins of this PHROG


6:hypothetical protein 2:fis family transcriptional regulator 1:binding HTH domain or homeodomain-like protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005737 cytoplasm
GO:0051304 chromosome separation
GO:0006355 regulation of transcription, DNA-templated
GO:0051775 response to redox state
GO:0006352 DNA-templated transcription, initiation
GO:0003723 RNA binding
GO:0019069 viral capsid assembly
GO:0005524 ATP binding
GO:0006276 plasmid maintenance
GO:0004803 transposase activity
GO:0043565 sequence-specific DNA binding
GO:0005666 DNA-directed RNA polymerase III complex
GO:0004674 protein serine/threonine kinase activity
GO:0006383 transcription by RNA polymerase III
GO:0009289 pilus
GO:0005622 intracellular
GO:0006260 DNA replication
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex
GO:0016987 sigma factor activity
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity
GO:0003700 DNA binding transcription factor activity
GO:0006310 DNA recombination
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0003677 DNA binding
GO:0006468 protein phosphorylation

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