phrog_10378 is made of 10 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
288.6 320 296


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_001416_p28 NP_040607.1 ea31 NC_001416 Escherichia virus Lambda Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus.
p337986 no NCBI prot ID no annotation VI_03719 Gammaproteobacteria_gi_510921654_180464_201856 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p73764 no NCBI prot ID no annotation VI_02776 Gammaproteobacteria_gi_476381109_1234427_1283335 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
NC_019723_p25 YP_007112563.1 Ea31 protein NC_019723 Enterobacteria phage HK630 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus.
NC_019711_p28 YP_007111802.1 Ea31 protein NC_019711 Enterobacteria phage HK629 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus.
p152768 no NCBI prot ID no annotation VI_02355 Gammaproteobacteria_gi_476381174_175766_216344 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p188044 no NCBI prot ID no annotation VI_03674 Gammaproteobacteria_gi_510911666_556741_594193 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; Escherichia virus HK630; Escherichia phage HK630.
p226714 no NCBI prot ID no annotation VI_06827 Gammaproteobacteria_gi_415841233 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p189389 no NCBI prot ID no annotation VI_02895 Gammaproteobacteria_gi_425299628_29_37315 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p247817 no NCBI prot ID no annotation VI_01507 Gammaproteobacteria_gi_545232945_16748_48793 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_8066 14 no annotation unknown function 10 3.61E-54 44.56
phrog_19262 4 no annotation unknown function 2 9.42E-15 5.15

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 96.0 0.00016 97-154 / 93-154
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 5E-05 99-150 / 25-79
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 91.7 0.03 102-153 / 143-200
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.3E-05 99-183 / 10-86
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 95.8 0.00028 98-151 / 55-111
phrog_16016 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.8E-06 100-170 / 43-114
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 94.5 0.003 78-151 / 58-128
phrog_16986 no annotation unknown function 93.2 0.011 99-158 / 14-73
phrog_18937 no annotation unknown function 98.9 7E-13 77-221 / 71-206
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 6.1E-05 100-151 / 11-72
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 9.5E-07 99-151 / 29-78
phrog_2914 endonuclease VII DNA, RNA and nucleotide metabolism 90.8 0.047 97-151 / 30-79
phrog_33554 HNH endonuclease DNA, RNA and nucleotide metabolism 93.3 0.01 104-151 / 18-73
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.6E-05 101-156 / 24-86
phrog_36683 no annotation unknown function 94.4 0.0034 71-226 / 30-183
phrog_4581 terminase small subunit head and packaging 94.7 0.0023 79-150 / 27-105
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.002 101-151 / 19-69
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 96.0 0.00016 99-151 / 44-97
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 94.2 0.0042 101-150 / 2-54
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 90.2 0.06 96-185 / 32-109
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00036 88-151 / 49-110
phrog_8644 no annotation unknown function 96.7 1.5E-05 104-236 / 127-267
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 93.9 0.006 102-151 / 107-153
phrog_9443 HNH endonuclease DNA, RNA and nucleotide metabolism 90.1 0.062 104-166 / 97-155

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05766.11 Bacteriophage Lambda NinG protein 2E-09 91-216 / 72-180
PF13395.5 HNH endonuclease 2E-06 108-153 / 1-51
PF05315.10 ICEA Protein 3.5E-06 89-152 / 77-149
PF01844.22 HNH endonuclease 4.8E-06 108-151 / 1-46
PF14279.5 HNH endonuclease 2.4E-05 108-153 / 1-45
PF13391.5 HNH endonuclease 5.1E-05 108-154 / 1-46
PF06147.10 Protein of unknown function (DUF968) 0.00014 104-153 / 126-174
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.00029 105-154 / 253-297
PF16784.4 Putative HNHc nuclease 0.0031 103-152 / 121-170

Annotations of the NCBI proteins of this PHROG


3:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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