phrog_10514 is made of 10 protein sequences and is annotated as "DNA primase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
746.9 916 753


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF185731_p54 ASX99282.1 DNA primase MF185731 Arthrobacter phage Molivia Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Amigovirus; Arthrobacteria virus Molivia.
NC_013698_p44 YP_003359135.1 hypothetical protein NC_013698 Clavibacter phage CMP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cimpunavirus; Clavibacter virus CMP1.
NC_023549_p22 YP_009004234.1 hypothetical protein NC_023549 Clavibacter phage CN1A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cinunavirus; Clavibacter virus CN1A.
KU160647_p51 ALY09115.1 DNA primase KU160647 Arthrobacter phage Gorgeous Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Amigovirus; unclassified Amigovirus.
KU160663_p53 ALY10134.1 DNA primase KU160663 Arthrobacter phage Rings Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Amigovirus; unclassified Amigovirus.
KU160638_p52 ALY08407.1 DNA primase KU160638 Arthrobacter phage Amigo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Amigovirus; Arthrobacter virus Amigo.
KR093635_p3 AKI27472.1 hypothetical protein KR093635 Moraxella phage Mcat11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KR093647_p34 AKI27995.1 hypothetical protein KR093647 Moraxella phage Mcat23 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KR093641_p39 AKI27725.1 virulence associated E family protein KR093641 Moraxella phage Mcat17 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KR093634_p4 AKI27440.1 hypothetical protein KR093634 Moraxella phage Mcat10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_664 211 DNA binding protein DNA, RNA and nucleotide metabolism 5 5.97E-18 8.35
phrog_378 333 single strand DNA binding protein DNA, RNA and nucleotide metabolism 4 1.04E-13 4.11
phrog_190 562 Holliday junction resolvase DNA, RNA and nucleotide metabolism 4 1.43E-12 2.96

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10371 DNA helicase DNA, RNA and nucleotide metabolism 96.6 2.2E-05 319-717 / 259-663
phrog_14296 DNA primase DNA, RNA and nucleotide metabolism 97.8 2.9E-08 332-693 / 3-352
phrog_2135 DNA primase DNA, RNA and nucleotide metabolism 97.9 2.1E-08 372-654 / 53-381
phrog_2373 DNA helicase DNA, RNA and nucleotide metabolism 98.0 7.8E-09 326-717 / 57-512
phrog_2478 DNA polymerase/primase DNA, RNA and nucleotide metabolism 96.7 1.4E-05 2-195 / 2-240
phrog_25314 no annotation unknown function 94.3 0.0039 69-264 / 95-332
phrog_25777 DNA primase DNA, RNA and nucleotide metabolism 96.8 8.9E-06 331-654 / 425-812
phrog_3022 DNA primase DNA, RNA and nucleotide metabolism 100.0 2.5E-35 313-724 / 323-759
phrog_3123 no annotation unknown function 99.6 1.7E-19 5-289 / 6-263
phrog_33132 DNA primase DNA, RNA and nucleotide metabolism 94.4 0.0033 373-681 / 64-397
phrog_4861 DNA primase DNA, RNA and nucleotide metabolism 95.3 0.00094 82-190 / 114-230
phrog_5311 helicase DNA, RNA and nucleotide metabolism 99.4 2.3E-17 333-733 / 311-722

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF16793.4 RepB DNA-primase from phage plasmid 5.1E-16 58-208 / 24-170
PF00493.22 MCM2/3/5 family 1.7E-14 362-686 / 8-320
PF08273.11 Zinc-binding domain of primase-helicase 1.1E-09 287-313 / 2-27
PF13337.5 Putative ATP-dependent Lon protease 6.9E-08 643-687 / 390-435
PF01078.20 Magnesium chelatase, subunit ChlI 3E-06 415-437 / 24-46
PF13654.5 AAA domain 0.0012 379-438 / 3-49
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 8.5E-06 378-435 / 19-67
PF12775.6 P-loop containing dynein motor region D3 1.3E-05 415-437 / 35-57
PF05673.12 Protein of unknown function (DUF815) 1.6E-05 378-481 / 29-121
PF06431.10 Polyomavirus large T antigen C-terminus 2.3E-05 413-562 / 155-286
PF00158.25 Sigma-54 interaction domain 4E-05 414-437 / 23-46
PF13148.5 Protein of unknown function (DUF3987) 4.8E-05 612-689 / 282-361
PF05272.10 Virulence-associated protein E 9.3E-05 412-436 / 58-82
PF13177.5 DNA polymerase III, delta subunit 0.0001 415-437 / 21-43
PF00308.17 Bacterial dnaA protein 9.8E-05 415-437 / 35-57
PF08298.10 PrkA AAA domain 0.00012 379-437 / 59-109
PF07726.10 ATPase family associated with various cellular activities (AAA) 0.00012 415-436 / 1-22
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 0.00013 414-481 / 33-97
PF00519.16 Papillomavirus helicase 0.00015 414-481 / 263-320
PF00910.21 RNA helicase 0.00034 416-437 / 1-22
PF05621.10 Bacterial TniB protein 0.00046 414-437 / 39-62
PF00004.28 ATPase family associated with various cellular activities (AAA) 0.00047 416-436 / 1-21
PF03969.15 AFG1-like ATPase 0.00089 413-437 / 67-91
PF07728.13 AAA domain (dynein-related subfamily) 0.00092 415-437 / 1-23
PF07724.13 AAA domain (Cdc48 subfamily) 0.0011 415-437 / 5-27
PF12780.6 P-loop containing dynein motor region D4 0.0012 414-435 / 32-53
PF14532.5 Sigma-54 interaction domain 0.0014 415-480 / 23-79
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.002 414-438 / 5-29
PF05707.11 Zonular occludens toxin (Zot) 0.0025 416-433 / 3-20
PF03215.14 Rad17 cell cycle checkpoint protein 0.0057 377-437 / 18-69

Annotations of the NCBI proteins of this PHROG


5:hypothetical protein 4:DNA primase 1:virulence associated E family protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0003896 DNA primase activity
GO:0008270 zinc ion binding
GO:0004673 protein histidine kinase activity
GO:0000155 phosphorelay sensor kinase activity
GO:0004386 helicase activity
GO:0009378 four-way junction helicase activity
GO:0006260 DNA replication
GO:0003724 RNA helicase activity
GO:0016020 membrane
GO:0005524 ATP binding
GO:0000160 phosphorelay signal transduction system
GO:0008134 transcription factor binding
GO:0006270 DNA replication initiation
GO:0016887 ATPase activity
GO:0004003 ATP-dependent DNA helicase activity
GO:0006281 DNA repair
GO:0006355 regulation of transcription, DNA-templated
GO:0003723 RNA binding

Loading in process