phrog_10696 is made of 10 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
162.6 163 163


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_023724_p61 YP_009016425.1 gp62 NC_023724 Mycobacterium virus Larva Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus.
NC_028947_p58 YP_009212805.1 hypothetical protein NC_028947 Mycobacterium phage Kratio Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF185720_p61 ASR85849.1 HNH endonuclease MF185720 Mycobacterium phage Guillsminger Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_024366_p61 YP_009043663.1 endonuclease NC_024366 Mycobacterium phage OkiRoe Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
KX585251_p62 AOQ28921.1 hypothetical protein KX585251 Mycobacterium phage Waterfoul Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_031035_p60 YP_009282306.1 HNH endonuclease NC_031035 Mycobacterium phage Gengar Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_028832_p64 YP_009201697.1 hypothetical protein NC_028832 Mycobacterium phage Omnicron Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MH051255_p60 AVR77077.1 hypothetical protein MH051255 Mycobacterium phage Leston Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF185717_p62 ASM62569.1 HNH endonuclease MF185717 Mycobacterium phage AlleyCat Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF185719_p60 ASR85757.1 HNH endonuclease MF185719 Mycobacterium phage Edugator Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_22 1927 thioredoxin domain DNA, RNA and nucleotide metabolism 10 6.95E-25 15.28
phrog_1571 95 HNH endonuclease DNA, RNA and nucleotide metabolism 10 1.67E-39 29.9

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1804 Rz-like spanin lysis 90.9 0.044 95-128 / 3-35
phrog_22048 HNH endonuclease DNA, RNA and nucleotide metabolism 97.9 1.6E-08 38-95 / 3-59
phrog_3641 no annotation unknown function 99.5 5.8E-18 94-163 / 9-72
phrog_7030 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 6.6E-05 22-88 / 11-79
phrog_8372 no annotation unknown function 95.6 0.00047 94-159 / 3-57
phrog_960 HNH endonuclease DNA, RNA and nucleotide metabolism 99.9 3.1E-30 1-95 / 1-98

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05766.11 Bacteriophage Lambda NinG protein 7.7E-08 24-87 / 75-139
PF05315.10 ICEA Protein 2.7E-07 22-84 / 80-150
PF13395.5 HNH endonuclease 3.4E-07 38-84 / 1-51
PF01844.22 HNH endonuclease 4.4E-07 38-83 / 1-47
PF06147.10 Protein of unknown function (DUF968) 1.7E-06 33-88 / 125-178
PF14279.5 HNH endonuclease 2.6E-06 38-85 / 1-46
PF13391.5 HNH endonuclease 3.6E-06 38-85 / 1-46
PF16784.4 Putative HNHc nuclease 0.00055 33-84 / 121-171
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.0008 35-84 / 253-296

Annotations of the NCBI proteins of this PHROG


5:HNH endonuclease 4:hypothetical protein 1:endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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