phrog_10729 is made of 10 protein sequences and is annotated as "DNA polymerase/primase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
720 729 723


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_024366_p63 YP_009043665.1 primase/polymerase NC_024366 Mycobacterium phage OkiRoe Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
KX585251_p64 AOQ28923.1 hypothetical protein KX585251 Mycobacterium phage Waterfoul Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF185720_p63 ASR85851.1 DNA primase/polymerase MF185720 Mycobacterium phage Guillsminger Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF185719_p62 ASR85759.1 DNA primase/polymerase MF185719 Mycobacterium phage Edugator Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_028832_p66 YP_009201699.1 DNA primase NC_028832 Mycobacterium phage Omnicron Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF185717_p64 ASM62571.1 DNA primase/polymerase MF185717 Mycobacterium phage AlleyCat Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_023724_p63 YP_009016427.1 gp64 NC_023724 Mycobacterium virus Larva Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus.
NC_031035_p62 YP_009282308.1 DnaB-like replicative helicase NC_031035 Mycobacterium phage Gengar Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_028947_p60 YP_009212807.1 hypothetical protein NC_028947 Mycobacterium phage Kratio Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MH051255_p62 AVR77079.1 DNA primase/polymerase MH051255 Mycobacterium phage Leston Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1571 95 HNH endonuclease DNA, RNA and nucleotide metabolism 10 1.67E-39 29.9
phrog_16 2054 DNA helicase DNA, RNA and nucleotide metabolism 10 1.40E-24 14.97

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10342 DNA binding protein DNA, RNA and nucleotide metabolism 98.8 3.6E-12 650-713 / 6-69
phrog_1156 DNA primase DNA, RNA and nucleotide metabolism 99.3 5.3E-16 14-183 / 6-183
phrog_19 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 96.7 1.7E-05 395-596 / 193-405
phrog_2071 ATPase other 94.2 0.0043 400-421 / 4-25
phrog_239 DNA primase/helicase DNA, RNA and nucleotide metabolism 98.2 2.4E-09 394-590 / 303-527
phrog_243 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 94.9 0.0018 394-550 / 30-196
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 92.4 0.02 396-447 / 35-84
phrog_296 DNA transposition protein integration and excision 91.4 0.036 397-462 / 89-142
phrog_3022 DNA primase DNA, RNA and nucleotide metabolism 92.0 0.025 31-259 / 28-235
phrog_3123 no annotation unknown function 95.6 0.00048 394-605 / 311-543
phrog_5177 DNA polymerase/primase DNA, RNA and nucleotide metabolism 96.8 8.8E-06 14-162 / 20-170
phrog_5852 DNA polymerase/primase DNA, RNA and nucleotide metabolism 97.7 5.6E-08 16-163 / 68-229
phrog_695 DNA polymerase/primase DNA, RNA and nucleotide metabolism 98.1 2.5E-09 13-288 / 2-260
phrog_906 DNA polymerase/primase DNA, RNA and nucleotide metabolism 98.0 6.7E-09 389-563 / 560-731
phrog_97 UvsX-like recombinase other 93.7 0.0077 380-466 / 31-113

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF09250.10 Bifunctional DNA primase/polymerase, N-terminal 2.1E-16 18-163 / 1-161
PF03796.14 DnaB-like helicase C terminal domain 1E-11 398-597 / 14-239
PF00154.20 recA bacterial DNA recombination protein 1.5E-11 398-598 / 47-247
PF06745.12 KaiC 9E-11 398-596 / 14-208
PF09807.8 Elongation complex protein 6 1.3E-09 399-595 / 14-241
PF08423.10 Rad51 1.7E-09 386-578 / 22-223
PF13481.5 AAA domain 2.9E-08 397-552 / 23-186
PF07088.10 GvpD gas vesicle protein 0.00061 398-429 / 253-287
PF05625.10 PAXNEB protein 1.7E-07 498-579 / 196-275
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 1.8E-05 406-451 / 1-34
PF13479.5 AAA domain 6.9E-05 403-423 / 2-22
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 9.1E-05 405-450 / 2-38
PF05707.11 Zonular occludens toxin (Zot) 0.00012 405-424 / 2-21
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 0.00013 400-427 / 11-38
PF05621.10 Bacterial TniB protein 0.00047 404-427 / 39-62
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.00084 403-428 / 4-29
PF01637.17 ATPase domain predominantly from Archaea 0.0018 403-428 / 20-45
PF07652.13 Flavivirus DEAD domain 0.0038 402-425 / 3-27
PF07693.13 KAP family P-loop domain 0.004 401-429 / 29-57
PF02456.14 Adenovirus IVa2 protein 0.0044 405-423 / 82-100
PF00488.20 MutS domain V 0.0085 407-427 / 2-22

Annotations of the NCBI proteins of this PHROG


5:DNA primase/polymerase 2:hypothetical protein 1:primase/polymerase 1:DnaB-like replicative helicase 1:DNA primase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004673 protein histidine kinase activity
GO:0019073 viral DNA genome packaging
GO:0043752 adenosylcobinamide kinase activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0008026 ATP-dependent helicase activity
GO:0003678 DNA helicase activity
GO:0006260 DNA replication
GO:0000155 phosphorelay sensor kinase activity
GO:0009236 cobalamin biosynthetic process
GO:0005524 ATP binding
GO:0000160 phosphorelay signal transduction system
GO:0030983 mismatched DNA binding
GO:0033588 Elongator holoenzyme complex
GO:0051188 cofactor biosynthetic process
GO:0002098 tRNA wobble uridine modification
GO:0016020 membrane
GO:0003697 single-stranded DNA binding
GO:0000166 nucleotide binding
GO:0006298 mismatch repair
GO:0006281 DNA repair

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