phrog_10822 is made of 9 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
167 342 158


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF919520_p20 ATN90653.1 HNH endonuclease MF919520 Gordonia phage Lozinak Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Smoothievirus; unclassified Smoothievirus.
NC_030696_p20 YP_009269141.1 HNH endonuclease NC_030696 Gordonia phage Smoothie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Smoothievirus.
NC_023573_p54 YP_009006725.1 HNH endonuclease NC_023573 Staphylococcus phage phiSA12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Twortvirinae; Kayvirus.
p33300 no NCBI prot ID no annotation VI_04060 unknown_gi_547846574 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
MF893340_p168 ATN92931.1 hypothetical protein MF893340 Pseudomonas phage PPSC2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Otagovirus; unclassified Otagovirus.
NC_028247_p88 YP_009177335.1 HNH endonuclease NC_028247 Citrobacter phage Michonne Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Mooglevirus; unclassified Mooglevirus.
MF403008_p90 ASV44700.1 hypothetical protein MF403008 Agrobacterium phage Atu_ph07 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Polybotosvirus; Agrobacterium virus Atuph07.
MF403008_p460 AUZ95219.1 hypothetical protein MF403008 Agrobacterium phage Atu_ph07 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Polybotosvirus; Agrobacterium virus Atuph07.
NC_015569_p201 YP_004508634.1 hypothetical protein NC_015569 Synechococcus phage S-CRM01 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_8206 14 no annotation unknown function 2 4.94E-13 3.43
phrog_11962 8 no annotation unknown function 2 7.60E-14 4.24

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 94.3 0.0037 98-143 / 100-147
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 6.8E-05 89-150 / 21-83
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 98.1 5.3E-09 90-151 / 135-202
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 5.6E-06 91-149 / 54-113
phrog_14736 HNH endonuclease DNA, RNA and nucleotide metabolism 99.8 5E-24 78-156 / 11-88
phrog_14913 HNH endonuclease DNA, RNA and nucleotide metabolism 95.3 0.0008 117-151 / 58-114
phrog_15103 no annotation unknown function 95.0 0.0014 98-147 / 199-252
phrog_1571 HNH endonuclease DNA, RNA and nucleotide metabolism 94.3 0.004 109-144 / 41-84
phrog_16986 no annotation unknown function 93.3 0.01 96-147 / 17-66
phrog_1985 HNH endonuclease DNA, RNA and nucleotide metabolism 95.4 0.00069 97-145 / 65-124
phrog_19902 HNH endonuclease DNA, RNA and nucleotide metabolism 91.3 0.037 120-150 / 108-143
phrog_2255 HNH endonuclease DNA, RNA and nucleotide metabolism 97.6 1.2E-07 97-145 / 63-123
phrog_2323 HNH endonuclease DNA, RNA and nucleotide metabolism 94.2 0.0042 98-147 / 23-87
phrog_24252 HNH endonuclease DNA, RNA and nucleotide metabolism 95.0 0.0015 100-146 / 16-69
phrog_25862 HNH endonuclease DNA, RNA and nucleotide metabolism 91.7 0.03 120-145 / 109-134
phrog_2914 endonuclease VII DNA, RNA and nucleotide metabolism 90.3 0.056 99-143 / 38-75
phrog_30377 HNH endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0022 117-138 / 25-46
phrog_3106 HNH endonuclease DNA, RNA and nucleotide metabolism 97.4 5.6E-07 99-145 / 44-102
phrog_323 transcriptional regulator, D5-like transcription regulation 90.5 0.052 4-52 / 2-43
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00012 90-148 / 19-72
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0021 97-149 / 26-83
phrog_34672 no annotation unknown function 96.4 4.8E-05 14-63 / 8-57
phrog_4160 no annotation unknown function 94.7 0.0024 87-148 / 48-116
phrog_4234 HNH endonuclease DNA, RNA and nucleotide metabolism 92.8 0.015 101-144 / 29-78
phrog_4578 HNH endonuclease DNA, RNA and nucleotide metabolism 97.0 3.8E-06 114-138 / 6-30
phrog_5200 HNH endonuclease DNA, RNA and nucleotide metabolism 91.7 0.031 97-144 / 38-82
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.1E-06 82-146 / 33-96
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 95.9 0.00025 98-150 / 5-58
phrog_59 HNH endonuclease DNA, RNA and nucleotide metabolism 95.4 0.00068 111-138 / 64-91
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 95.3 0.0008 97-145 / 3-50
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 91.9 0.027 16-145 / 15-130
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 93.9 0.0062 98-145 / 67-108
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.2E-05 97-148 / 25-78
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 4.3E-05 11-151 / 53-189
phrog_9443 HNH endonuclease DNA, RNA and nucleotide metabolism 92.2 0.023 98-143 / 97-139
phrog_959 HNH endonuclease DNA, RNA and nucleotide metabolism 95.0 0.0016 119-139 / 73-93
phrog_99 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 8.5E-06 119-139 / 69-89

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04936.11 Protein of unknown function (DUF658) 1.3E-05 301-326 / 87-112
PF01710.15 Transposase 1.7E-05 194-326 / 2-94
PF06413.10 Neugrin 2.6E-05 189-241 / 5-58
PF08822.10 Protein of unknown function (DUF1804) 2.5E-05 194-326 / 2-104
PF00292.17 'Paired box' domain 3.8E-05 192-235 / 15-57
PF05766.11 Bacteriophage Lambda NinG protein 6.2E-05 117-179 / 74-136
PF12824.6 Mitochondrial ribosomal protein subunit L20 6.9E-05 190-235 / 84-131
PF07750.10 GcrA cell cycle regulator 0.0051 293-326 / 10-43
PF05315.10 ICEA Protein 0.00017 117-180 / 81-151
PF13395.5 HNH endonuclease 0.00025 132-179 / 1-51
PF04552.12 Sigma-54, DNA binding domain 0.00047 192-235 / 28-72
PF01844.22 HNH endonuclease 0.00054 132-177 / 1-46
PF09862.8 Protein of unknown function (DUF2089) 0.0011 165-234 / 11-72
PF10654.8 Protein of unknown function (DUF2481) 0.0069 287-325 / 66-103
PF12759.6 InsA C-terminal domain 0.0013 194-233 / 5-43
PF14279.5 HNH endonuclease 0.0031 132-180 / 1-46
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.0037 202-238 / 5-40
PF02796.14 Helix-turn-helix domain of resolvase 0.0047 195-233 / 6-43
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.0063 129-180 / 253-297
PF04218.12 CENP-B N-terminal DNA-binding domain 0.0061 194-233 / 6-45
PF13936.5 Helix-turn-helix domain 0.006 194-233 / 4-42
PF09607.9 Brinker DNA-binding domain 0.0065 194-234 / 5-48

Annotations of the NCBI proteins of this PHROG


4:HNH endonuclease 4:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding
GO:0006355 regulation of transcription, DNA-templated
GO:0019069 viral capsid assembly
GO:0005524 ATP binding
GO:0000150 recombinase activity
GO:0006310 DNA recombination
GO:0003677 DNA binding

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