phrog_11046 is made of 9 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
100.56 168 93


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY780159_p16 ARM37798.1 putative DNA-binding protein KY780159 Sulfolobus polyhedral virus 1 Viruses; Portogloboviridae; Alphaportoglobovirus; Sulfolobus alphaportoglobovirus 1.
NC_001338_p7 NP_039783.1 ORF F-93 NC_001338 Sulfolobus spindle-shaped virus 1 Viruses; Fuselloviridae; Alphafusellovirus.
NC_013585_p17 YP_003331422.1 putative HTH transcriptional regulator NC_013585 Acidianus spindle-shaped virus 1 (SSV1) Viruses; Fuselloviridae; Betafusellovirus.
NC_013588_p16 YP_003331499.1 hypothetical protein NC_013588 Sulfolobus spindle-shaped virus 7 (SSV7) Viruses; Fuselloviridae; Alphafusellovirus.
p91536 no NCBI prot ID no annotation VI_12481 Thermoprotei_gi_483380609_2368826_2414990 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_005361_p15 NP_963981.1 ORF E81 NC_005361 Sulfolobus virus Kamchatka 1 Viruses; Fuselloviridae; Alphafusellovirus.
p388693 no NCBI prot ID no annotation VI_04039 Thermoprotei_gi_227829020_118353_133781 Viruses; Fuselloviridae.
p91509 no NCBI prot ID no annotation VI_12481 Thermoprotei_gi_483380609_2368826_2414990 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p91535 no NCBI prot ID no annotation VI_12481 Thermoprotei_gi_483380609_2368826_2414990 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_11046 9 transcriptional regulator transcription regulation 2 3.87E-14 4.53

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11195 no annotation unknown function 92.5 0.019 5-74 / 19-90
phrog_11961 no annotation unknown function 90.5 0.054 13-75 / 45-109
phrog_12817 transcriptional regulator transcription regulation 95.8 0.0003 8-84 / 64-139
phrog_13084 no annotation unknown function 93.9 0.006 13-58 / 31-82
phrog_151 transposase integration and excision 94.5 0.0032 3-51 / 3-52
phrog_23720 no annotation unknown function 90.1 0.063 14-76 / 16-85
phrog_2538 terminase small subunit head and packaging 90.1 0.062 7-56 / 4-54
phrog_25401 DNA binding protein DNA, RNA and nucleotide metabolism 91.5 0.033 26-78 / 35-86
phrog_4221 replication initiation protein DNA, RNA and nucleotide metabolism 90.9 0.044 25-68 / 48-95
phrog_9665 transcriptional regulator transcription regulation 95.3 0.00082 14-82 / 38-114

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF11313.7 Protein of unknown function (DUF3116) 2.2E-08 31-87 / 19-82
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 2.9E-08 16-85 / 6-91
PF04079.15 Segregation and condensation complex subunit ScpB 4.7E-08 14-85 / 79-150
PF14557.5 Putative AphA-like transcriptional regulator 9E-08 16-89 / 6-92
PF14277.5 Domain of unknown function (DUF4364) 9.3E-08 22-88 / 4-74
PF07381.10 Winged helix DNA-binding domain (DUF1495) 1.2E-07 16-83 / 7-87
PF01090.18 Ribosomal protein S19e 1.3E-07 22-88 / 55-136
PF05584.10 Sulfolobus plasmid regulatory protein 2.2E-07 23-82 / 10-70
PF02334.15 Replication terminator protein 2.5E-07 30-92 / 29-108
PF03965.15 Penicillinase repressor 2.8E-07 19-82 / 4-72
PF03551.13 Transcriptional regulator PadR-like family 3.1E-07 31-84 / 13-72
PF13601.5 Winged helix DNA-binding domain 4.3E-07 23-86 / 5-71
PF09639.9 YjcQ protein 4.5E-07 31-87 / 15-83
PF04492.12 Bacteriophage replication protein O 5.7E-07 14-77 / 23-93
PF14947.5 Winged helix-turn-helix 6.8E-07 22-87 / 6-71
PF01638.16 HxlR-like helix-turn-helix 6.9E-07 22-93 / 9-83
PF09114.9 Transcription factor MotA, activation domain 8.7E-07 14-90 / 12-84
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 1.1E-06 16-87 / 3-80
PF02002.16 TFIIE alpha subunit 1.2E-06 19-88 / 13-85
PF13463.5 Winged helix DNA-binding domain 2.1E-06 21-80 / 6-67
PF10711.8 Hypothetical protein (DUF2513) 2.2E-06 23-88 / 10-86
PF09202.10 Rio2, N-terminal 2.3E-06 19-85 / 7-75
PF05732.10 Firmicute plasmid replication protein (RepL) 2.4E-06 18-67 / 55-109
PF12793.6 Sugar transport-related sRNA regulator N-term 3.1E-06 23-87 / 7-75
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 3.2E-06 18-84 / 8-73
PF09904.8 Winged helix-turn helix 4.8E-06 22-81 / 11-74
PF02319.19 E2F/DP family winged-helix DNA-binding domain 5.2E-06 22-67 / 11-57
PF01978.18 Sugar-specific transcriptional regulator TrmB 6.8E-06 17-68 / 7-57
PF02295.16 Adenosine deaminase z-alpha domain 7.3E-06 22-67 / 8-53
PF07848.11 PaaX-like protein 1E-05 31-80 / 19-70
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 1.1E-05 16-66 / 11-60
PF01475.18 Ferric uptake regulator family 1.1E-05 15-78 / 4-73
PF06969.15 HemN C-terminal domain 1.2E-05 24-81 / 12-65
PF08461.9 Ribonuclease R winged-helix domain 1.3E-05 27-82 / 7-63
PF16221.4 winged helix-turn-helix 1.5E-05 19-65 / 32-78
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 1.7E-05 31-85 / 23-75
PF14394.5 Domain of unknown function (DUF4423) 1.8E-05 20-88 / 23-93
PF09012.9 FeoC like transcriptional regulator 2E-05 27-69 / 9-50
PF06163.10 Bacterial protein of unknown function (DUF977) 2E-05 18-68 / 12-61
PF03428.12 Replication protein C N-terminal domain 2.1E-05 14-69 / 39-107
PF16864.4 Dimerisation domain 2.3E-05 21-84 / 21-79
PF08784.10 Replication protein A C terminal 2.4E-05 17-67 / 39-95
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 2.6E-05 22-76 / 5-61
PF05158.11 RNA polymerase Rpc34 subunit 4.5E-05 15-68 / 89-143
PF08222.10 CodY helix-turn-helix domain 4.7E-05 31-67 / 3-38
PF10771.8 Winged helix-turn-helix domain (DUF2582) 5E-05 16-69 / 6-58
PF01316.20 Arginine repressor, DNA binding domain 6.6E-05 21-78 / 8-66
PF01726.15 LexA DNA binding domain 7E-05 32-67 / 25-60
PF14338.5 Mrr N-terminal domain 8.4E-05 45-84 / 49-85
PF02082.19 Transcriptional regulator 8.4E-05 33-80 / 25-70
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00013 34-80 / 13-57
PF12802.6 MarR family 0.00016 23-67 / 10-55
PF04182.11 B-block binding subunit of TFIIIC 0.00016 22-68 / 6-53
PF01047.21 MarR family 0.00016 22-67 / 7-51
PF09824.8 ArsR transcriptional regulator 0.00017 18-66 / 17-61
PF04703.11 FaeA-like protein 0.00026 24-67 / 6-48
PF13412.5 Winged helix-turn-helix DNA-binding 0.00027 24-63 / 9-47
PF01022.19 Bacterial regulatory protein, arsR family 0.00027 23-63 / 7-46
PF09339.9 IclR helix-turn-helix domain 0.00028 33-66 / 19-51
PF09821.8 C-terminal AAA-associated domain 0.00036 37-85 / 2-45
PF08535.9 KorB domain 0.00042 32-82 / 3-57
PF08220.11 DeoR-like helix-turn-helix domain 0.00047 25-66 / 7-47
PF11972.7 HTH DNA binding domain 0.00051 25-64 / 6-41
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.00065 31-66 / 16-50
PF12840.6 Helix-turn-helix domain 0.00066 19-67 / 9-54
PF03297.14 S25 ribosomal protein 0.00081 24-66 / 48-89
PF14502.5 Helix-turn-helix domain 0.0013 32-67 / 6-40
PF08820.9 Domain of unknown function (DUF1803) 0.0015 21-77 / 15-65
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0016 31-66 / 20-54
PF13730.5 Helix-turn-helix domain 0.0016 43-63 / 33-52
PF07900.10 Protein of unknown function (DUF1670) 0.0016 30-67 / 93-129
PF15977.4 Winged helix-turn-helix DNA binding 0.0017 32-67 / 23-57
PF13814.5 Replication-relaxation 0.0017 27-84 / 4-59
PF00392.20 Bacterial regulatory proteins, gntR family 0.0019 30-67 / 21-58
PF01418.16 Helix-turn-helix domain, rpiR family 0.0021 16-66 / 14-67
PF05331.10 Protein of unknown function (DUF742) 0.0025 18-67 / 41-87
PF13545.5 Crp-like helix-turn-helix domain 0.0025 31-66 / 26-60
PF07037.10 Putative transcription regulator (DUF1323) 0.0025 34-87 / 2-55
PF09756.8 DDRGK domain 0.0029 24-82 / 107-164
PF09397.9 Ftsk gamma domain 0.0043 24-67 / 11-53
PF05043.12 Mga helix-turn-helix domain 0.0058 20-60 / 18-57
PF13404.5 AsnC-type helix-turn-helix domain 0.0061 26-57 / 11-41
PF07183.10 Protein of unknown function (DUF1403) 0.0066 19-67 / 275-320
PF00325.19 Bacterial regulatory proteins, crp family 0.0076 34-63 / 4-32
PF08279.11 HTH domain 0.0082 31-61 / 14-43

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein 1:HTH transcriptional regulator 1:DNA-binding protein 1:protein of an unannotated phage

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0009378 four-way junction helicase activity
GO:0007131 reciprocal meiotic recombination
GO:0005622 intracellular
GO:0006383 transcription by RNA polymerase III
GO:0009289 pilus
GO:0006260 DNA replication
GO:0004674 protein serine/threonine kinase activity
GO:0006468 protein phosphorylation
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0005840 ribosome
GO:0006274 DNA replication termination
GO:0003700 DNA binding transcription factor activity
GO:0004252 serine-type endopeptidase activity
GO:0006281 DNA repair
GO:0051304 chromosome separation
GO:0006355 regulation of transcription, DNA-templated
GO:0006525 arginine metabolic process
GO:0006412 translation
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0006508 proteolysis
GO:0005666 DNA-directed RNA polymerase III complex
GO:0043565 sequence-specific DNA binding
GO:0005524 ATP binding
GO:0006276 plasmid maintenance

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