phrog_11187 is made of 9 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
62.67 65 63


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p82712 no NCBI prot ID no annotation VI_00440 Bacilli_gi_411107839 Viruses.
JX564242_p14 AFV51043.1 putative cro protein JX564242 Lactococcus phage Q33 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p264164 no NCBI prot ID no annotation VI_05336 Bacilli_gi_544798983_62258_92912 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p229064 no NCBI prot ID no annotation VI_04473 Bacilli_gi_290891529 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Lactococcus phage P335 sensu lato.
NC_004746_p27 NP_839918.1 hypothetical protein NC_004746 Lactococcus phage P335 sensu lato Viruses; Caudovirales; Siphoviridae.
p376168 no NCBI prot ID no annotation VI_05333 Bacilli_gi_544795903 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_002669_p14 NP_076764.1 repressor NC_002669 Lactococcus phage bIL310 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p24836 no NCBI prot ID no annotation VI_00788 Bacilli_gi_554764098_22736_94690 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p298849 no NCBI prot ID no annotation VI_05329 Bacilli_gi_544790728_13659_39639 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Lactococcus phage bIL310.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2198 68 Alt-like transcription activator transcription regulation 4 4.24E-18 8.49
phrog_2657 54 transcriptional regulator transcription regulation 3 1.16E-14 5.06

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11145 DNA binding protein DNA, RNA and nucleotide metabolism 90.6 0.05 21-61 / 2-42
phrog_1373 transcriptional regulator transcription regulation 94.9 0.0018 10-57 / 34-81
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 94.5 0.003 18-47 / 21-50
phrog_1468 transcriptional repressor transcription regulation 94.3 0.004 4-54 / 4-57
phrog_147 transcriptional regulator transcription regulation 95.9 0.0002 8-62 / 3-66
phrog_15481 no annotation unknown function 92.7 0.016 1-40 / 1-39
phrog_15534 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.7 0.031 17-61 / 36-86
phrog_2328 transcriptional repressor transcription regulation 91.0 0.042 8-55 / 16-63
phrog_2439 transcriptional regulator transcription regulation 91.2 0.039 10-43 / 9-42
phrog_2538 terminase small subunit head and packaging 90.6 0.05 3-44 / 3-43
phrog_2907 excisionase integration and excision 90.2 0.059 18-43 / 3-28
phrog_2967 transcriptional regulator transcription regulation 94.6 0.0027 5-57 / 6-59
phrog_296 DNA transposition protein integration and excision 91.7 0.03 8-61 / 2-56
phrog_309 terminase small subunit head and packaging 92.7 0.016 17-55 / 21-74
phrog_34341 transcriptional regulator transcription regulation 91.4 0.035 3-48 / 70-112
phrog_351 RNA polymerase sigma factor transcription regulation 91.9 0.028 1-43 / 173-217
phrog_3 transcriptional repressor transcription regulation 95.6 0.00051 8-44 / 4-40
phrog_4583 transcriptional repressor transcription regulation 94.4 0.0033 3-47 / 6-52
phrog_4745 DNA binding protein DNA, RNA and nucleotide metabolism 90.5 0.052 18-61 / 2-60
phrog_4779 transcriptional regulator transcription regulation 94.6 0.0028 11-44 / 5-38
phrog_6288 no annotation unknown function 92.6 0.018 11-61 / 15-70
phrog_668 HTH DNA binding protein DNA, RNA and nucleotide metabolism 92.0 0.025 15-62 / 31-85
phrog_66 excisionase and transcriptional regulator integration and excision 94.2 0.0042 17-44 / 6-33
phrog_6831 transcriptional regulator transcription regulation 95.5 0.00057 1-55 / 1-52
phrog_6962 no annotation unknown function 93.2 0.012 12-45 / 6-39
phrog_7950 transcriptional repressor transcription regulation 95.5 0.00053 4-61 / 9-68
phrog_8038 no annotation unknown function 92.3 0.021 2-43 / 1-36
phrog_8898 no annotation unknown function 90.2 0.06 15-43 / 9-37
phrog_8 transcriptional regulator transcription regulation 96.1 0.00014 8-43 / 2-36
phrog_955 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.0 0.0055 9-44 / 38-73

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 9.6E-08 7-44 / 10-47
PF01381.21 Helix-turn-helix 1.1E-07 17-62 / 6-51
PF13744.5 Helix-turn-helix domain 1.4E-07 15-62 / 26-74
PF14590.5 Domain of unknown function (DUF4447) 1.5E-07 6-45 / 6-45
PF05339.10 Protein of unknown function (DUF739) 2.8E-07 15-61 / 11-57
PF04645.11 Protein of unknown function, DUF603 6.4E-07 4-56 / 4-59
PF13413.5 Helix-turn-helix domain 8.8E-07 17-62 / 6-57
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 2.3E-06 20-62 / 11-53
PF13443.5 Cro/C1-type HTH DNA-binding domain 2.6E-06 19-62 / 9-55
PF12844.6 Helix-turn-helix domain 4.9E-06 19-60 / 11-52
PF08667.9 BetR domain 5.9E-06 12-61 / 10-63
PF13560.5 Helix-turn-helix domain 6.7E-06 16-61 / 10-56
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 9.9E-06 18-61 / 80-122
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 2.5E-05 22-60 / 10-48
PF05269.10 Bacteriophage CII protein 3.5E-05 17-57 / 20-59
PF08965.9 Domain of unknown function (DUF1870) 5.3E-05 13-45 / 7-41
PF12116.7 Stage III sporulation protein D 8.4E-05 19-59 / 18-59
PF14549.5 DNA-binding transcriptional regulator Cro 9.2E-05 18-61 / 8-47
PF00356.20 Bacterial regulatory proteins, lacI family 0.00014 24-44 / 3-23
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.00029 19-59 / 125-165
PF00157.16 Pou domain - N-terminal to homeobox domain 0.00051 11-43 / 11-49
PF13693.5 Winged helix-turn-helix DNA-binding 0.0012 19-43 / 14-38
PF10654.8 Protein of unknown function (DUF2481) 0.0053 18-44 / 78-104

Annotations of the NCBI proteins of this PHROG


1:hypothetical protein 1:repressor 1:cro protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006355 regulation of transcription, DNA-templated
GO:0005634 nucleus
GO:0045893 positive regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding

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