phrog_11420 is made of 9 protein sequences and is annotated as "DNA binding protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
88.11 123 85


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MG711461_p38 AUV56390.1 putative DNA binding domain-containing protein MG711461 Faecalibacterium phage FP_Lagaffe Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Lagaffevirus; Faecalibacterium virus Lagaffe.
p71258 no NCBI prot ID no annotation VI_01189 Clostridia_gi_283767241_16075_65536 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p78239 no NCBI prot ID no annotation VI_01154 Clostridia_gi_256402711_179985_228048 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p255870 no NCBI prot ID no annotation VI_01237 Clostridia_gi_547766152_28262_59617 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p59380 no NCBI prot ID no annotation VI_01197 Clostridia_gi_355635008_30994_83331 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p15388 no NCBI prot ID no annotation VI_01194 Clostridia_gi_373121103_353147_435681 Viruses.
p40363 no NCBI prot ID no annotation VI_04047 unknown_gi_547191751 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae; Vibrio phage X29.
p87599 no NCBI prot ID no annotation VI_01285 Clostridia_gi_551720650_456133_502893 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p386324 no NCBI prot ID no annotation VI_04802 Bacilli_gi_418964126 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_17847 5 no annotation unknown function 4 9.39E-26 16.15

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11138 no annotation unknown function 92.7 0.017 7-50 / 89-132
phrog_11302 no annotation unknown function 96.5 3.9E-05 5-80 / 1-68
phrog_125 DNA invertase DNA, RNA and nucleotide metabolism 93.8 0.0065 15-48 / 148-181
phrog_12823 no annotation unknown function 94.7 0.0022 3-46 / 6-49
phrog_1303 DNA binding protein DNA, RNA and nucleotide metabolism 93.1 0.012 8-50 / 28-70
phrog_1373 transcriptional regulator transcription regulation 90.5 0.053 20-47 / 39-66
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 91.2 0.039 23-75 / 21-62
phrog_151 transposase integration and excision 95.3 0.00084 6-52 / 3-50
phrog_1558 no annotation unknown function 92.0 0.025 16-49 / 108-141
phrog_1740 RNA polymerase sigma factor transcription regulation 94.7 0.0023 8-49 / 125-166
phrog_20133 no annotation unknown function 95.2 0.0011 5-73 / 1-70
phrog_20467 HNH endonuclease DNA, RNA and nucleotide metabolism 95.8 0.00028 9-50 / 54-95
phrog_20487 no annotation unknown function 96.3 7.7E-05 5-72 / 1-61
phrog_2538 terminase small subunit head and packaging 91.2 0.039 14-47 / 8-41
phrog_309 terminase small subunit head and packaging 93.5 0.0087 14-44 / 13-43
phrog_323 endonuclease DNA, RNA and nucleotide metabolism 91.2 0.038 7-48 / 47-87
phrog_3288 transcriptional regulator transcription regulation 92.4 0.021 10-71 / 354-417
phrog_3512 sigma factor transcription regulation 94.5 0.003 10-50 / 67-107
phrog_351 RNA polymerase sigma factor transcription regulation 91.9 0.027 7-48 / 173-217
phrog_3910 transcriptional regulator transcription regulation 92.0 0.026 20-47 / 74-101
phrog_3 transcriptional repressor transcription regulation 91.3 0.037 23-50 / 14-40
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 90.2 0.06 15-49 / 10-44
phrog_4494 no annotation unknown function 93.8 0.0068 11-50 / 3-42
phrog_4646 transposase integration and excision 99.5 1.1E-18 5-81 / 2-80
phrog_517 HTH DNA binding protein DNA, RNA and nucleotide metabolism 97.0 3.8E-06 8-47 / 62-101
phrog_5536 no annotation unknown function 95.0 0.0015 7-50 / 3-46
phrog_6223 transcriptional repressor transcription regulation 90.1 0.063 22-74 / 14-59
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 92.0 0.026 10-52 / 4-46
phrog_66 excisionase and transcriptional regulator integration and excision 94.1 0.005 27-50 / 11-34
phrog_6831 transcriptional regulator transcription regulation 92.8 0.015 15-67 / 5-51
phrog_7344 terminase small subunit head and packaging 90.0 0.064 9-44 / 10-45
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 90.0 0.064 13-51 / 5-44
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 95.2 0.0011 11-48 / 5-41

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00292.17 'Paired box' domain 0.00032 3-68 / 38-125
PF01710.15 Transposase 0.00058 3-71 / 23-95
PF07141.10 Putative bacteriophage terminase small subunit 1.3E-07 33-72 / 18-57
PF07750.10 GcrA cell cycle regulator 1.5E-07 31-72 / 3-45
PF09607.9 Brinker DNA-binding domain 1.9E-07 29-72 / 4-51
PF14493.5 Helix-turn-helix domain 2E-07 39-73 / 5-39
PF12759.6 InsA C-terminal domain 2.8E-07 30-70 / 5-45
PF08822.10 Protein of unknown function (DUF1804) 0.00064 3-72 / 24-106
PF04936.11 Protein of unknown function (DUF658) 6.1E-06 46-72 / 14-40
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 1.1E-06 37-72 / 4-39
PF13011.5 leucine-zipper of insertion element IS481 1.2E-06 29-73 / 6-51
PF13542.5 Helix-turn-helix domain of transposase family ISL3 3E-06 30-70 / 11-50
PF10668.8 Phage terminase small subunit 3E-06 30-72 / 4-48
PF02796.14 Helix-turn-helix domain of resolvase 3.5E-06 34-69 / 9-44
PF05344.10 Domain of Unknown Function (DUF746) 3.7E-06 43-73 / 9-39
PF16677.4 DNA-packaging protein gp3 4.8E-06 30-70 / 5-53
PF10654.8 Protein of unknown function (DUF2481) 5.7E-06 31-70 / 65-104
PF04218.12 CENP-B N-terminal DNA-binding domain 6.5E-06 30-71 / 6-48
PF13411.5 MerR HTH family regulatory protein 6.7E-06 48-73 / 2-27
PF13936.5 Helix-turn-helix domain 6.9E-06 32-69 / 6-43
PF06627.10 Protein of unknown function (DUF1153) 7.1E-06 28-73 / 27-73
PF04552.12 Sigma-54, DNA binding domain 7.5E-06 29-71 / 29-73
PF13309.5 HTH domain 9.2E-06 30-68 / 19-63
PF03333.12 Adhesin biosynthesis transcription regulatory protein 1.1E-05 31-71 / 40-80
PF01527.19 Transposase 1.4E-05 31-71 / 5-46
PF06322.10 Phage NinH protein 1.6E-05 45-72 / 15-42
PF12824.6 Mitochondrial ribosomal protein subunit L20 1.6E-05 28-70 / 86-131
PF11427.7 Tc3 transposase 1.7E-05 32-71 / 6-45
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 1.7E-05 44-71 / 17-44
PF16087.4 Domain of unknown function (DUF4817) 1.8E-05 34-72 / 3-50
PF15978.4 Tn7-like transposition protein D 2.3E-05 31-72 / 187-229
PF13518.5 Helix-turn-helix domain 2.8E-05 38-73 / 4-38
PF08765.10 Mor transcription activator family 2.8E-05 39-72 / 66-98
PF05331.10 Protein of unknown function (DUF742) 3.4E-05 29-72 / 37-79
PF07638.10 ECF sigma factor 3.9E-05 31-71 / 134-174
PF13384.5 Homeodomain-like domain 4.9E-05 37-70 / 8-41
PF17443.1 Uncharacterized protein pXO2-72 7.8E-05 45-70 / 7-32
PF02954.18 Bacterial regulatory protein, Fis family 8.5E-05 45-69 / 15-39
PF01371.18 Trp repressor protein 8.5E-05 39-71 / 41-73
PF05225.15 helix-turn-helix, Psq domain 8.9E-05 44-71 / 14-42
PF13551.5 Winged helix-turn helix 0.0001 42-73 / 7-38
PF13412.5 Winged helix-turn-helix DNA-binding 0.00012 45-72 / 16-43
PF13022.5 Helix-turn-helix of insertion element transposase 0.00013 46-69 / 25-48
PF16509.4 TrfB plasmid transcriptional repressor 0.00015 33-71 / 18-56
PF08281.11 Sigma-70, region 4 0.00015 43-70 / 23-50
PF01381.21 Helix-turn-helix 0.00015 44-69 / 7-32
PF11112.7 Pyocin activator protein PrtN 0.00018 46-71 / 13-39
PF07453.12 NUMOD1 domain 0.0002 47-67 / 20-40
PF00356.20 Bacterial regulatory proteins, lacI family 0.00021 48-70 / 1-23
PF06806.11 Putative excisionase (DUF1233) 0.00021 47-68 / 10-31
PF04545.15 Sigma-70, region 4 0.00022 44-70 / 22-48
PF13556.5 PucR C-terminal helix-turn-helix domain 0.00022 44-72 / 10-38
PF08535.9 KorB domain 0.00022 45-72 / 2-29
PF00376.22 MerR family regulatory protein 0.00023 49-70 / 2-23
PF11242.7 Protein of unknown function (DUF2774) 0.00023 39-71 / 7-39
PF09862.8 Protein of unknown function (DUF2089) 0.00024 30-72 / 33-75
PF13404.5 AsnC-type helix-turn-helix domain 0.00028 45-70 / 16-41
PF10975.7 Protein of unknown function (DUF2802) 0.00031 32-67 / 29-64
PF13591.5 MerR HTH family regulatory protein 0.00034 47-71 / 1-25
PF08004.10 Protein of unknown function (DUF1699) 0.00034 32-67 / 90-129
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.00036 47-68 / 4-25
PF06413.10 Neugrin 0.00036 28-69 / 8-52
PF07278.10 Protein of unknown function (DUF1441) 0.00037 47-71 / 2-26
PF07825.10 Excisionase-like protein 0.00041 47-72 / 3-30
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 0.00048 31-71 / 18-58
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00054 45-72 / 10-37
PF13413.5 Helix-turn-helix domain 0.00056 44-69 / 7-32
PF10743.8 Regulatory phage protein cox 0.00056 45-71 / 10-36
PF09035.9 Excisionase from transposon Tn916 0.0006 45-69 / 14-38
PF12116.7 Stage III sporulation protein D 0.00063 45-70 / 18-43
PF02042.14 RWP-RK domain 0.00065 45-71 / 11-37
PF02001.15 Protein of unknown function DUF134 0.00065 31-71 / 32-72
PF07374.10 Protein of unknown function (DUF1492) 0.00074 33-70 / 58-95
PF07037.10 Putative transcription regulator (DUF1323) 0.00076 47-69 / 1-23
PF06530.11 Phage antitermination protein Q 0.00078 33-71 / 66-104
PF04967.11 HTH DNA binding domain 0.00084 47-71 / 24-48
PF12728.6 Helix-turn-helix domain 0.001 47-70 / 2-26
PF00196.18 Bacterial regulatory proteins, luxR family 0.001 40-71 / 11-42
PF12964.6 Protein of unknown function (DUF3853) 0.001 46-71 / 45-70
PF16264.4 SatD family (SatD) 0.0013 31-70 / 151-195
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.0013 48-69 / 53-74
PF07471.11 Phage DNA packaging protein Nu1 0.0015 47-70 / 3-26
PF00325.19 Bacterial regulatory proteins, crp family 0.0016 47-71 / 3-27
PF12802.6 MarR family 0.0018 47-72 / 22-47
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0019 45-72 / 22-49
PF07506.10 RepB plasmid partitioning protein 0.0019 39-70 / 14-45
PF00440.22 Bacterial regulatory proteins, tetR family 0.002 47-70 / 16-39
PF07618.10 Protein of unknown function (DUF1580) 0.0023 51-70 / 7-26
PF06971.12 Putative DNA-binding protein N-terminus 0.0033 46-67 / 27-48
PF01022.19 Bacterial regulatory protein, arsR family 0.0035 46-71 / 16-41
PF08222.10 CodY helix-turn-helix domain 0.0036 46-72 / 4-30
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.0042 45-69 / 9-34
PF01418.16 Helix-turn-helix domain, rpiR family 0.0048 46-71 / 34-59
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 0.005 44-70 / 21-47
PF12793.6 Sugar transport-related sRNA regulator N-term 0.0058 45-73 / 17-45
PF09182.9 Bacterial purine repressor, N-terminal 0.0059 45-72 / 19-46
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 0.0059 37-72 / 11-48
PF08279.11 HTH domain 0.0064 45-72 / 14-41
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.0067 47-67 / 9-29
PF14549.5 DNA-binding transcriptional regulator Cro 0.0067 45-66 / 9-29
PF05339.10 Protein of unknown function (DUF739) 0.0079 45-69 / 15-39
PF05043.12 Mga helix-turn-helix domain 0.0083 46-72 / 30-56
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.0085 46-69 / 11-35
PF13744.5 Helix-turn-helix domain 0.0092 45-69 / 30-54

Annotations of the NCBI proteins of this PHROG


1:DNA binding domain-containing protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005622 intracellular
GO:0016987 sigma factor activity
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0000150 recombinase activity
GO:0006313 transposition, DNA-mediated
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0006352 DNA-templated transcription, initiation
GO:0051775 response to redox state
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0019069 viral capsid assembly
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0005524 ATP binding
GO:0043565 sequence-specific DNA binding
GO:0004803 transposase activity

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