phrog_11473 is made of 9 protein sequences and is annotated as "HTH DNA binding protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
165 206 160


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
JQ698665_p77 AFL46570.1 hypothetical protein JQ698665 Mycobacterium virus Nepal Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus.
NC_023723_p75 YP_009016340.1 hypothetical protein NC_023723 Mycobacterium phage Aeneas Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus; unclassified Fromanvirus.
NC_023720_p70 YP_009016056.1 gp70 NC_023720 Mycobacterium virus Perseus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus.
NC_023862_p78 YP_009021646.1 hypothetical protein NC_023862 Mycobacterium phage Alsfro Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus; unclassified Fromanvirus.
NC_028804_p77 YP_009199037.1 hypothetical protein NC_028804 Mycobacterium phage Barriga Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus; unclassified Fromanvirus.
NC_022329_p72 YP_008531051.1 hypothetical protein NC_022329 Mycobacterium phage PhrostyMug Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus; unclassified Fromanvirus.
KF279416_p75 AGU92375.1 hypothetical protein KF279416 Mycobacterium phage SargentShorty9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus; unclassified Fromanvirus.
MF668283_p74 ASZ74041.1 helix-turn-helix DNA binding domain protein MF668283 Mycobacterium phage Smairt Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus; unclassified Fromanvirus.
p323631 no NCBI prot ID no annotation VI_00045 Actinobacteria_gi_484005549 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_12774 8 no annotation unknown function 8 0 1000
phrog_14169 7 zinc-finger domain protein other 7 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
no PHROGs similar                                                                           

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 6.9E-06 95-150 / 6-56
PF09114.9 Transcription factor MotA, activation domain 1.9E-05 93-169 / 12-82
PF11313.7 Protein of unknown function (DUF3116) 3.3E-05 116-167 / 20-81
PF02319.19 E2F/DP family winged-helix DNA-binding domain 3.5E-05 115-149 / 22-56
PF04358.12 DsrC like protein 5.4E-05 92-149 / 34-94
PF14277.5 Domain of unknown function (DUF4364) 6E-05 115-166 / 14-71
PF14557.5 Putative AphA-like transcriptional regulator 6.1E-05 92-167 / 3-89
PF04492.12 Bacteriophage replication protein O 6.8E-05 92-149 / 22-82
PF07381.10 Winged helix DNA-binding domain (DUF1495) 8.8E-05 96-148 / 8-66
PF01090.18 Ribosomal protein S19e 0.00012 115-167 / 64-134
PF16221.4 winged helix-turn-helix 0.00013 115-147 / 45-77
PF09012.9 FeoC like transcriptional regulator 0.00013 115-150 / 13-48
PF05584.10 Sulfolobus plasmid regulatory protein 0.00015 115-149 / 17-51
PF01726.15 LexA DNA binding domain 0.00016 116-149 / 25-59
PF03965.15 Penicillinase repressor 0.00018 117-160 / 19-69
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.00018 95-149 / 11-60
PF14947.5 Winged helix-turn-helix 0.00023 115-165 / 15-68
PF10711.8 Hypothetical protein (DUF2513) 0.00024 115-169 / 17-86
PF09202.10 Rio2, N-terminal 0.00027 115-163 / 23-72
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.00028 115-150 / 21-56
PF04079.15 Segregation and condensation complex subunit ScpB 0.00029 92-165 / 78-149
PF09639.9 YjcQ protein 0.00029 115-168 / 15-83
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 0.00031 115-163 / 24-71
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.00034 115-163 / 23-72
PF13601.5 Winged helix DNA-binding domain 0.00047 115-149 / 13-47
PF13463.5 Winged helix DNA-binding domain 0.00051 115-149 / 16-50
PF02002.16 TFIIE alpha subunit 0.00052 115-149 / 25-59
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 0.00053 115-148 / 15-50
PF02295.16 Adenosine deaminase z-alpha domain 0.00057 115-150 / 17-53
PF08222.10 CodY helix-turn-helix domain 0.00057 115-149 / 3-37
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 0.00058 119-168 / 29-80
PF13412.5 Winged helix-turn-helix DNA-binding 0.00063 115-146 / 16-47
PF14394.5 Domain of unknown function (DUF4423) 0.00067 115-150 / 34-72
PF01638.16 HxlR-like helix-turn-helix 0.00067 115-165 / 18-74
PF03428.12 Replication protein C N-terminal domain 0.00071 88-149 / 34-104
PF08784.10 Replication protein A C terminal 0.00074 94-149 / 37-94
PF02334.15 Replication terminator protein 0.00075 115-170 / 30-105
PF06163.10 Bacterial protein of unknown function (DUF977) 0.00075 115-150 / 25-60
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00084 115-149 / 17-51
PF03551.13 Transcriptional regulator PadR-like family 0.0009 115-149 / 13-49
PF12802.6 MarR family 0.00091 117-149 / 22-54
PF09904.8 Winged helix-turn helix 0.0012 115-148 / 20-53
PF07848.11 PaaX-like protein 0.0012 115-149 / 19-56
PF05732.10 Firmicute plasmid replication protein (RepL) 0.0013 92-150 / 49-109
PF01022.19 Bacterial regulatory protein, arsR family 0.0014 115-146 / 15-46
PF09824.8 ArsR transcriptional regulator 0.0015 115-149 / 29-61
PF02082.19 Transcriptional regulator 0.0016 117-148 / 25-56
PF01047.21 MarR family 0.0017 115-149 / 16-50
PF09339.9 IclR helix-turn-helix domain 0.0019 117-148 / 19-50
PF00392.20 Bacterial regulatory proteins, gntR family 0.0022 115-149 / 22-57
PF08461.9 Ribonuclease R winged-helix domain 0.0025 116-162 / 12-62
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0025 115-149 / 20-54
PF06969.15 HemN C-terminal domain 0.003 115-149 / 19-54
PF04182.11 B-block binding subunit of TFIIIC 0.0031 115-149 / 17-51
PF05158.11 RNA polymerase Rpc34 subunit 0.0033 93-149 / 88-141
PF13730.5 Helix-turn-helix domain 0.0033 118-146 / 28-52
PF15977.4 Winged helix-turn-helix DNA binding 0.0037 116-149 / 23-56
PF05331.10 Protein of unknown function (DUF742) 0.0041 93-149 / 37-86
PF12840.6 Helix-turn-helix domain 0.0041 115-149 / 22-53
PF09182.9 Bacterial purine repressor, N-terminal 0.0041 115-147 / 19-56
PF01475.18 Ferric uptake regulator family 0.0044 115-149 / 21-60
PF16864.4 Dimerisation domain 0.0049 115-163 / 31-77
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.0056 118-149 / 13-47
PF14502.5 Helix-turn-helix domain 0.0058 115-149 / 5-39
PF07900.10 Protein of unknown function (DUF1670) 0.0072 115-149 / 94-128
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0076 115-149 / 16-50

Annotations of the NCBI proteins of this PHROG


7:hypothetical protein 1:helix-turn-helix DNA binding domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006276 plasmid maintenance
GO:0005524 ATP binding
GO:0005666 DNA-directed RNA polymerase III complex
GO:0006508 proteolysis
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0006355 regulation of transcription, DNA-templated
GO:0051304 chromosome separation
GO:0006412 translation
GO:0006281 DNA repair
GO:0004252 serine-type endopeptidase activity
GO:0003700 DNA binding transcription factor activity
GO:0005840 ribosome
GO:0006274 DNA replication termination
GO:0006468 protein phosphorylation
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0006383 transcription by RNA polymerase III
GO:0006260 DNA replication
GO:0004674 protein serine/threonine kinase activity
GO:0007131 reciprocal meiotic recombination
GO:0009378 four-way junction helicase activity
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated

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