phrog_12023 is made of 8 protein sequences and is annotated as "DNA topoisomerase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
71 71 71


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY554774_p99 ARM67312.1 DNA gyrase KY554774 Lactococcus phage AM9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554775_p98 ARM67490.1 DNA gyrase KY554775 Lactococcus phage AM11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554777_p102 ARM67672.1 subunit B of ATP-hydrolyzing DNA topoisomerase KY554777 Lactococcus phage LW81 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554770_p98 ARM66580.1 DNA gyrase KY554770 Lactococcus phage AM3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554769_p98 ARM66403.1 DNA gyrase KY554769 Lactococcus phage AM2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554768_p99 ARM66226.1 DNA gyrase KY554768 Lactococcus phage AM1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554776_p99 ARQ95678.1 DNA gyrase KY554776 Lactococcus phage AM12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554773_p98 ARM67133.1 DNA gyrase KY554773 Lactococcus phage AM8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_551 251 DNA topoisomerase II DNA, RNA and nucleotide metabolism 8 1.01E-28 19.12
phrog_7168 16 homing endonuclease DNA, RNA and nucleotide metabolism 7 1.55E-35 25.93

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_28877 DNA topoisomerase II DNA, RNA and nucleotide metabolism 98.0 7.3E-09 3-66 / 573-635
phrog_543 DNA topoisomerase II large subunit DNA, RNA and nucleotide metabolism 97.3 8.4E-07 2-59 / 553-605

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00986.20 DNA gyrase B subunit, carboxyl terminus 3E-15 2-59 / 6-63
PF16898.4 C-terminal associated domain of TOPRIM 5.2E-14 2-65 / 37-99

Annotations of the NCBI proteins of this PHROG


7:DNA gyrase 1:subunit B of ATP-hydrolyzing DNA topoisomerase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K02470 gyrB : DNA gyrase subunit B [EC:5.99.1.3] no pathways 77 8

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006265 DNA topological change
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005524 ATP binding
GO:0003677 DNA binding

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