phrog_12156 is made of 8 protein sequences and is annotated as "DNA helicase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
472.12 564 496


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_026588_p31 YP_009124583.1 RecG-like DNA helicase NC_026588 Mycobacterium phage Squirty Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_031061_p38 YP_009286083.1 hypothetical protein NC_031061 Gordonia phage Nymphadora Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nymbaxtervirinae; Nymphadoravirus; Gordonia virus Nymphadora.
p271763 no NCBI prot ID no annotation VI_03559 Gammaproteobacteria_gi_308185541_2856622_2886414 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p781 no NCBI prot ID no annotation VI_01291 Clostridia_gi_512436336 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p53310 no NCBI prot ID no annotation VI_04075 Zetaproteobacteria_gi_483101500 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p378547 no NCBI prot ID no annotation VI_04003 Negativicutes_gi_545448349 Viruses.
NC_005964_p1 YP_009173773.1 putative ATP-dependent DNA helicase NC_005964 Mycoplasma phage phiMFV1 Viruses; unclassified viruses; unclassified bacterial viruses.
p306169 no NCBI prot ID no annotation VI_05773 Clostridia_gi_307243547 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
no colocalized PHROGS                                                                                          

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1123 no annotation unknown function 92.9 0.015 413-465 / 18-70
phrog_1368 transcriptional regulator transcription regulation 92.2 0.022 414-472 / 8-68
phrog_142 Ren-like exclusion protein moron, auxiliary metabolic gene and host takeover 92.3 0.022 416-472 / 3-60
phrog_1687 MarR family transcrition regulator transcription regulation 94.1 0.005 418-471 / 6-59
phrog_2440 transcriptional regulator transcription regulation 94.9 0.0017 415-474 / 10-68
phrog_3502 no annotation unknown function 95.9 0.00021 412-469 / 3-66
phrog_5978 no annotation unknown function 91.8 0.028 415-472 / 306-364

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04326.13 Putative DNA-binding domain 8.8E-17 27-149 / 1-119
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 2E-06 430-499 / 6-92
PF14501.5 GHKL domain 2.3E-06 299-406 / 3-101
PF11313.7 Protein of unknown function (DUF3116) 2.8E-06 436-501 / 11-83
PF09114.9 Transcription factor MotA, activation domain 4.3E-06 428-504 / 12-85
PF04079.15 Segregation and condensation complex subunit ScpB 4.7E-06 427-498 / 78-150
PF07381.10 Winged helix DNA-binding domain (DUF1495) 6.9E-06 430-497 / 7-88
PF14277.5 Domain of unknown function (DUF4364) 1.1E-05 435-501 / 3-74
PF13589.5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1.1E-05 300-410 / 3-118
PF01090.18 Ribosomal protein S19e 1.2E-05 435-503 / 54-138
PF02334.15 Replication terminator protein 1.2E-05 435-504 / 21-107
PF05584.10 Sulfolobus plasmid regulatory protein 1.2E-05 432-495 / 6-70
PF03965.15 Penicillinase repressor 1.2E-05 432-494 / 3-71
PF14557.5 Putative AphA-like transcriptional regulator 1.3E-05 429-502 / 5-92
PF13601.5 Winged helix DNA-binding domain 1.3E-05 436-504 / 4-76
PF02518.25 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1.6E-05 296-410 / 2-108
PF03551.13 Transcriptional regulator PadR-like family 1.6E-05 444-498 / 12-73
PF04492.12 Bacteriophage replication protein O 1.7E-05 429-491 / 24-94
PF14947.5 Winged helix-turn-helix 3.1E-05 435-502 / 5-73
PF13581.5 Histidine kinase-like ATPase domain 3.1E-05 294-406 / 25-125
PF13463.5 Winged helix DNA-binding domain 4.5E-05 434-493 / 5-67
PF14394.5 Domain of unknown function (DUF4423) 4.7E-05 432-497 / 21-89
PF09639.9 YjcQ protein 5.1E-05 445-501 / 15-84
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 5.1E-05 430-501 / 3-81
PF12793.6 Sugar transport-related sRNA regulator N-term 6.9E-05 436-501 / 6-76
PF02002.16 TFIIE alpha subunit 7.9E-05 433-500 / 13-84
PF01638.16 HxlR-like helix-turn-helix 9.4E-05 435-501 / 8-78
PF02295.16 Adenosine deaminase z-alpha domain 9.5E-05 434-490 / 6-62
PF09202.10 Rio2, N-terminal 9.7E-05 432-498 / 6-75
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.0001 430-489 / 6-65
PF10711.8 Hypothetical protein (DUF2513) 0.00013 435-501 / 8-86
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.00015 435-480 / 10-57
PF07848.11 PaaX-like protein 0.00017 445-493 / 19-70
PF05732.10 Firmicute plasmid replication protein (RepL) 0.00017 432-480 / 55-109
PF09904.8 Winged helix-turn helix 0.00018 435-494 / 10-74
PF09012.9 FeoC like transcriptional regulator 0.00028 438-482 / 6-50
PF01475.18 Ferric uptake regulator family 0.00031 429-491 / 4-73
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.00031 445-499 / 23-76
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 0.00032 430-498 / 6-74
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.00033 430-480 / 11-61
PF16221.4 winged helix-turn-helix 0.00037 433-478 / 32-78
PF08461.9 Ribonuclease R winged-helix domain 0.00053 438-496 / 4-64
PF06163.10 Bacterial protein of unknown function (DUF977) 0.00055 431-488 / 11-68
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 0.00059 435-491 / 4-63
PF08784.10 Replication protein A C terminal 0.00065 430-480 / 38-95
PF08222.10 CodY helix-turn-helix domain 0.00069 445-482 / 3-40
PF03428.12 Replication protein C N-terminal domain 0.0007 428-481 / 39-106
PF09824.8 ArsR transcriptional regulator 0.00071 431-492 / 16-84
PF01316.20 Arginine repressor, DNA binding domain 0.00078 434-492 / 7-67
PF16864.4 Dimerisation domain 0.0011 434-498 / 20-80
PF04182.11 B-block binding subunit of TFIIIC 0.0013 435-481 / 5-53
PF06969.15 HemN C-terminal domain 0.0013 436-494 / 10-65
PF09182.9 Bacterial purine repressor, N-terminal 0.0013 435-489 / 7-68
PF12840.6 Helix-turn-helix domain 0.0013 432-480 / 8-54
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.0015 430-487 / 6-63
PF02082.19 Transcriptional regulator 0.0016 436-492 / 12-69
PF01726.15 LexA DNA binding domain 0.0018 446-480 / 25-60
PF01047.21 MarR family 0.0019 435-481 / 6-52
PF05158.11 RNA polymerase Rpc34 subunit 0.002 429-481 / 89-143
PF04703.11 FaeA-like protein 0.002 437-480 / 5-48
PF12802.6 MarR family 0.002 435-480 / 8-55
PF11972.7 HTH DNA binding domain 0.0021 437-488 / 4-52
PF01022.19 Bacterial regulatory protein, arsR family 0.0029 436-476 / 6-46
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.0033 448-480 / 13-48
PF09339.9 IclR helix-turn-helix domain 0.0033 437-479 / 8-51
PF13412.5 Winged helix-turn-helix DNA-binding 0.0034 437-476 / 8-47
PF03297.14 S25 ribosomal protein 0.0041 436-480 / 46-90
PF14338.5 Mrr N-terminal domain 0.0049 435-498 / 21-86
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0061 437-479 / 7-50
PF08220.11 DeoR-like helix-turn-helix domain 0.0074 437-480 / 5-48

Annotations of the NCBI proteins of this PHROG


1:ATP-dependent DNA helicase 1:hypothetical protein 1:RecG-like DNA helicase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K03655 recG : ATP-dependent DNA helicase RecG [EC:3.6.4.12] ko03440 Homologous recombination 792 5

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0009378 four-way junction helicase activity
GO:0007131 reciprocal meiotic recombination
GO:0009289 pilus
GO:0005622 intracellular
GO:0006260 DNA replication
GO:0006383 transcription by RNA polymerase III
GO:0004674 protein serine/threonine kinase activity
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005840 ribosome
GO:0006274 DNA replication termination
GO:0003700 DNA binding transcription factor activity
GO:0006468 protein phosphorylation
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006355 regulation of transcription, DNA-templated
GO:0051304 chromosome separation
GO:0006412 translation
GO:0006525 arginine metabolic process
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0004252 serine-type endopeptidase activity
GO:0006281 DNA repair
GO:0005524 ATP binding
GO:0006276 plasmid maintenance
GO:0006508 proteolysis
GO:0005666 DNA-directed RNA polymerase III complex

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