phrog_12258 is made of 8 protein sequences and is annotated as "HTH DNA binding protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
124.62 136 123


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KU737346_p274 AMW62024.1 helix-turn-helix DNA binding protein KU737346 Bacillus phage Vinny Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bastillevirus; unclassified Bastillevirus.
NC_024207_p272 YP_009035793.1 hypothetical protein NC_024207 Bacillus phage Evoli Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bastillevirus; Bacillus virus Evoli.
MF498901_p273 ASU01120.1 hypothetical protein MF498901 Bacillus phage Anthony Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bastillevirus; unclassified Bastillevirus.
MF288922_p266 ASR79896.1 helix-turn-helix DNA binding protein MF288922 Bacillus phage Janet Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bastillevirus; unclassified Bastillevirus.
NC_024216_p265 YP_009037168.1 helix-turn-helix binding domain protein NC_024216 Bacillus phage CAM003 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bastillevirus.
NC_024205_p251 YP_009035448.1 helix-turn-helix binding domain protein NC_024205 Bacillus phage Hoody T Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bastillevirus; Bacillus virus HoodyT.
NC_018856_p208 YP_006907496.1 DNA binding protein NC_018856 Bacillus phage Bastille Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bastillevirus.
MF288921_p270 ASR79420.1 hypothetical protein MF288921 Bacillus phage OTooleKemple52 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bastillevirus; unclassified Bastillevirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_13981 7 no annotation unknown function 5 7.59E-29 19.24
phrog_15423 6 no annotation unknown function 4 5.33E-24 14.4
phrog_4520 30 no annotation unknown function 3 1.82E-15 5.86
phrog_6602 18 no annotation unknown function 2 3.76E-12 2.55

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1373 transcriptional regulator transcription regulation 91.5 0.033 19-77 / 36-90
phrog_25914 HTH DNA binding protein DNA, RNA and nucleotide metabolism 98.7 9.2E-12 7-84 / 6-91
phrog_4221 replication initiation protein DNA, RNA and nucleotide metabolism 90.5 0.053 95-118 / 262-285
phrog_8 transcriptional regulator transcription regulation 93.8 0.007 35-83 / 17-64

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13744.5 Helix-turn-helix domain 4.1E-07 27-91 / 15-79
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 1.8E-06 28-93 / 8-78
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 2.1E-06 42-95 / 10-62
PF01381.21 Helix-turn-helix 4E-06 39-89 / 5-54
PF12844.6 Helix-turn-helix domain 8.6E-06 41-93 / 10-61
PF05339.10 Protein of unknown function (DUF739) 1.1E-05 36-91 / 9-63
PF14590.5 Domain of unknown function (DUF4447) 1.7E-05 32-93 / 9-72
PF13413.5 Helix-turn-helix domain 1.8E-05 39-88 / 5-59
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 3.3E-05 35-92 / 74-129
PF13560.5 Helix-turn-helix domain 4.7E-05 34-90 / 5-63
PF08667.9 BetR domain 5.1E-05 33-94 / 8-72
PF04645.11 Protein of unknown function, DUF603 5.4E-05 29-91 / 6-67
PF13443.5 Cro/C1-type HTH DNA-binding domain 8.8E-05 46-93 / 13-62
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.00018 46-93 / 10-57
PF05269.10 Bacteriophage CII protein 0.0002 41-94 / 21-71
PF08965.9 Domain of unknown function (DUF1870) 0.00033 34-92 / 5-67
PF13693.5 Winged helix-turn-helix DNA-binding 0.0004 37-93 / 9-61
PF00356.20 Bacterial regulatory proteins, lacI family 0.0015 47-73 / 2-28
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0017 36-82 / 119-164
PF12116.7 Stage III sporulation protein D 0.0022 43-85 / 19-61
PF02376.14 CUT domain 0.0042 32-94 / 9-69
PF14549.5 DNA-binding transcriptional regulator Cro 0.0055 46-90 / 11-52
PF10654.8 Protein of unknown function (DUF2481) 0.0071 41-69 / 78-105

Annotations of the NCBI proteins of this PHROG


3:hypothetical protein 2:helix-turn-helix binding domain protein 2:helix-turn-helix DNA binding protein 1:DNA binding protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0043565 sequence-specific DNA binding
GO:0003677 DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0005634 nucleus

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