phrog_12324 is made of 8 protein sequences and is annotated as "intron-like DNA endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
268.88 269 269


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_025419_p225 YP_009098611.1 homing endonuclease NC_025419 Enterobacteria phage RB3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_019500_p178 YP_007004219.1 I-TevIII NC_019500 Enterobacteria phage Bp7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Dhakavirus.
NC_031011_p52 YP_009278950.1 homing endonuclease NC_031011 Shigella phage SHFML-26 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_030953_p130 YP_009277600.1 homing endonuclease NC_030953 Shigella phage SHFML-11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_024125_p231 YP_009030836.1 Intron-associated endonuclease 3 NC_024125 Escherichia phage vB_EcoM_112 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_020416_p220 YP_007501259.1 hypothetical protein NC_020416 Salmonella phage vB_SenMS16 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Gelderlandvirus.
NC_027353_p233 YP_009149472.1 hypothetical protein NC_027353 Yersinia phage phiD1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_031047_p238 YP_009284233.1 putative intron-associated endonuclease 3 NC_031047 Escherichia phage HY03 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Escherichia virus HY03.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_10582 10 ribonucleotide reductase class Ia beta subunit DNA, RNA and nucleotide metabolism 7 5.42E-38 28.39
phrog_8368 13 aerobic NDP reductase small subunit DNA, RNA and nucleotide metabolism 6 2.07E-31 21.81

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_14808 no annotation unknown function 93.3 0.01 204-253 / 13-58
phrog_14913 HNH endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0053 23-56 / 59-92
phrog_15471 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.5E-05 4-81 / 36-105
phrog_1891 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.4E-06 4-83 / 125-187
phrog_27406 endonuclease DNA, RNA and nucleotide metabolism 100.0 2.1E-73 173-269 / 1-97
phrog_4578 HNH endonuclease DNA, RNA and nucleotide metabolism 91.4 0.035 10-43 / 2-30
phrog_59 HNH endonuclease DNA, RNA and nucleotide metabolism 93.4 0.0098 22-50 / 70-98
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 91.9 0.026 23-57 / 103-137
phrog_99 HNH endonuclease DNA, RNA and nucleotide metabolism 93.1 0.012 3-47 / 54-92

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF06524.11 NOA36 protein 7.9E-05 163-268 / 19-137
PF13392.5 HNH endonuclease 5.6E-11 1-49 / 2-44
PF05551.10 Zinc-binding loop region of homing endonuclease 1.9E-09 1-55 / 30-82
PF17017.4 Aberrant zinc-finger 8.1E-08 156-257 / 1-157
PF15909.4 C2H2-type zinc ribbon 0.00087 182-257 / 3-84
PF12756.6 C2H2 type zinc-finger (2 copies) 0.00077 156-234 / 2-77
PF09845.8 Zn-ribbon containing protein 0.0014 239-267 / 1-29
PF08274.11 PhnA Zinc-Ribbon 0.0017 239-267 / 2-29
PF16622.4 zinc-finger C2H2-type 0.0025 154-179 / 3-28
PF01780.18 Ribosomal L37ae protein family 0.0027 239-268 / 33-62
PF12171.7 Zinc-finger double-stranded RNA-binding 0.003 156-178 / 1-23
PF03966.15 Trm112p-like protein 0.0072 239-267 / 7-35
PF13717.5 zinc-ribbon domain 0.0075 257-267 / 26-36
PF14803.5 Nudix N-terminal 0.0079 242-267 / 3-32
PF13719.5 zinc-ribbon domain 0.0083 210-220 / 4-14

Annotations of the NCBI proteins of this PHROG


3:homing endonuclease 2:hypothetical protein 1:Intron-associated endonuclease 3 1:intron-associated endonuclease 3 1:I-TevIII

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005622 intracellular
GO:0003735 structural constituent of ribosome
GO:0005840 ribosome
GO:0006412 translation
GO:0005634 nucleus
GO:0008270 zinc ion binding

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