phrog_12400 is made of 8 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
157 157 157


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF155946_p36 ASR75444.1 HNH endonuclease MF155946 Streptomyces phage Mildred21 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Mildred21.
MF347637_p32 ASR77523.1 HNH endonuclease MF347637 Streptomyces phage Paradiddles Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Paradiddles.
MF358541_p40 ASN73115.1 HNH endonuclease MF358541 Streptomyces phage Warpy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; unclassified Samistivirus.
MF347638_p37 ASR77744.1 HNH endonuclease MF347638 Streptomyces phage Peebs Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Peebs.
MF358542_p38 ASR76471.1 HNH endonuclease MF358542 Streptomyces phage Sushi23 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; unclassified Samistivirus.
MF347639_p37 AST15269.1 HNH endonuclease MF347639 Streptomyces phage Samisti12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Samisti12.
MF347636_p32 ASR77302.1 HNH endonuclease MF347636 Streptomyces phage NootNoot Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus NootNoot.
NC_029098_p40 YP_009225766.1 HNH endonuclease NC_029098 Streptomyces phage Jay2Jay Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Jay2Jay.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_12661 8 transglycosylase other 8 0 1000
phrog_16010 6 glycosyltransferase moron, auxiliary metabolic gene and host takeover 5 1.08E-29 20.09
phrog_8533 13 no annotation unknown function 3 4.76E-17 7.44

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 98.2 1.1E-09 23-91 / 95-157
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.4E-06 13-87 / 131-200
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 91.7 0.03 19-88 / 52-114
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 4.1E-05 17-112 / 68-159
phrog_17283 HNH endonuclease DNA, RNA and nucleotide metabolism 96.5 2.9E-05 43-89 / 1-45
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 91.9 0.027 20-89 / 7-76
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 1.9E-06 21-87 / 27-80
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 99.1 4.5E-14 25-91 / 24-87
phrog_4581 terminase small subunit head and packaging 92.9 0.014 14-84 / 44-105
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 98.2 1.5E-09 20-101 / 14-85
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 95.1 0.0013 18-89 / 39-101
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 95.9 0.00019 31-87 / 7-54
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 97.5 2.2E-07 20-92 / 101-160

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05315.10 ICEA Protein 5.6E-10 15-87 / 79-150
PF05766.11 Bacteriophage Lambda NinG protein 1.5E-09 15-87 / 72-136
PF13395.5 HNH endonuclease 5E-09 32-87 / 1-51
PF01844.22 HNH endonuclease 9.2E-09 32-86 / 1-47
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 2.5E-08 29-119 / 253-328
PF13391.5 HNH endonuclease 1.2E-07 32-87 / 1-45
PF06147.10 Protein of unknown function (DUF968) 4.1E-07 28-87 / 126-174
PF16784.4 Putative HNHc nuclease 0.00015 29-87 / 123-171

Annotations of the NCBI proteins of this PHROG


8:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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