phrog_12434 is made of 8 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
287.5 295 292


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY942057_p173 ASD51559.1 hypothetical protein KY942057 Dickeya phage XF4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; unclassified Limestonevirus.
KU160494_p91 ALY07087.1 hypothetical protein KU160494 Vibrio phage vB_VmeM-32 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; unclassified Tevenvirinae.
KY942056_p177 ASD51364.1 hypothetical protein KY942056 Dickeya phage JA15 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; unclassified Limestonevirus.
NC_025452_p141 YP_009102981.1 hypothetical protein NC_025452 Dickeya phage RC-2014 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus.
MG266157_p176 ATW62180.1 putative HNH endonuclease MG266157 Dickeya phage PP35 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; unclassified Limestonevirus.
KM209228_p174 AIM51389.1 hypothetical protein KM209228 Dickeya phage phiD3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; Dickeya virus Limestone.
KY683735_p27 ASJ80121.1 hypothetical protein KY683735 Escherichia phage ECD7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Krischvirus; Escherichia virus ECD7.
NC_019925_p179 YP_007237501.1 putative intron I-LimII NC_019925 Dickeya virus Limestone Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2062 73 DNA polymerase DNA, RNA and nucleotide metabolism 7 1.62E-29 19.91
phrog_15725 6 DNA polymerase DNA, RNA and nucleotide metabolism 5 1.08E-29 20.09

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10088 homing endonuclease DNA, RNA and nucleotide metabolism 93.6 0.0078 23-77 / 7-62
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 93.0 0.013 26-74 / 33-83
phrog_655 homing endonuclease DNA, RNA and nucleotide metabolism 99.6 3.3E-19 22-135 / 6-136

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF07460.10 NUMOD3 motif (2 copies) 4.2E-08 202-238 / 1-37
PF13395.5 HNH endonuclease 1.9E-07 24-73 / 1-51
PF01844.22 HNH endonuclease 4.8E-07 24-71 / 1-46
PF14279.5 HNH endonuclease 1.4E-06 24-74 / 1-46
PF13391.5 HNH endonuclease 1.5E-06 24-75 / 1-47
PF05766.11 Bacteriophage Lambda NinG protein 1.6E-06 4-74 / 77-137
PF05315.10 ICEA Protein 1.7E-06 3-74 / 83-151
PF06147.10 Protein of unknown function (DUF968) 3.6E-05 23-73 / 129-174
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.0001 22-75 / 254-298
PF16784.4 Putative HNHc nuclease 0.0016 23-73 / 125-171

Annotations of the NCBI proteins of this PHROG


6:hypothetical protein 1:HNH endonuclease 1:intron I-LimII

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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