phrog_12576 is made of 8 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
231.88 244 244


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_019405_p198 YP_006988094.1 putative HNH endonuclease NC_019405 Caulobacter virus phiCbK Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus.
KY555144_p202 ARB14420.1 hypothetical protein KY555144 Caulobacter phage Ccr5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus; unclassified Shapirovirus.
KY555143_p204 ARB14078.1 hypothetical protein KY555143 Caulobacter phage Ccr2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus; unclassified Shapirovirus.
NC_019411_p204 YP_006989937.1 putative HNH endonuclease NC_019411 Caulobacter virus Swift Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus.
NC_019410_p209 YP_006989589.1 putative HNH endonuclease NC_019410 Caulobacter virus Karma Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus; unclassified Shapirovirus.
NC_019407_p205 YP_006988887.1 putative HNH endonuclease NC_019407 Caulobacter virus Magneto Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus; unclassified Shapirovirus.
NC_019408_p204 YP_006989233.1 putative HNH endonuclease NC_019408 Caulobacter virus Rogue Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Phicbkvirus.
KY555145_p209 ARB14767.1 hypothetical protein KY555145 Caulobacter phage Ccr29 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus; unclassified Shapirovirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_12977 8 no annotation unknown function 8 0 1000
phrog_14581 7 no annotation unknown function 7 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 95.4 0.00069 24-100 / 97-163
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00035 27-92 / 15-67
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 94.4 0.0036 20-90 / 54-114
phrog_15463 HNH endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0022 23-122 / 126-210
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00014 18-95 / 70-136
phrog_16986 no annotation unknown function 90.1 0.061 20-102 / 12-83
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 4.4E-08 19-99 / 7-83
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 4.3E-08 19-89 / 26-80
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 95.8 0.00028 11-92 / 11-76
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 95.4 0.00077 24-95 / 24-89
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 98.1 4.7E-09 16-89 / 11-71
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 95.6 0.00051 20-90 / 42-100
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 8.9E-05 52-89 / 17-54
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.3E-06 27-89 / 67-112
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 5.9E-05 20-91 / 102-157
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 98.5 9.2E-11 17-113 / 99-190

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05315.10 ICEA Protein 1.8E-07 13-89 / 78-150
PF13395.5 HNH endonuclease 2.4E-07 31-89 / 1-51
PF01844.22 HNH endonuclease 1.2E-06 56-88 / 12-47
PF14279.5 HNH endonuclease 1.4E-06 31-91 / 1-47
PF05766.11 Bacteriophage Lambda NinG protein 5.3E-06 16-89 / 74-136
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 2.3E-05 55-93 / 263-300
PF13391.5 HNH endonuclease 3.3E-05 55-88 / 11-44
PF06147.10 Protein of unknown function (DUF968) 0.00038 27-88 / 126-173

Annotations of the NCBI proteins of this PHROG


5:HNH endonuclease 3:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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