phrog_12817 is made of 8 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
140.5 162 158


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY579375_p12 AQQ16870.1 ORF18 KY579375 Sulfolobus spindle-shaped virus 3 Viruses; Fuselloviridae; Alphafusellovirus; unclassified Alphafusellovirus.
p388695 no NCBI prot ID no annotation VI_04039 Thermoprotei_gi_227829020_118353_133781 Viruses; Fuselloviridae.
NC_009986_p20 YP_001552198.1 putative transcription regulator MarR family NC_009986 Sulfolobus spindle-shaped virus 4 (SSV4) Viruses; Fuselloviridae; Alphafusellovirus.
NC_005360_p13 NP_963938.1 ORF E150 NC_005360 Sulfolobus virus Ragged Hills Viruses; Fuselloviridae; Alphafusellovirus.
NC_011217_p20 YP_002221485.1 MarR family NC_011217 Sulfolobus spindle-shaped virus 5 (SSV5) Viruses; Fuselloviridae; Alphafusellovirus.
KY563228_p17 AQQ16836.1 D154 KY563228 Sulfolobus spindle-shaped virus Lassen Viruses; Fuselloviridae; Alphafusellovirus; unclassified Alphafusellovirus.
p395706 no NCBI prot ID no annotation VI_04040 Thermoprotei_gi_227826411_1679190_1693805 Viruses; Fuselloviridae.
NC_005265_p11 NP_944463.1 ORF 106 NC_005265 Sulfolobus spindle-shaped virus 2 Viruses; Fuselloviridae; Alphafusellovirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_582 238 Arc-like repressor transcription regulation 6 9.45E-22 12.15
phrog_26550 3 no annotation unknown function 3 0 1000
phrog_29126 2 no annotation unknown function 2 0 1000
phrog_11638 9 no annotation unknown function 2 3.87E-13 3.53

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11046 transcriptional regulator transcription regulation 96.4 4.5E-05 64-139 / 8-84
phrog_11195 no annotation unknown function 94.5 0.0032 70-135 / 27-96
phrog_2440 transcriptional regulator transcription regulation 94.5 0.003 68-132 / 14-75
phrog_4278 no annotation unknown function 91.5 0.033 67-134 / 16-88
phrog_9665 transcriptional regulator transcription regulation 94.0 0.0056 38-140 / 9-117

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF11313.7 Protein of unknown function (DUF3116) 5.2E-08 81-149 / 10-83
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 5.8E-08 77-147 / 7-92
PF14557.5 Putative AphA-like transcriptional regulator 1.3E-07 75-150 / 5-92
PF09114.9 Transcription factor MotA, activation domain 1.6E-07 75-153 / 13-86
PF04079.15 Segregation and condensation complex subunit ScpB 1.8E-07 73-146 / 78-150
PF02334.15 Replication terminator protein 2.4E-07 81-152 / 21-107
PF01090.18 Ribosomal protein S19e 3.2E-07 80-150 / 53-137
PF14277.5 Domain of unknown function (DUF4364) 3.9E-07 82-149 / 4-74
PF07381.10 Winged helix DNA-binding domain (DUF1495) 5.3E-07 77-145 / 8-88
PF13601.5 Winged helix DNA-binding domain 5.2E-07 82-152 / 4-76
PF03965.15 Penicillinase repressor 7.7E-07 78-142 / 3-71
PF14394.5 Domain of unknown function (DUF4423) 8.4E-07 77-147 / 20-91
PF05584.10 Sulfolobus plasmid regulatory protein 8.8E-07 77-143 / 5-70
PF03551.13 Transcriptional regulator PadR-like family 1.2E-06 91-146 / 13-73
PF14947.5 Winged helix-turn-helix 1.5E-06 81-150 / 5-73
PF09639.9 YjcQ protein 1.6E-06 91-150 / 15-85
PF04492.12 Bacteriophage replication protein O 1.7E-06 75-125 / 24-82
PF01638.16 HxlR-like helix-turn-helix 2.8E-06 80-150 / 7-79
PF02002.16 TFIIE alpha subunit 2.8E-06 79-150 / 13-86
PF10711.8 Hypothetical protein (DUF2513) 2.9E-06 81-149 / 8-86
PF13463.5 Winged helix DNA-binding domain 2.9E-06 79-141 / 4-67
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 3.2E-06 76-149 / 3-81
PF12793.6 Sugar transport-related sRNA regulator N-term 3.2E-06 82-150 / 6-77
PF05732.10 Firmicute plasmid replication protein (RepL) 4.1E-06 75-150 / 51-148
PF09202.10 Rio2, N-terminal 4.7E-06 77-146 / 5-75
PF01978.18 Sugar-specific transcriptional regulator TrmB 1.1E-05 76-125 / 6-55
PF03428.12 Replication protein C N-terminal domain 1.6E-05 71-126 / 36-105
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 1.6E-05 77-145 / 7-73
PF02319.19 E2F/DP family winged-helix DNA-binding domain 1.6E-05 82-125 / 11-56
PF02295.16 Adenosine deaminase z-alpha domain 1.7E-05 80-125 / 6-52
PF16221.4 winged helix-turn-helix 1.8E-05 79-124 / 32-78
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 1.8E-05 91-147 / 23-76
PF01475.18 Ferric uptake regulator family 2.2E-05 76-139 / 5-73
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 2.6E-05 77-125 / 12-60
PF08222.10 CodY helix-turn-helix domain 2.7E-05 91-125 / 3-37
PF07848.11 PaaX-like protein 2.8E-05 91-141 / 19-70
PF09904.8 Winged helix-turn helix 2.9E-05 81-142 / 10-74
PF08461.9 Ribonuclease R winged-helix domain 3.3E-05 86-144 / 6-64
PF09012.9 FeoC like transcriptional regulator 4.4E-05 85-126 / 7-48
PF04358.12 DsrC like protein 5E-05 74-125 / 35-94
PF06163.10 Bacterial protein of unknown function (DUF977) 4.9E-05 78-126 / 12-60
PF04703.11 FaeA-like protein 5.1E-05 83-126 / 5-48
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 6E-05 82-126 / 5-52
PF12802.6 MarR family 6.6E-05 80-126 / 7-55
PF05158.11 RNA polymerase Rpc34 subunit 7.3E-05 75-127 / 89-143
PF04182.11 B-block binding subunit of TFIIIC 8.7E-05 81-126 / 5-52
PF01047.21 MarR family 0.0001 81-126 / 6-51
PF06969.15 HemN C-terminal domain 0.0001 83-142 / 11-65
PF16864.4 Dimerisation domain 0.00012 79-146 / 19-80
PF08784.10 Replication protein A C terminal 0.00013 77-125 / 39-94
PF01726.15 LexA DNA binding domain 0.00013 92-126 / 25-60
PF01316.20 Arginine repressor, DNA binding domain 0.00013 79-140 / 6-67
PF02082.19 Transcriptional regulator 0.00015 81-125 / 11-57
PF07183.10 Protein of unknown function (DUF1403) 0.00016 79-125 / 275-319
PF09182.9 Bacterial purine repressor, N-terminal 0.00019 80-125 / 6-58
PF13412.5 Winged helix-turn-helix DNA-binding 0.00019 83-122 / 8-47
PF13034.5 Protein of unknown function (DUF3895) 0.00022 79-126 / 4-67
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.00025 77-125 / 7-55
PF01022.19 Bacterial regulatory protein, arsR family 0.00025 83-122 / 7-46
PF14338.5 Mrr N-terminal domain 0.00031 81-146 / 21-86
PF09824.8 ArsR transcriptional regulator 0.00036 77-125 / 16-61
PF09339.9 IclR helix-turn-helix domain 0.00037 83-125 / 8-51
PF12840.6 Helix-turn-helix domain 0.00038 77-125 / 7-53
PF11972.7 HTH DNA binding domain 0.0006 84-122 / 5-40
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00061 94-125 / 13-47
PF08535.9 KorB domain 0.00082 92-145 / 3-59
PF03297.14 S25 ribosomal protein 0.00092 82-125 / 46-89
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.00094 91-125 / 16-50
PF08220.11 DeoR-like helix-turn-helix domain 0.0012 84-125 / 6-47
PF13730.5 Helix-turn-helix domain 0.0017 103-122 / 33-52
PF01418.16 Helix-turn-helix domain, rpiR family 0.002 77-125 / 15-67
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.002 91-125 / 20-54
PF00392.20 Bacterial regulatory proteins, gntR family 0.0025 91-125 / 22-57
PF07900.10 Protein of unknown function (DUF1670) 0.0028 91-126 / 94-129
PF14502.5 Helix-turn-helix domain 0.0031 92-125 / 6-39
PF05331.10 Protein of unknown function (DUF742) 0.0035 77-125 / 40-86
PF16509.4 TrfB plasmid transcriptional repressor 0.0033 91-144 / 30-84
PF09821.8 C-terminal AAA-associated domain 0.0044 97-146 / 2-45
PF15977.4 Winged helix-turn-helix DNA binding 0.0045 92-125 / 23-56
PF13404.5 AsnC-type helix-turn-helix domain 0.0046 83-116 / 8-41
PF09397.9 Ftsk gamma domain 0.0055 84-125 / 11-52
PF07037.10 Putative transcription regulator (DUF1323) 0.0058 94-149 / 2-56
PF09756.8 DDRGK domain 0.0071 83-141 / 106-162
PF13545.5 Crp-like helix-turn-helix domain 0.0075 91-125 / 26-60
PF05043.12 Mga helix-turn-helix domain 0.0079 78-119 / 16-57

Annotations of the NCBI proteins of this PHROG


4:hypothetical protein 1:MarR family 1:transcription regulator MarR family

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006355 regulation of transcription, DNA-templated
GO:0051304 chromosome separation
GO:0006525 arginine metabolic process
GO:0006412 translation
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0004252 serine-type endopeptidase activity
GO:0006281 DNA repair
GO:0005524 ATP binding
GO:0006276 plasmid maintenance
GO:0006508 proteolysis
GO:0005666 DNA-directed RNA polymerase III complex
GO:0043565 sequence-specific DNA binding
GO:0009378 four-way junction helicase activity
GO:0007131 reciprocal meiotic recombination
GO:0005622 intracellular
GO:0006383 transcription by RNA polymerase III
GO:0006260 DNA replication
GO:0009289 pilus
GO:0004674 protein serine/threonine kinase activity
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005840 ribosome
GO:0006274 DNA replication termination
GO:0003700 DNA binding transcription factor activity
GO:0006468 protein phosphorylation
GO:0006310 DNA recombination
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0003677 DNA binding

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