phrog_1309 is made of 114 protein sequences and is annotated as "endolysin"
Functional category: lysis


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
374.43 629 400


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_009018_p56 YP_001039943.1 phage-associated cell wall hydrolase NC_009018 Streptococcus phage phi3396 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p370798 no NCBI prot ID no annotation VI_00760 Bacilli_gi_50913346_1546623_1564006 Viruses.
KC348599_p11 AGF87355.1 putative lysin KC348599 Streptococcus phage phi30c Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KC348598_p2 AGF87292.1 putative phage lysin KC348598 Streptococcus phage phi20c Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_027120_p22 YP_009140409.1 endolysin NC_027120 Lactococcus phage 1358 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p89297 no NCBI prot ID no annotation VI_05395 Bacilli_gi_553746122_21701_68199 Viruses.
NC_018285_p6 YP_006561227.1 phage-associated cell wall hydrolase NC_018285 Streptococcus phage YMC-2011 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Moineauvirus; unclassified Moineauvirus.
p89030 no NCBI prot ID no annotation VI_00747 Bacilli_gi_19745201_1041255_1087764 Viruses.
NC_019418_p3 YP_006990322.1 putative phage amidase protein NC_019418 Streptococcus phage phiNJ2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p99225 no NCBI prot ID no annotation VI_00976 Bacilli_gi_386361880_967175_1012375 Viruses.
KC413988_p1 AGE61206.1 putative phage lysin KC413988 Streptococcus phage phiST1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p384964 no NCBI prot ID no annotation VI_05399 Bacilli_gi_553746535 Viruses; unclassified bacterial viruses.
p350175 no NCBI prot ID no annotation VI_05356 Bacilli_gi_544931225 Viruses.
p214455 no NCBI prot ID no annotation VI_04581 Bacilli_gi_417939277_5553_40816 Viruses.
p94588 no NCBI prot ID no annotation VI_00468 Bacilli_gi_448879149_252108_297819 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p252552 no NCBI prot ID no annotation VI_04365 Bacilli_gi_56808948 Viruses; unclassified bacterial viruses.
p342675 no NCBI prot ID no annotation VI_05383 Bacilli_gi_553744317 Viruses.
NC_004589_p48 NP_795707.1 putative cell wall hydrolase, lysin NC_004589 Streptococcus phage 315.6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_004588_p49 NP_795653.1 putative cell wall hydrolase, lysin NC_004588 Streptococcus phage 315.5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p182135 no NCBI prot ID no annotation VI_00755 Bacilli_gi_28894912_545611_583628 Viruses; unclassified bacterial viruses.
p287821 no NCBI prot ID no annotation VI_04559 Bacilli_gi_417752159_1026_28537 Viruses.
p135827 no NCBI prot ID no annotation VI_00115 Bacilli_gi_545645907 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p181976 no NCBI prot ID no annotation VI_00751 Bacilli_gi_21909536_1313257_1351275 Viruses; unclassified bacterial viruses.
p260082 no NCBI prot ID no annotation VI_05344 Bacilli_gi_544867302 Viruses; unclassified bacterial viruses.
p184502 no NCBI prot ID no annotation VI_00118 Bacilli_gi_523414886_1002676_1040469 Viruses; unclassified bacterial viruses.
p184622 no NCBI prot ID no annotation VI_00847 Bacilli_gi_409913960_982600_1020388 Viruses; unclassified bacterial viruses.
NC_028700_p60 YP_009191729.1 lysin NC_028700 Streptococcus phage T12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p184562 no NCBI prot ID no annotation VI_00985 Bacilli_gi_71909814_983899_1021692 Viruses; unclassified bacterial viruses.
p211621 no NCBI prot ID no annotation VI_04580 Bacilli_gi_417935460_55324_90986 Viruses.
p300765 no NCBI prot ID no annotation VI_04364 Bacilli_gi_223933546 Viruses.
KC348602_p2 AGF87539.1 putative phage lysin KC348602 Streptococcus phage phi891591 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KC413987_p1 AGE61150.1 putative phage lysin KC413987 Streptococcus phage phiSS12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KC348601_p2 AGF87477.1 putative phage lysin KC348601 Streptococcus phage phi7917 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_003157_p51 NP_438163.1 cell wall hydrolase NC_003157 Temperate phage phiNIH1.1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p296864 no NCBI prot ID no annotation VI_05087 Bacilli_gi_481025945 Viruses.
p184132 no NCBI prot ID no annotation VI_00438 Bacilli_gi_422757969_1394223_1432038 Viruses.
p156099 no NCBI prot ID no annotation VI_00987 Bacilli_gi_94987631_1380189_1420438 Viruses.
p264218 no NCBI prot ID no annotation VI_05413 Bacilli_gi_545669324_94008_124660 Viruses.
p87209 no NCBI prot ID no annotation VI_00892 Bacilli_gi_525808973_964189_1010999 Viruses; unclassified bacterial viruses.
p197611 no NCBI prot ID no annotation VI_00776 Bacilli_gi_139472888_1271278_1308146 Viruses; unclassified bacterial viruses.
p137445 no NCBI prot ID no annotation VI_05411 Bacilli_gi_560295271_60173_102174 Viruses; unclassified bacterial viruses.
p142356 no NCBI prot ID no annotation VI_00752 Bacilli_gi_21909536_1230279_1271840 Viruses; unclassified bacterial viruses.
p156252 no NCBI prot ID no annotation VI_00846 Bacilli_gi_409913960_1385758_1426006 Viruses.
p264367 no NCBI prot ID no annotation VI_05387 Bacilli_gi_553744498_158659_189280 Viruses; unclassified bacterial viruses.
p233677 no NCBI prot ID no annotation VI_00798 Bacilli_gi_225869487_1742324_1775791 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p136854 no NCBI prot ID no annotation VI_00994 Bacilli_gi_94989509_528607_570690 Viruses; unclassified bacterial viruses.
p241597 no NCBI prot ID no annotation VI_05390 Bacilli_gi_553744818_158638_191344 Viruses; unclassified bacterial viruses.
p164636 no NCBI prot ID no annotation VI_05403 Bacilli_gi_560277320_21734_61260 Viruses; unclassified bacterial viruses.
p325527 no NCBI prot ID no annotation VI_04536 Bacilli_gi_357238483_407714_430480 Viruses.
p169237 no NCBI prot ID no annotation VI_00744 Bacilli_gi_19745201_578068_617146 Viruses; unclassified bacterial viruses.
p167187 no NCBI prot ID no annotation VI_00989 Bacilli_gi_94991497_531482_570812 Viruses.
p141711 no NCBI prot ID no annotation VI_00995 Bacilli_gi_94989509_1254657_1296251 Viruses; unclassified bacterial viruses.
p170786 no NCBI prot ID no annotation VI_00870 Bacilli_gi_15674250_529606_568538 Viruses.
NC_009819_p50 YP_001469230.1 lysin NC_009819 Streptococcus phage P9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p156150 no NCBI prot ID no annotation VI_00990 Bacilli_gi_94991497_1404079_1444328 Viruses.
p165005 no NCBI prot ID no annotation VI_05134 Bacilli_gi_481028301_48_39547 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p156575 no NCBI prot ID no annotation VI_05345 Bacilli_gi_544867478_193_40434 Viruses.
p145986 no NCBI prot ID no annotation VI_04567 Bacilli_gi_417855870_489312_530530 Viruses.
p167358 no NCBI prot ID no annotation VI_00748 Bacilli_gi_21909536_977412_1016695 Viruses; unclassified bacterial viruses.
p139375 no NCBI prot ID no annotation VI_00992 Bacilli_gi_94993396_546006_587868 Viruses; unclassified bacterial viruses.
p156303 no NCBI prot ID no annotation VI_00119 Bacilli_gi_523414886_1404512_1444760 Viruses.
p156201 no NCBI prot ID no annotation VI_00986 Bacilli_gi_71909814_1385736_1425984 Viruses.
p156047 no NCBI prot ID no annotation VI_05409 Bacilli_gi_560293512_94432_134682 Viruses.
p142345 no NCBI prot ID no annotation VI_00753 Bacilli_gi_28894912_625045_666606 Viruses; unclassified bacterial viruses.
NC_004587_p59 NP_795599.1 putative cell wall hydrolase, lysin NC_004587 Streptococcus phage 315.4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p141992 no NCBI prot ID no annotation VI_00745 Bacilli_gi_19745201_1451819_1493398 Viruses; unclassified bacterial viruses.
p163782 no NCBI prot ID no annotation VI_00757 Bacilli_gi_28894912_1107932_1147568 Viruses; unclassified bacterial viruses.
p136860 no NCBI prot ID no annotation VI_00984 Bacilli_gi_71902667_1227073_1269153 Viruses; unclassified bacterial viruses.
p163238 no NCBI prot ID no annotation VI_05412 Bacilli_gi_545669026_54257_93947 Viruses.
p163395 no NCBI prot ID no annotation VI_00762 Bacilli_gi_50913346_35574_75249 Viruses; unclassified bacterial viruses.
p160773 no NCBI prot ID no annotation VI_04926 Bacilli_gi_452726042_108192_148054 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p311475 no NCBI prot ID no annotation VI_00761 Bacilli_gi_50913346_1331436_1355819 Viruses; unclassified bacterial viruses.
p156798 no NCBI prot ID no annotation VI_00437 Bacilli_gi_306828415 Viruses; unclassified bacterial viruses.
p170137 no NCBI prot ID no annotation VI_00749 Bacilli_gi_21909536_749188_788201 Viruses; unclassified bacterial viruses.
p171334 no NCBI prot ID no annotation VI_00756 Bacilli_gi_28894912_880188_919089 Viruses; unclassified bacterial viruses.
NC_004584_p51 NP_795423.1 putative cell wall amidase NC_004584 Streptococcus phage 315.1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_004585_p57 NP_795485.1 putative cell wall hydrolase NC_004585 Streptococcus phage 315.2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p156522 no NCBI prot ID no annotation VI_05361 Bacilli_gi_544932303_149338_189585 Viruses.
p247322 no NCBI prot ID no annotation VI_05402 Bacilli_gi_560274507_0_32071 Viruses; unclassified bacterial viruses.
p115933 no NCBI prot ID no annotation VI_05096 Bacilli_gi_481026543_1504_45392 Viruses.
p374717 no NCBI prot ID no annotation VI_04951 Bacilli_gi_452727572 Viruses.
p86324 no NCBI prot ID no annotation VI_05118 Bacilli_gi_481027541 Viruses.
p166871 no NCBI prot ID no annotation VI_04953 Bacilli_gi_452727743 Viruses.
p146629 no NCBI prot ID no annotation VI_05012 Bacilli_gi_452731093_8707_49882 Viruses.
p143637 no NCBI prot ID no annotation VI_05224 Bacilli_gi_481031090_9622_51044 Viruses.
p177613 no NCBI prot ID no annotation VI_05475 Bacilli_gi_470952890 Viruses.
p153618 no NCBI prot ID no annotation VI_05113 Bacilli_gi_481027426 Viruses.
p73862 no NCBI prot ID no annotation VI_05132 Bacilli_gi_481028229 Viruses.
p73591 no NCBI prot ID no annotation VI_05104 Bacilli_gi_481026857 Viruses.
p375103 no NCBI prot ID no annotation VI_05106 Bacilli_gi_481026947 Viruses.
p75962 no NCBI prot ID no annotation VI_05111 Bacilli_gi_481027308 Viruses.
p76955 no NCBI prot ID no annotation VI_04967 Bacilli_gi_452728825 Viruses.
p83467 no NCBI prot ID no annotation VI_05005 Bacilli_gi_452730885 Viruses.
p89981 no NCBI prot ID no annotation VI_04942 Bacilli_gi_452727118 Viruses.
p116010 no NCBI prot ID no annotation VI_04998 Bacilli_gi_452730165_1863_45751 Viruses.
p72391 no NCBI prot ID no annotation VI_05091 Bacilli_gi_481026132 Viruses.
p79436 no NCBI prot ID no annotation VI_05117 Bacilli_gi_481027494 Viruses.
p124227 no NCBI prot ID no annotation VI_05002 Bacilli_gi_452730288_2237_45156 Viruses.
p82126 no NCBI prot ID no annotation VI_04979 Bacilli_gi_452729407 Viruses.
p74167 no NCBI prot ID no annotation VI_05146 Bacilli_gi_481029264 Viruses.
p119757 no NCBI prot ID no annotation VI_04949 Bacilli_gi_452727506_2076_45570 Viruses.
p308508 no NCBI prot ID no annotation VI_04375 Bacilli_gi_77411234_0_24805 Viruses.
p84687 no NCBI prot ID no annotation VI_05222 Bacilli_gi_481030940 Viruses.
p86015 no NCBI prot ID no annotation VI_05016 Bacilli_gi_452731493 Viruses.
p147551 no NCBI prot ID no annotation VI_04952 Bacilli_gi_452727694_2700_43806 Viruses.
p262559 no NCBI prot ID no annotation VI_05291 Bacilli_gi_486409007_0_30736 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p222170 no NCBI prot ID no annotation VI_05129 Bacilli_gi_481028088 Viruses.
p388493 no NCBI prot ID no annotation VI_05144 Bacilli_gi_481029207 Viruses.
p116054 no NCBI prot ID no annotation VI_04972 Bacilli_gi_452729028_1578_45466 Viruses.
p115922 no NCBI prot ID no annotation VI_04955 Bacilli_gi_452728166_2357_46245 Viruses.
p347745 no NCBI prot ID no annotation VI_04930 Bacilli_gi_452726387 Viruses.
p221030 no NCBI prot ID no annotation VI_05108 Bacilli_gi_481027039 Viruses.
p60307 no NCBI prot ID no annotation VI_04969 Bacilli_gi_452728929 Viruses.
p116098 no NCBI prot ID no annotation VI_04970 Bacilli_gi_452728962_1899_45787 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_199 534 holin lysis 35 8.20E-78 68.21
phrog_95 939 integrase integration and excision 32 8.22E-62 52.21
phrog_443 294 holin lysis 24 8.21E-57 47.21
phrog_297 414 holin lysis 23 1.89E-50 40.85
phrog_608 229 holin lysis 17 1.49E-40 30.95
phrog_1281 116 no annotation unknown function 10 3.39E-26 16.59
phrog_10272 10 no annotation unknown function 10 0 1000
phrog_374 335 HNH endonuclease DNA, RNA and nucleotide metabolism 6 1.86E-12 2.85
phrog_6339 19 no annotation unknown function 5 2.84E-18 8.67
phrog_5978 21 no annotation unknown function 4 9.94E-15 5.12
phrog_8049 14 no annotation unknown function 3 2.27E-12 2.77
phrog_16966 5 no annotation unknown function 2 1.05E-10 1.1

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10051 endolysin lysis 98.6 4.1E-11 20-288 / 18-280
phrog_10967 endolysin lysis 99.9 1.2E-29 2-145 / 6-155
phrog_11857 no annotation unknown function 95.1 0.0012 163-298 / 7-154
phrog_12367 endolysin lysis 99.0 1.3E-13 159-391 / 7-239
phrog_12727 endolysin lysis 100.0 8.4E-53 1-145 / 5-154
phrog_13463 endolysin lysis 97.8 3.1E-08 215-400 / 67-336
phrog_18032 endolysin lysis 100.0 6.2E-38 1-178 / 5-196
phrog_22714 no annotation unknown function 95.7 0.00041 156-186 / 9-39
phrog_26675 endolysin lysis 95.1 0.0012 25-137 / 152-283
phrog_2742 endolysin lysis 99.1 1.8E-14 168-280 / 334-455
phrog_28649 no annotation unknown function 90.2 0.06 198-270 / 313-377
phrog_29272 endolysin lysis 92.8 0.016 151-266 / 291-406
phrog_33273 no annotation unknown function 94.8 0.002 322-400 / 3-81
phrog_34646 endolysin lysis 92.3 0.021 162-281 / 331-449
phrog_3513 endolysin lysis 100.0 1.7E-53 1-150 / 4-159
phrog_37633 endolysin lysis 96.6 2.5E-05 168-252 / 12-99
phrog_489 endolysin lysis 99.2 3.4E-15 160-271 / 6-118
phrog_5404 endolysin lysis 99.2 1.3E-14 315-400 / 10-96
phrog_635 endolysin lysis 99.9 1.2E-27 156-400 / 4-460
phrog_7470 amidase lysis 98.1 4.2E-09 162-360 / 5-273
phrog_759 tail associated cell-wall hydrolase other 99.6 1.4E-19 156-306 / 10-153
phrog_7887 endolysin lysis 99.7 7E-22 156-302 / 1-144
phrog_8251 endolysin lysis 99.2 3.2E-15 17-148 / 19-153
phrog_833 endolysin lysis 98.2 2.2E-09 325-400 / 246-320
phrog_8577 endolysin lysis 100.0 3.8E-46 156-301 / 1-154
phrog_8781 endolysin lysis 99.6 2.2E-20 155-270 / 2-119
phrog_9225 no annotation unknown function 92.3 0.021 172-330 / 17-186
phrog_998 endolysin lysis 96.7 1.7E-05 170-286 / 11-149

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01832.19 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 9.2E-12 9-146 / 2-134
PF06940.10 Domain of unknown function (DUF1287) 7.8E-08 176-275 / 59-143
PF12671.6 Putative amidase domain 1.2E-06 170-265 / 4-120
PF06672.10 Protein of unknown function (DUF1175) 5.9E-06 167-207 / 30-67
PF05382.12 Bacteriophage peptidoglycan hydrolase 8E-06 170-264 / 3-103
PF10030.8 Uncharacterized protein conserved in bacteria (DUF2272) 1.7E-05 192-279 / 45-155
PF00877.18 NlpC/P60 family 2.9E-05 182-264 / 2-72
PF08460.9 Bacterial SH3 domain 7.1E-05 338-400 / 2-63
PF05257.15 CHAP domain 0.00018 237-265 / 74-100

Annotations of the NCBI proteins of this PHROG


5:phage lysin 3:cell wall hydrolase, lysin 3:lysin 2:phage-associated cell wall hydrolase 2:cell wall hydrolase 1:phage amidase protein 1:cell wall amidase 1:endolysin

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K01448 E3.5.1.28B, amiA, amiB, amiC : N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] ko01503 Cationic antimicrobial peptide (CAMP) resistance 160 1

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004040 amidase activity

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