phrog_14076 is made of 7 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
87.29 153 69


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p109717 no NCBI prot ID no annotation VI_00077 Alphaproteobacteria_gi_307944653 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p30029 no NCBI prot ID no annotation VI_00108 Alphaproteobacteria_gi_485071565 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Rhizobium phage 16-3.
NC_011103_p99 YP_002117657.1 p099 NC_011103 Rhizobium phage 16-3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_025428_p21 YP_009099678.1 hypothetical protein NC_025428 Ruegeria phage DSS3-P1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_025428_p22 YP_009099679.1 HTH-domain containing protein NC_025428 Ruegeria phage DSS3-P1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p109654 no NCBI prot ID no annotation VI_00077 Alphaproteobacteria_gi_307944653 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_020489_p32 YP_007518414.1 XRE family transcriptional regulator NC_020489 Rhodobacter phage RcapNL Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_14076 7 transcriptional regulator transcription regulation 2 6.34E-14 4.32

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1373 transcriptional regulator transcription regulation 96.7 1.4E-05 4-43 / 34-70
phrog_19114 no annotation unknown function 92.5 0.019 2-53 / 72-120
phrog_2104 no annotation unknown function 97.3 1E-06 1-53 / 45-94
phrog_2328 transcriptional repressor transcription regulation 94.5 0.0029 5-45 / 19-56
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.3 0.0041 6-41 / 29-61
phrog_2439 transcriptional regulator transcription regulation 95.4 0.00077 1-55 / 6-58
phrog_2967 transcriptional regulator transcription regulation 94.5 0.0029 4-43 / 11-48
phrog_3626 no annotation unknown function 94.9 0.0018 1-47 / 10-55
phrog_36984 DNA binding protein DNA, RNA and nucleotide metabolism 90.2 0.059 2-30 / 5-33
phrog_37751 no annotation unknown function 96.8 1E-05 2-46 / 137-180
phrog_3865 no annotation unknown function 92.4 0.021 6-31 / 16-42
phrog_3 transcriptional repressor transcription regulation 95.4 0.00076 3-54 / 5-53
phrog_409 transcriptional regulator transcription regulation 92.6 0.018 1-52 / 1-42
phrog_4739 no annotation unknown function 95.0 0.0014 3-41 / 69-104
phrog_4779 transcriptional regulator transcription regulation 96.3 6.7E-05 1-41 / 1-38
phrog_4836 CII-like regulator transcription regulation 96.5 3.3E-05 6-41 / 87-119
phrog_5119 no annotation unknown function 97.2 1.4E-06 1-58 / 53-107
phrog_5823 transcriptional regulator transcription regulation 94.8 0.0022 3-55 / 6-57
phrog_6499 transcriptional regulator transcription regulation 93.2 0.012 5-56 / 10-65
phrog_7241 transcriptional regulator transcription regulation 94.7 0.0023 6-61 / 66-117
phrog_7950 transcriptional repressor transcription regulation 97.6 1.8E-07 2-43 / 10-48
phrog_8898 no annotation unknown function 96.3 6E-05 1-56 / 1-53
phrog_8 transcriptional regulator transcription regulation 96.2 8.2E-05 3-50 / 3-45
phrog_955 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.9 0.006 2-46 / 37-78

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04936.11 Protein of unknown function (DUF658) 0.0043 18-46 / 87-114
PF08822.10 Protein of unknown function (DUF1804) 1.5E-07 11-104 / 11-103
PF00292.17 'Paired box' domain 4.7E-07 17-47 / 31-60
PF01710.15 Transposase 1.6E-06 17-104 / 16-93
PF13411.5 MerR HTH family regulatory protein 1.9E-06 20-47 / 1-27
PF01381.21 Helix-turn-helix 8.6E-05 16-43 / 6-32
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.004 17-43 / 9-35
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 5.8E-05 6-44 / 10-47
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.0017 17-43 / 8-34
PF13744.5 Helix-turn-helix domain 0.0014 11-43 / 23-54
PF05339.10 Protein of unknown function (DUF739) 0.0021 14-43 / 11-39
PF10654.8 Protein of unknown function (DUF2481) 1.5E-05 14-43 / 75-103
PF05344.10 Domain of Unknown Function (DUF746) 1.7E-05 12-47 / 5-39
PF12844.6 Helix-turn-helix domain 0.0032 17-43 / 10-35
PF13413.5 Helix-turn-helix domain 0.00014 15-43 / 5-32
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 2.7E-05 17-48 / 11-41
PF06322.10 Phage NinH protein 3.3E-05 12-47 / 9-43
PF07141.10 Putative bacteriophage terminase small subunit 3.5E-05 16-46 / 28-57
PF13591.5 MerR HTH family regulatory protein 4.2E-05 20-44 / 1-24
PF07750.10 GcrA cell cycle regulator 6.2E-05 15-46 / 14-45
PF13011.5 leucine-zipper of insertion element IS481 7.5E-05 11-48 / 16-52
PF09607.9 Brinker DNA-binding domain 9.6E-05 20-45 / 26-50
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.0001 71-130 / 76-129
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.0067 20-40 / 9-29
PF15978.4 Tn7-like transposition protein D 0.00012 12-47 / 196-230
PF12759.6 InsA C-terminal domain 0.00013 17-43 / 19-44
PF13560.5 Helix-turn-helix domain 0.005 14-43 / 9-37
PF16087.4 Domain of unknown function (DUF4817) 0.00013 8-48 / 5-52
PF14590.5 Domain of unknown function (DUF4447) 0.0022 9-43 / 10-43
PF08535.9 KorB domain 0.00017 18-47 / 2-30
PF06627.10 Protein of unknown function (DUF1153) 0.00017 11-48 / 38-74
PF13309.5 HTH domain 0.00018 20-40 / 42-62
PF10668.8 Phage terminase small subunit 0.0002 10-47 / 11-49
PF02954.18 Bacterial regulatory protein, Fis family 0.0002 17-40 / 14-37
PF17443.1 Uncharacterized protein pXO2-72 0.00024 17-44 / 6-32
PF05225.15 helix-turn-helix, Psq domain 0.00024 12-44 / 9-41
PF08667.9 BetR domain 0.00024 73-134 / 14-74
PF04552.12 Sigma-54, DNA binding domain 0.00025 16-45 / 45-73
PF02042.14 RWP-RK domain 0.00027 15-46 / 8-38
PF07900.10 Protein of unknown function (DUF1670) 0.00031 17-104 / 93-175
PF14493.5 Helix-turn-helix domain 0.00033 16-48 / 9-40
PF06806.11 Putative excisionase (DUF1233) 0.00033 17-43 / 7-32
PF05269.10 Bacteriophage CII protein 0.00042 75-135 / 21-74
PF08765.10 Mor transcription activator family 0.00042 18-45 / 71-97
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.00044 15-44 / 51-79
PF00356.20 Bacterial regulatory proteins, lacI family 0.0021 79-119 / 1-37
PF00376.22 MerR family regulatory protein 0.00051 21-44 / 1-23
PF13412.5 Winged helix-turn-helix DNA-binding 0.00054 17-45 / 15-42
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 0.00056 17-45 / 17-44
PF04218.12 CENP-B N-terminal DNA-binding domain 0.00057 17-44 / 21-47
PF07453.12 NUMOD1 domain 0.00057 19-40 / 19-40
PF12116.7 Stage III sporulation protein D 0.0024 76-124 / 18-62
PF14549.5 DNA-binding transcriptional regulator Cro 0.0033 17-39 / 8-29
PF11112.7 Pyocin activator protein PrtN 0.0007 18-45 / 12-39
PF08965.9 Domain of unknown function (DUF1870) 0.0027 12-43 / 7-39
PF07825.10 Excisionase-like protein 0.00079 20-46 / 3-30
PF02796.14 Helix-turn-helix domain of resolvase 0.00083 17-40 / 19-42
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.00083 19-42 / 3-25
PF13693.5 Winged helix-turn-helix DNA-binding 0.00086 73-133 / 11-63
PF13518.5 Helix-turn-helix domain 0.00087 18-48 / 10-39
PF05331.10 Protein of unknown function (DUF742) 0.00086 10-46 / 45-79
PF07278.10 Protein of unknown function (DUF1441) 0.00087 19-45 / 1-26
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.00089 18-43 / 26-49
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.00094 19-44 / 107-131
PF01527.19 Transposase 0.00097 12-45 / 14-46
PF16677.4 DNA-packaging protein gp3 0.00096 18-44 / 28-53
PF13556.5 PucR C-terminal helix-turn-helix domain 0.0012 17-46 / 10-38
PF01371.18 Trp repressor protein 0.0012 16-45 / 45-73
PF13936.5 Helix-turn-helix domain 0.0012 17-40 / 18-41
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0012 18-48 / 22-51
PF13404.5 AsnC-type helix-turn-helix domain 0.0013 17-43 / 15-40
PF09035.9 Excisionase from transposon Tn916 0.0013 17-43 / 13-38
PF10743.8 Regulatory phage protein cox 0.0013 17-47 / 9-38
PF07638.10 ECF sigma factor 0.0013 11-43 / 141-172
PF11427.7 Tc3 transposase 0.0014 17-45 / 18-45
PF04645.11 Protein of unknown function, DUF603 0.002 7-45 / 8-48
PF13551.5 Winged helix-turn helix 0.0017 17-48 / 9-39
PF07037.10 Putative transcription regulator (DUF1323) 0.0019 20-43 / 1-23
PF12964.6 Protein of unknown function (DUF3853) 0.0022 18-45 / 44-70
PF13022.5 Helix-turn-helix of insertion element transposase 0.0023 20-42 / 26-47
PF07506.10 RepB plasmid partitioning protein 0.0024 7-44 / 10-45
PF12728.6 Helix-turn-helix domain 0.0027 20-44 / 2-26
PF08281.11 Sigma-70, region 4 0.0028 16-43 / 23-49
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.003 21-40 / 53-72
PF11242.7 Protein of unknown function (DUF2774) 0.003 16-45 / 11-39
PF13171.5 Protein of unknown function (DUF4004) 0.003 20-47 / 3-29
PF16509.4 TrfB plasmid transcriptional repressor 0.0032 14-45 / 26-56
PF00440.22 Bacterial regulatory proteins, tetR family 0.0038 20-40 / 16-36
PF00325.19 Bacterial regulatory proteins, crp family 0.0039 20-44 / 3-26
PF07471.11 Phage DNA packaging protein Nu1 0.0042 19-43 / 2-25
PF10975.7 Protein of unknown function (DUF2802) 0.0046 12-40 / 36-64
PF13384.5 Homeodomain-like domain 0.0048 17-44 / 15-41
PF04545.15 Sigma-70, region 4 0.005 18-40 / 23-45
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0051 11-43 / 118-149
PF02376.14 CUT domain 0.006 6-43 / 7-44
PF08222.10 CodY helix-turn-helix domain 0.0069 18-47 / 3-31
PF06971.12 Putative DNA-binding protein N-terminus 0.0073 19-40 / 27-48
PF08876.10 Domain of unknown function (DUF1836) 0.0074 19-44 / 10-44
PF00157.16 Pou domain - N-terminal to homeobox domain 0.0076 12-43 / 13-49
PF01022.19 Bacterial regulatory protein, arsR family 0.0087 18-44 / 15-40

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein 1:XRE family transcriptional regulator 1:HTH-domain containing protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0003700 DNA binding transcription factor activity
GO:0000150 recombinase activity
GO:0006313 transposition, DNA-mediated
GO:0016987 sigma factor activity
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0043565 sequence-specific DNA binding
GO:0004803 transposase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0019069 viral capsid assembly
GO:0006352 DNA-templated transcription, initiation
GO:0051775 response to redox state
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated

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