phrog_14314 is made of 7 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
242 336 252


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p138016 no NCBI prot ID no annotation VI_04178 Actinobacteria_gi_494002731 Viruses.
JF704115_p87 AEK07836.1 HNH endonuclease domain protein JF704115 Mycobacterium virus Yoshi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
p355157 no NCBI prot ID no annotation VI_04171 Actinobacteria_gi_444434225 Viruses.
NC_026589_p76 YP_009124730.1 HNH domain protein NC_026589 Mycobacterium phage Sbash Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Chenonavirus.
MG845393_p61 AUV61626.1 HNH endonuclease MG845393 Gordonia phage Beenie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_028946_p73 YP_009212715.1 HNH endonuclease NC_028946 Mycobacterium phage Dante Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
KX620754_p61 AOT24650.1 HNH endonuclease domain protein KX620754 Propionibacterium phage G4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Doucettevirus; Propionibacterium virus G4.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3171 46 replication initiation protein DNA, RNA and nucleotide metabolism 4 5.58E-19 9.38
phrog_3926 36 replication initiation protein DNA, RNA and nucleotide metabolism 2 2.14E-11 1.79

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 97.8 4.2E-08 10-66 / 95-155
phrog_10378 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 8.1E-06 10-86 / 99-183
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 98.0 5.9E-09 5-64 / 20-82
phrog_12576 HNH endonuclease DNA, RNA and nucleotide metabolism 95.2 0.00096 14-67 / 26-92
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 3.1E-08 13-64 / 143-200
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 98.6 2.4E-11 5-64 / 51-113
phrog_15103 no annotation unknown function 95.2 0.0011 4-58 / 188-248
phrog_15463 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 9.8E-05 12-63 / 127-181
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 99.3 1.1E-15 6-65 / 70-131
phrog_16986 no annotation unknown function 99.7 3.6E-22 3-64 / 7-68
phrog_1985 HNH endonuclease DNA, RNA and nucleotide metabolism 93.8 0.0069 15-67 / 66-131
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 99.3 9.8E-16 1-67 / 1-77
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 99.6 8E-19 5-67 / 24-83
phrog_22283 no annotation unknown function 90.6 0.052 13-61 / 19-68
phrog_2323 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 6.2E-06 5-65 / 14-90
phrog_23285 HNH endonuclease DNA, RNA and nucleotide metabolism 91.8 0.029 15-64 / 47-124
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.4E-06 27-66 / 123-162
phrog_25420 HNH endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0057 10-59 / 38-102
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2.3E-05 28-59 / 33-64
phrog_26098 no annotation unknown function 96.1 0.00012 14-60 / 132-182
phrog_26663 no annotation unknown function 93.7 0.0075 8-62 / 26-79
phrog_29143 HNH endonuclease DNA, RNA and nucleotide metabolism 94.2 0.0043 12-82 / 15-89
phrog_2914 endonuclease VII DNA, RNA and nucleotide metabolism 94.4 0.0033 4-64 / 26-81
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 98.7 8.1E-12 7-64 / 19-73
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 98.6 3.5E-11 12-67 / 24-86
phrog_35175 HNH endonuclease DNA, RNA and nucleotide metabolism 92.9 0.014 9-61 / 37-113
phrog_4581 terminase small subunit head and packaging 97.2 1.2E-06 5-63 / 51-107
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 1.6E-13 4-67 / 11-74
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 99.2 3.1E-15 5-64 / 39-99
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2E-06 11-70 / 1-63
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 98.4 2.5E-10 15-66 / 4-56
phrog_655 homing endonuclease DNA, RNA and nucleotide metabolism 96.4 4.9E-05 27-52 / 19-44
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 97.6 1.9E-07 3-61 / 28-83
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00013 4-67 / 6-71
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 99.3 1.3E-15 11-64 / 63-112
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 97.0 4.9E-06 4-69 / 15-84
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 97.4 4.7E-07 6-60 / 119-183
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 98.8 3.3E-12 3-65 / 97-156
phrog_9443 HNH endonuclease DNA, RNA and nucleotide metabolism 93.4 0.0095 9-73 / 91-152
phrog_9508 HNH endonuclease DNA, RNA and nucleotide metabolism 92.9 0.015 14-67 / 18-77
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 2.6E-08 7-67 / 101-170
phrog_960 HNH endonuclease DNA, RNA and nucleotide metabolism 93.7 0.0077 18-60 / 41-83
phrog_9645 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.3E-05 13-87 / 21-98

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05315.10 ICEA Protein 4.4E-06 3-63 / 80-149
PF13391.5 HNH endonuclease 4E-06 19-67 / 1-48
PF13395.5 HNH endonuclease 5.8E-06 19-64 / 1-51
PF01844.22 HNH endonuclease 8.8E-06 19-63 / 1-47
PF05766.11 Bacteriophage Lambda NinG protein 2.7E-05 6-64 / 76-136
PF14279.5 HNH endonuclease 3.2E-05 19-64 / 1-45
PF06147.10 Protein of unknown function (DUF968) 0.0004 15-64 / 126-174
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.0062 16-65 / 253-297

Annotations of the NCBI proteins of this PHROG


2:HNH endonuclease 2:HNH endonuclease domain protein 1:HNH domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

Loading in process