phrog_15152 is made of 6 protein sequences and is annotated as "HTH DNA binding protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
81 84 83


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF140418_p88 ASR83672.1 HTH DNA binding domain protein MF140418 Arthrobacter phage LiSara Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; unclassified Laroyevirus.
MF140434_p87 ASR84185.1 HTH DNA binding domain protein MF140434 Arthrobacter phage Wheelbite Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; unclassified Laroyevirus.
MG099950_p88 ATW59965.1 HTH DNA binding domain protein MG099950 Arthrobacter phage Waltz Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; unclassified Laroyevirus.
KU160654_p91 ALY09616.1 HTH DNA binding domain protein KU160654 Arthrobacter phage Laroye Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; Arthrobacter virus Laroye.
MF140427_p90 ASR83969.1 HTH DNA binding domain protein MF140427 Arthrobacter phage Shrooms Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; unclassified Laroyevirus.
KU160664_p91 ALY10257.1 HTH DNA binding domain protein KU160664 Arthrobacter phage Salgado Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; unclassified Laroyevirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_15522 6 HNH endonuclease DNA, RNA and nucleotide metabolism 6 0 1000
phrog_16475 6 no annotation unknown function 6 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11376 no annotation unknown function 90.6 0.05 45-75 / 57-87
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 94.7 0.0022 44-73 / 17-46
phrog_1373 transcriptional regulator transcription regulation 94.8 0.0021 43-71 / 41-69
phrog_20467 HNH endonuclease DNA, RNA and nucleotide metabolism 94.6 0.0027 36-69 / 60-93
phrog_2328 transcriptional repressor transcription regulation 90.9 0.045 45-73 / 27-55
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.7 0.00033 43-75 / 17-53
phrog_36 transcriptional regulator transcription regulation 94.0 0.0054 24-67 / 83-126
phrog_3910 transcriptional regulator transcription regulation 94.1 0.005 42-72 / 75-105
phrog_4779 transcriptional regulator transcription regulation 95.9 0.00021 44-70 / 12-38
phrog_6156 endonuclease DNA, RNA and nucleotide metabolism 91.2 0.038 45-72 / 33-60
phrog_6223 transcriptional repressor transcription regulation 92.1 0.024 46-73 / 17-44
phrog_645 Rnase E DNA, RNA and nucleotide metabolism 93.0 0.014 35-68 / 24-57
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 95.4 0.00067 30-73 / 52-95
phrog_66 excisionase and transcriptional regulator integration and excision 91.2 0.038 47-69 / 10-32
phrog_6831 transcriptional regulator transcription regulation 92.5 0.02 44-71 / 13-40
phrog_686 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.2 0.0011 38-69 / 28-60
phrog_925 HTH DNA binding protein DNA, RNA and nucleotide metabolism 92.7 0.016 44-73 / 15-44

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF07638.10 ECF sigma factor 1.2E-07 30-78 / 132-180
PF03333.12 Adhesin biosynthesis transcription regulatory protein 2.4E-07 27-79 / 35-87
PF07374.10 Protein of unknown function (DUF1492) 2E-06 25-74 / 48-98
PF05331.10 Protein of unknown function (DUF742) 3.1E-06 30-74 / 37-80
PF06530.11 Phage antitermination protein Q 4.7E-06 33-78 / 65-110
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 6.8E-06 28-77 / 14-63
PF04545.15 Sigma-70, region 4 8.5E-06 33-75 / 6-52
PF16509.4 TrfB plasmid transcriptional repressor 8.9E-06 29-75 / 13-59
PF08281.11 Sigma-70, region 4 9.3E-06 31-72 / 10-51
PF05263.10 Protein of unknown function (DUF722) 1.1E-05 24-75 / 74-132
PF12759.6 InsA C-terminal domain 1.9E-05 44-70 / 18-44
PF07750.10 GcrA cell cycle regulator 1.7E-05 38-73 / 9-45
PF02001.15 Protein of unknown function DUF134 2.3E-05 29-78 / 29-78
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 3E-05 46-77 / 18-49
PF07141.10 Putative bacteriophage terminase small subunit 3.2E-05 43-74 / 27-58
PF16264.4 SatD family (SatD) 3.5E-05 26-77 / 145-201
PF08822.10 Protein of unknown function (DUF1804) 4.6E-05 37-72 / 8-44
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 5.4E-05 45-73 / 11-39
PF05344.10 Domain of Unknown Function (DUF746) 6.2E-05 45-75 / 10-40
PF00292.17 'Paired box' domain 7.2E-05 34-72 / 20-58
PF01710.15 Transposase 8.6E-05 44-72 / 15-43
PF10654.8 Protein of unknown function (DUF2481) 8.5E-05 45-75 / 78-108
PF04552.12 Sigma-54, DNA binding domain 0.00011 30-72 / 29-73
PF09607.9 Brinker DNA-binding domain 0.00014 48-73 / 26-51
PF06322.10 Phage NinH protein 0.00014 46-74 / 15-43
PF04218.12 CENP-B N-terminal DNA-binding domain 0.00016 48-75 / 24-51
PF05225.15 helix-turn-helix, Psq domain 0.00018 45-72 / 14-42
PF13936.5 Helix-turn-helix domain 0.00021 45-69 / 18-42
PF04936.11 Protein of unknown function (DUF658) 0.0002 47-72 / 14-39
PF02796.14 Helix-turn-helix domain of resolvase 0.00025 46-69 / 20-43
PF13011.5 leucine-zipper of insertion element IS481 0.00034 45-73 / 22-50
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.00034 46-71 / 26-50
PF08765.10 Mor transcription activator family 0.00043 46-75 / 71-100
PF01371.18 Trp repressor protein 0.00053 43-73 / 44-74
PF11427.7 Tc3 transposase 0.00057 46-72 / 19-45
PF04967.11 HTH DNA binding domain 0.00062 48-74 / 24-50
PF11242.7 Protein of unknown function (DUF2774) 0.00064 44-75 / 11-42
PF10668.8 Phage terminase small subunit 0.00069 47-73 / 22-48
PF02954.18 Bacterial regulatory protein, Fis family 0.00071 47-70 / 16-39
PF10975.7 Protein of unknown function (DUF2802) 0.00081 38-68 / 34-64
PF14493.5 Helix-turn-helix domain 0.00098 46-72 / 11-37
PF13412.5 Winged helix-turn-helix DNA-binding 0.0011 47-73 / 17-43
PF08535.9 KorB domain 0.0011 47-71 / 3-27
PF13411.5 MerR HTH family regulatory protein 0.0012 49-71 / 2-24
PF17443.1 Uncharacterized protein pXO2-72 0.0011 47-68 / 8-29
PF13556.5 PucR C-terminal helix-turn-helix domain 0.0013 47-74 / 12-39
PF01381.21 Helix-turn-helix 0.0014 46-70 / 8-32
PF13518.5 Helix-turn-helix domain 0.0015 46-73 / 10-37
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.0014 47-71 / 107-131
PF13384.5 Homeodomain-like domain 0.0016 47-71 / 17-41
PF07453.12 NUMOD1 domain 0.0019 48-67 / 20-39
PF06627.10 Protein of unknown function (DUF1153) 0.002 46-74 / 45-73
PF13309.5 HTH domain 0.002 48-68 / 42-62
PF00376.22 MerR family regulatory protein 0.0022 51-71 / 3-23
PF00356.20 Bacterial regulatory proteins, lacI family 0.0022 50-70 / 2-22
PF13404.5 AsnC-type helix-turn-helix domain 0.0022 47-70 / 17-40
PF13591.5 MerR HTH family regulatory protein 0.0022 49-70 / 2-23
PF09862.8 Protein of unknown function (DUF2089) 0.0024 35-75 / 37-77
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.0027 48-69 / 4-25
PF06806.11 Putative excisionase (DUF1233) 0.0027 48-69 / 10-31
PF13413.5 Helix-turn-helix domain 0.0034 46-71 / 8-33
PF01527.19 Transposase 0.0037 45-72 / 19-46
PF07278.10 Protein of unknown function (DUF1441) 0.0035 48-71 / 2-25
PF00196.18 Bacterial regulatory proteins, luxR family 0.0039 46-76 / 16-46
PF13551.5 Winged helix-turn helix 0.0041 47-73 / 11-37
PF16677.4 DNA-packaging protein gp3 0.0043 46-71 / 28-53
PF01418.16 Helix-turn-helix domain, rpiR family 0.0051 47-71 / 34-58
PF02042.14 RWP-RK domain 0.0058 46-71 / 11-36
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0055 46-72 / 22-48
PF12802.6 MarR family 0.006 48-73 / 22-47
PF09035.9 Excisionase from transposon Tn916 0.006 47-68 / 15-36
PF07037.10 Putative transcription regulator (DUF1323) 0.0061 49-70 / 2-23
PF12116.7 Stage III sporulation protein D 0.0065 46-71 / 18-43
PF00325.19 Bacterial regulatory proteins, crp family 0.007 50-69 / 5-24
PF15978.4 Tn7-like transposition protein D 0.0069 46-72 / 202-228
PF08280.10 M protein trans-acting positive regulator (MGA) HTH domain 0.0073 47-76 / 20-49
PF10743.8 Regulatory phage protein cox 0.0075 47-71 / 11-35
PF12728.6 Helix-turn-helix domain 0.0083 49-69 / 3-24
PF08222.10 CodY helix-turn-helix domain 0.0084 48-72 / 5-29
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 0.0083 45-71 / 21-47

Annotations of the NCBI proteins of this PHROG


6:HTH DNA binding domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0043565 sequence-specific DNA binding
GO:0004803 transposase activity
GO:0005524 ATP binding
GO:0000150 recombinase activity
GO:0006313 transposition, DNA-mediated
GO:0003700 DNA binding transcription factor activity
GO:0005667 transcription factor complex
GO:0019069 viral capsid assembly
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0016987 sigma factor activity
GO:0006355 regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0006352 DNA-templated transcription, initiation

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