phrog_15463 is made of 6 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
431.5 552 472


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_031099_p63 YP_009289872.1 HNH endonuclease domain protein NC_031099 Gordonia phage Hedwig Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Hedwigvirus; Gordonia virus Hedwig.
NC_030930_p61 YP_009275628.1 HNH endonuclease NC_030930 Gordonia phage Bowser Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bowservirus; Gordonia virus Bowser.
NC_031255_p65 YP_009303448.1 HNH endonuclease NC_031255 Gordonia phage Schwabeltier Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Schnabeltiervirus; Gordonia virus Schnabeltier.
MG941013_p51 AVJ50988.1 HNH endonuclease domain protein MG941013 Actinomyces phage xhp1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_031004_p54 YP_009277972.1 HNH endonuclease domain protein NC_031004 Gordonia phage Nyceirae Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nyceiraevirus; Gordonia virus Nyceirae.
p385434 no NCBI prot ID no annotation VI_04150 Actinobacteria_gi_498792577 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_35289 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 97.0 3.7E-06 128-193 / 98-164
phrog_12576 HNH endonuclease DNA, RNA and nucleotide metabolism 90.7 0.049 126-198 / 23-109
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 1.1E-05 128-183 / 143-201
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00012 127-181 / 12-63
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.0004 124-183 / 55-114
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 98.6 3.4E-11 119-194 / 68-142
phrog_16986 no annotation unknown function 94.4 0.0036 125-182 / 14-68
phrog_1882 no annotation unknown function 96.3 6.5E-05 1-97 / 1-79
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 6.6E-07 122-188 / 7-80
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 3.4E-08 130-196 / 34-93
phrog_2447 replication initiation protein DNA, RNA and nucleotide metabolism 99.0 3.6E-13 1-116 / 1-116
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 95.3 0.00085 151-184 / 35-71
phrog_26098 no annotation unknown function 100.0 9.3E-62 1-225 / 1-239
phrog_30000 no annotation unknown function 98.4 2.4E-10 1-95 / 1-88
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 91.7 0.03 122-186 / 19-77
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 97.0 3.1E-06 127-187 / 24-88
phrog_3926 replication initiation protein DNA, RNA and nucleotide metabolism 98.7 8.1E-12 1-114 / 4-100
phrog_4581 terminase small subunit head and packaging 92.6 0.018 121-183 / 52-109
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 97.4 5E-07 119-184 / 11-73
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 95.9 0.00022 121-187 / 40-104
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0022 130-184 / 4-56
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 90.5 0.052 118-177 / 28-81
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 95.9 0.0002 122-182 / 59-112
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 97.9 2.4E-08 126-188 / 105-161
phrog_9443 HNH endonuclease DNA, RNA and nucleotide metabolism 92.7 0.017 132-185 / 99-148
phrog_9474 replication initiation protein DNA, RNA and nucleotide metabolism 94.9 0.0017 1-131 / 1-129
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 5E-05 125-200 / 104-188
phrog_9645 HNH endonuclease DNA, RNA and nucleotide metabolism 95.3 0.00086 114-194 / 7-88

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF09681.9 N-terminal phage replisome organiser (Phage_rep_org_N) 4.7E-09 32-134 / 1-104
PF14297.5 Domain of unknown function (DUF4373) 1.2E-05 32-112 / 1-81
PF13395.5 HNH endonuclease 2.1E-05 164-212 / 1-51
PF05315.10 ICEA Protein 4E-05 148-212 / 80-150
PF14279.5 HNH endonuclease 0.00012 164-213 / 1-46
PF01844.22 HNH endonuclease 0.00022 164-210 / 1-46
PF05766.11 Bacteriophage Lambda NinG protein 0.00024 151-212 / 76-136
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.00031 161-215 / 253-299
PF13391.5 HNH endonuclease 0.0026 164-211 / 1-44

Annotations of the NCBI proteins of this PHROG


3:HNH endonuclease domain protein 2:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

Loading in process