phrog_15522 is made of 6 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
108.33 109 108


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF140418_p87 ASR83671.1 HNH endonuclease MF140418 Arthrobacter phage LiSara Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; unclassified Laroyevirus.
KU160654_p90 ALY09615.1 HNH endonuclease domain protein KU160654 Arthrobacter phage Laroye Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; Arthrobacter virus Laroye.
KU160664_p90 ALY10256.1 HNH endonuclease domain protein KU160664 Arthrobacter phage Salgado Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; unclassified Laroyevirus.
MF140434_p86 ASR84184.1 HNH endonuclease MF140434 Arthrobacter phage Wheelbite Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; unclassified Laroyevirus.
MG099950_p87 ATW59964.1 HNH endonuclease MG099950 Arthrobacter phage Waltz Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; unclassified Laroyevirus.
MF140427_p89 ASR83968.1 HNH endonuclease MF140427 Arthrobacter phage Shrooms Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Laroyevirus; unclassified Laroyevirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_15900 6 no annotation unknown function 6 0 1000
phrog_15152 6 HTH DNA binding protein DNA, RNA and nucleotide metabolism 6 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 92.8 0.015 22-79 / 57-112
phrog_14515 HNH endonuclease DNA, RNA and nucleotide metabolism 95.0 0.0014 62-91 / 8-41
phrog_15103 no annotation unknown function 95.8 0.00026 27-90 / 200-264
phrog_31911 no annotation unknown function 91.0 0.042 47-85 / 36-72
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 93.3 0.011 18-75 / 19-68
phrog_4581 terminase small subunit head and packaging 92.2 0.023 25-78 / 60-106
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 4.6E-05 14-78 / 37-97
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 94.9 0.0017 26-84 / 40-90
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 98.4 4.1E-10 4-91 / 5-80
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 94.4 0.0035 26-75 / 128-182

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05766.11 Bacteriophage Lambda NinG protein 6E-12 13-103 / 72-157
PF05315.10 ICEA Protein 2E-10 11-80 / 77-150
PF13395.5 HNH endonuclease 8.4E-10 30-80 / 1-51
PF01844.22 HNH endonuclease 2E-09 30-79 / 1-47
PF14279.5 HNH endonuclease 4E-09 30-81 / 1-46
PF13391.5 HNH endonuclease 3.3E-08 30-81 / 1-46
PF06147.10 Protein of unknown function (DUF968) 1.7E-07 26-80 / 126-174
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 2.5E-07 27-81 / 253-297
PF16784.4 Putative HNHc nuclease 4.3E-06 26-81 / 122-172

Annotations of the NCBI proteins of this PHROG


4:HNH endonuclease 2:HNH endonuclease domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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