phrog_16278 is made of 6 protein sequences and is annotated as "HTH DNA binding protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
164 182 170


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY624611_p10 ARM68638.1 hypothetical protein KY624611 Corynebacterium phage LGCM-V4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p204516 no NCBI prot ID no annotation VI_04114 Actinobacteria_gi_419859811 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF197383_p35 ASJ78994.1 helix-turn-helix DNA binding protein MF197383 Corynebacterium phage Poushou Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Poushouvirus; Corynebacterium virus Poushou.
p210170 no NCBI prot ID no annotation VI_04108 Actinobacteria_gi_484048417 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_030939_p32 YP_009276387.1 hypothetical protein NC_030939 Gordonia phage GMA4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p342462 no NCBI prot ID no annotation VI_04148 Actinobacteria_gi_498789783 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_87 993 metallo-protease other 5 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1033 ParB-like partition protein DNA, RNA and nucleotide metabolism 90.6 0.051 17-62 / 144-201
phrog_13326 no annotation unknown function 91.9 0.027 9-62 / 12-66
phrog_1373 transcriptional regulator transcription regulation 95.3 0.00087 16-57 / 46-88
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 95.4 0.00065 16-57 / 25-67
phrog_1746 transcriptional repressor transcription regulation 95.4 0.00069 17-74 / 25-83
phrog_18815 no annotation unknown function 99.1 1.7E-14 2-116 / 1-114
phrog_19097 transcriptional repressor transcription regulation 97.4 5E-07 2-98 / 5-103
phrog_19579 transcriptional regulator transcription regulation 98.0 7.8E-09 8-104 / 9-120
phrog_2136 no annotation unknown function 91.8 0.029 4-53 / 29-82
phrog_2838 transcriptional repressor transcription regulation 90.5 0.053 31-98 / 72-143
phrog_34939 no annotation unknown function 96.4 4.2E-05 15-56 / 23-66
phrog_35 transcriptional repressor transcription regulation 93.0 0.013 1-52 / 2-52
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.7 0.03 9-63 / 15-70
phrog_3949 transcriptional repressor transcription regulation 98.1 3.1E-09 2-98 / 14-113
phrog_3 transcriptional repressor transcription regulation 95.4 0.0007 16-57 / 18-60
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.5 2.8E-05 5-61 / 9-66
phrog_4583 transcriptional repressor transcription regulation 95.8 0.0003 15-62 / 24-72
phrog_4 transcriptional repressor transcription regulation 92.2 0.022 2-60 / 2-59
phrog_5301 transcriptional repressor transcription regulation 98.1 5.2E-09 4-99 / 6-114
phrog_638 transcriptional regulator transcription regulation 95.3 0.00091 2-98 / 1-89
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 90.3 0.057 6-49 / 60-103
phrog_7241 transcriptional regulator transcription regulation 95.9 0.0002 17-56 / 77-117
phrog_725 CII-like regulator transcription regulation 92.5 0.019 15-74 / 28-83
phrog_8 transcriptional regulator transcription regulation 94.9 0.0018 18-57 / 17-56
phrog_9103 transcriptional repressor transcription regulation 93.2 0.012 8-63 / 14-70
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 92.4 0.02 3-41 / 7-45

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 3.9E-07 6-67 / 7-77
PF14590.5 Domain of unknown function (DUF4447) 1.9E-06 7-68 / 5-72
PF05339.10 Protein of unknown function (DUF739) 2.2E-06 12-65 / 6-62
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 2.3E-06 20-68 / 11-60
PF13744.5 Helix-turn-helix domain 2.6E-06 9-66 / 18-79
PF01381.21 Helix-turn-helix 3.5E-06 20-64 / 9-54
PF13443.5 Cro/C1-type HTH DNA-binding domain 7.3E-06 20-67 / 10-61
PF13413.5 Helix-turn-helix domain 7.9E-06 20-63 / 9-59
PF05269.10 Bacteriophage CII protein 8.5E-06 7-67 / 6-69
PF12844.6 Helix-turn-helix domain 8.5E-06 20-67 / 12-60
PF08667.9 BetR domain 1.3E-05 7-69 / 3-72
PF04645.11 Protein of unknown function, DUF603 1.3E-05 5-65 / 3-66
PF13560.5 Helix-turn-helix domain 3.4E-05 11-64 / 3-62
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 3.7E-05 10-66 / 70-128
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 4.6E-05 21-68 / 9-57
PF14549.5 DNA-binding transcriptional regulator Cro 0.00014 20-64 / 10-51
PF13693.5 Winged helix-turn-helix DNA-binding 0.00016 20-67 / 15-60
PF12116.7 Stage III sporulation protein D 0.00032 20-62 / 19-63
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.00046 11-59 / 115-166
PF00356.20 Bacterial regulatory proteins, lacI family 0.00055 22-55 / 1-35
PF02376.14 CUT domain 0.00084 7-66 / 5-66
PF10654.8 Protein of unknown function (DUF2481) 0.0013 20-43 / 80-103
PF08535.9 KorB domain 0.0068 20-43 / 3-26

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein 1:helix-turn-helix DNA binding protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0043565 sequence-specific DNA binding
GO:0003677 DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0005634 nucleus

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