phrog_16427 is made of 6 protein sequences and is annotated as "DNA methyltransferase"
Functional category: other


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
151.17 263 127


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p321022 no NCBI prot ID no annotation VI_05083 Bacilli_gi_481025831 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p421493 no NCBI prot ID no annotation VI_05082 Bacilli_gi_481025765 Viruses.
KY065492_p18 APD23862.1 DNA methylase KY065492 Streptococcus phage IPP54 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p150251 no NCBI prot ID no annotation VI_00779 Bacilli_gi_169832377_58228_99038 Viruses.
MG711466_p15 AUV56728.1 DNA-cytosine methyltransferase MG711466 Faecalibacterium phage FP_Toutatis Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Toutatisvirus; Faecalibacterium virus Toutatis.
p59571 no NCBI prot ID no annotation VI_00410 Bacilli_gi_423399425 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_363 344 DNA methyltransferase other 6 8.86E-22 12.17
phrog_3859 37 no annotation unknown function 2 1.41E-11 1.97
phrog_3947 36 no annotation unknown function 2 1.29E-11 2.01

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_116 DNA methyltransferase other 99.5 3.5E-18 45-125 / 213-297
phrog_13621 no annotation unknown function 98.5 7E-11 74-124 / 1-54
phrog_16528 DNA methyltransferase other 99.7 6.5E-21 69-123 / 73-123
phrog_17284 no annotation unknown function 100.0 1.8E-34 68-125 / 15-72
phrog_23072 DNA methyltransferase other 95.1 0.0012 68-122 / 317-374
phrog_23296 DNA methyltransferase other 96.3 7.2E-05 84-124 / 11-55
phrog_23910 no annotation unknown function 93.4 0.0097 72-123 / 42-94
phrog_26324 DNA methyltransferase other 99.9 4.2E-27 56-124 / 131-204
phrog_31585 no annotation unknown function 94.1 0.0049 68-124 / 8-62
phrog_38038 no annotation unknown function 98.8 1.8E-12 2-124 / 167-347
phrog_8411 no annotation unknown function 100.0 1.7E-54 1-110 / 94-206

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00145.16 C-5 cytosine-specific DNA methylase 0.0007 178-220 / 2-42
PF07757.12 Predicted AdoMet-dependent methyltransferase 5.4E-06 175-226 / 59-107
PF05958.10 tRNA (Uracil-5-)-methyltransferase 1.7E-05 176-231 / 201-258
PF06325.12 Ribosomal protein L11 methyltransferase (PrmA) 7.6E-05 174-221 / 171-216
PF00398.19 Ribosomal RNA adenine dimethylase 0.0001 175-230 / 30-85
PF07091.10 Ribosomal RNA methyltransferase (FmrO) 0.00037 174-221 / 101-147
PF07021.11 Methionine biosynthesis protein MetW 0.00058 174-219 / 12-54
PF04378.12 Ribosomal RNA large subunit methyltransferase D, RlmJ 0.00061 175-221 / 60-103
PF05175.13 Methyltransferase small domain 0.00064 175-221 / 31-76
PF13489.5 Methyltransferase domain 0.00066 175-221 / 21-65
PF02636.16 Putative S-adenosyl-L-methionine-dependent methyltransferase 0.00071 176-221 / 18-69
PF05185.15 PRMT5 arginine-N-methyltransferase 0.00076 175-220 / 59-108
PF12847.6 Methyltransferase domain 0.00078 175-221 / 14-59
PF02475.15 Met-10+ like-protein 0.00093 174-221 / 99-145
PF10672.8 S-adenosylmethionine-dependent methyltransferase 0.001 175-221 / 123-167
PF03291.15 mRNA capping enzyme 0.001 175-221 / 59-103
PF01170.17 Putative RNA methylase family UPF0020 0.0011 175-221 / 28-112
PF03686.12 Uncharacterised protein family (UPF0146) 0.0011 175-211 / 14-49
PF01739.17 CheR methyltransferase, SAM binding domain 0.0011 175-221 / 33-85
PF13679.5 Methyltransferase domain 0.0012 175-221 / 25-76
PF05724.10 Thiopurine S-methyltransferase (TPMT) 0.0012 175-219 / 38-79
PF11599.7 RRNA methyltransferase AviRa 0.0013 175-221 / 49-96
PF02390.16 Putative methyltransferase 0.0012 176-220 / 2-45
PF01795.18 MraW methylase family 0.0013 175-220 / 20-65
PF07942.11 N2227-like protein 0.0014 175-221 / 57-100
PF04445.12 Putative SAM-dependent methyltransferase 0.0015 175-221 / 64-107
PF03602.14 Conserved hypothetical protein 95 0.0015 174-221 / 36-81
PF09243.9 Mitochondrial small ribosomal subunit Rsm22 0.0016 175-221 / 34-80
PF05206.13 Methyltransferase TRM13 0.0017 175-220 / 17-71
PF08123.12 Histone methylation protein DOT1 0.0018 175-220 / 42-86
PF05575.10 Vibrio cholerae RfbT protein 0.0021 174-221 / 78-124
PF10017.8 Histidine-specific methyltransferase, SAM-dependent 0.0021 175-221 / 62-107
PF01234.16 NNMT/PNMT/TEMT family 0.0021 175-221 / 56-100
PF12692.6 S-adenosyl-L-methionine methyltransferase 0.0021 175-218 / 28-70
PF05891.11 AdoMet dependent proline di-methyltransferase 0.0021 175-220 / 55-98
PF03848.13 Tellurite resistance protein TehB 0.0021 175-221 / 30-73
PF06080.11 Protein of unknown function (DUF938) 0.0022 175-220 / 27-71
PF10294.8 Lysine methyltransferase 0.0025 175-221 / 45-89
PF09445.9 RNA cap guanine-N2 methyltransferase 0.0026 177-220 / 2-42
PF05401.10 Nodulation protein S (NodS) 0.0026 175-220 / 43-85
PF12147.7 Putative methyltransferase 0.0027 175-221 / 131-178
PF02527.14 rRNA small subunit methyltransferase G 0.0027 178-221 / 54-96
PF01135.18 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 0.0027 175-221 / 71-117
PF01564.16 Spermine/spermidine synthase domain 0.0027 175-221 / 18-63
PF01555.17 DNA methylase 0.0028 175-217 / 143-182
PF03059.15 Nicotianamine synthase protein 0.0028 175-221 / 121-168
PF03269.13 Caenorhabditis protein of unknown function, DUF268 0.0029 177-217 / 2-40
PF03141.15 Putative S-adenosyl-L-methionine-dependent methyltransferase 0.003 175-219 / 113-157
PF08242.11 Methyltransferase domain 0.0029 180-221 / 1-43
PF01269.16 Fibrillarin 0.0031 175-220 / 72-117
PF04816.11 tRNA (adenine(22)-N(1))-methyltransferase 0.0033 179-221 / 1-42
PF08003.10 Protein of unknown function (DUF1698) 0.0034 175-220 / 116-159
PF05971.11 Protein of unknown function (DUF890) 0.0036 175-221 / 103-148
PF13847.5 Methyltransferase domain 0.0038 175-220 / 3-48
PF02353.19 Mycolic acid cyclopropane synthetase 0.0041 175-220 / 61-104
PF05219.11 DREV methyltransferase 0.0044 175-218 / 90-130
PF01209.17 ubiE/COQ5 methyltransferase family 0.0046 178-220 / 59-106
PF02005.15 N2,N2-dimethylguanosine tRNA methyltransferase 0.0053 175-221 / 100-146
PF02384.15 N-6 DNA Methylase 0.0059 175-220 / 45-92
PF01189.16 16S rRNA methyltransferase RsmB/F 0.0058 175-221 / 8-54
PF08704.9 tRNA methyltransferase complex GCD14 subunit 0.0061 175-221 / 40-86
PF03492.14 SAM dependent carboxyl methyltransferase 0.0065 175-220 / 13-72
PF11968.7 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 0.0066 175-220 / 52-95
PF01596.16 O-methyltransferase 0.0071 175-220 / 48-93

Annotations of the NCBI proteins of this PHROG


1:DNA-cytosine methyltransferase 1:DNA methylase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K00558 DNMT1, dcm : DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] ko00270 Cysteine and methionine metabolism
ko05206 MicroRNAs in cancer 		529 6

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0009877 nodulation
GO:0008173 RNA methyltransferase activity
GO:0004809 tRNA (guanine-N2-)-methyltransferase activity
GO:0018024 histone-lysine N-methyltransferase activity
GO:0030488 tRNA methylation
GO:0031515 tRNA (m1A) methyltransferase complex
GO:0070475 rRNA base methylation
GO:0009312 oligosaccharide biosynthetic process
GO:0003677 DNA binding
GO:0008649 rRNA methyltransferase activity
GO:0001510 RNA methylation
GO:0016429 tRNA (adenine-N1-)-methyltransferase activity
GO:0030418 nicotianamine biosynthetic process
GO:0031167 rRNA methylation
GO:0006480 N-terminal protein amino acid methylation
GO:0008170 N-methyltransferase activity
GO:0006306 DNA methylation
GO:0003723 RNA binding
GO:0006396 RNA processing
GO:0006412 translation
GO:0008171 O-methyltransferase activity
GO:0008168 methyltransferase activity
GO:0005737 cytoplasm
GO:0009452 7-methylguanosine RNA capping
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0006364 rRNA processing
GO:0008990 rRNA (guanine-N2-)-methyltransferase activity
GO:0030410 nicotianamine synthase activity
GO:0008033 tRNA processing

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