phrog_16726 is made of 5 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
204.4 359 181


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_019516_p148 YP_007006139.1 HNH endonuclease NC_019516 Cyanophage S-TIM5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Aurunvirus; Synechococcus virus STIM5.
NC_015569_p205 YP_004508638.1 HNH endonuclease NC_015569 Synechococcus phage S-CRM01 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
MF403008_p252 ASV44726.1 HNH endonuclease family protein MF403008 Agrobacterium phage Atu_ph07 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Polybotosvirus; Agrobacterium virus Atuph07.
KY624611_p20 ARM68648.1 hypothetical protein KY624611 Corynebacterium phage LGCM-V4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_009760_p173 YP_001429763.1 mobile nuclease NC_009760 Bacillus phage 0305phi8-36 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
no colocalized PHROGS                                                                                          

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 98.0 8.1E-09 74-135 / 95-158
phrog_10378 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0019 74-130 / 99-153
phrog_11604 HNH endonuclease DNA, RNA and nucleotide metabolism 92.3 0.021 70-136 / 65-137
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 97.7 8.9E-08 70-130 / 21-82
phrog_12400 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 9.5E-06 68-158 / 17-111
phrog_12576 HNH endonuclease DNA, RNA and nucleotide metabolism 95.4 0.00071 69-136 / 17-95
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 98.2 2.3E-09 71-133 / 138-203
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 99.2 3.2E-15 69-131 / 5-65
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 98.3 6.6E-10 69-132 / 51-115
phrog_15103 no annotation unknown function 94.1 0.0052 64-126 / 184-250
phrog_15463 HNH endonuclease DNA, RNA and nucleotide metabolism 98.5 8E-11 68-142 / 119-194
phrog_16016 HNH endonuclease DNA, RNA and nucleotide metabolism 92.0 0.026 68-129 / 36-99
phrog_16204 no annotation unknown function 92.3 0.022 68-131 / 21-84
phrog_16986 no annotation unknown function 99.0 2.8E-13 69-136 / 9-74
phrog_17283 HNH endonuclease DNA, RNA and nucleotide metabolism 93.9 0.0061 97-131 / 9-44
phrog_18937 no annotation unknown function 94.8 0.002 79-136 / 95-156
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 2.5E-13 69-138 / 5-82
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 99.6 2.1E-19 67-134 / 22-84
phrog_22283 no annotation unknown function 93.6 0.0081 76-135 / 18-76
phrog_2323 HNH endonuclease DNA, RNA and nucleotide metabolism 92.1 0.024 74-133 / 18-92
phrog_23285 HNH endonuclease DNA, RNA and nucleotide metabolism 95.2 0.001 95-132 / 89-126
phrog_24030 RNA ligase DNA, RNA and nucleotide metabolism 93.1 0.012 64-127 / 2-62
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 97.5 3E-07 70-135 / 80-165
phrog_25420 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 7.9E-06 73-138 / 37-115
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2.1E-05 80-133 / 10-72
phrog_26098 no annotation unknown function 98.7 8.7E-12 50-150 / 94-206
phrog_29143 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 8.3E-05 76-131 / 15-75
phrog_2914 endonuclease VII DNA, RNA and nucleotide metabolism 94.3 0.0041 71-134 / 29-85
phrog_30443 HNH endonuclease DNA, RNA and nucleotide metabolism 91.3 0.037 64-126 / 42-102
phrog_32453 HNH endonuclease DNA, RNA and nucleotide metabolism 93.1 0.012 68-128 / 60-115
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 97.4 5.2E-07 71-133 / 19-76
phrog_33554 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 7.6E-06 71-141 / 10-91
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 98.6 2.7E-11 76-134 / 24-87
phrog_4234 HNH endonuclease DNA, RNA and nucleotide metabolism 90.2 0.058 80-105 / 27-47
phrog_4581 terminase small subunit head and packaging 97.6 1.3E-07 70-142 / 52-126
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 99.1 5.5E-14 68-139 / 11-80
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 98.7 6.4E-12 69-132 / 39-101
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 4.3E-05 75-133 / 1-60
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 98.3 9.4E-10 78-130 / 3-54
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2.6E-05 70-126 / 31-82
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 5.4E-05 68-133 / 6-72
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 98.2 1.3E-09 71-130 / 59-112
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 97.7 7.2E-08 72-124 / 121-181
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 99.3 1.7E-15 68-135 / 98-160
phrog_9508 HNH endonuclease DNA, RNA and nucleotide metabolism 95.0 0.0014 80-135 / 20-79
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 98.3 8.9E-10 71-131 / 101-168
phrog_960 HNH endonuclease DNA, RNA and nucleotide metabolism 95.1 0.0013 78-134 / 35-91
phrog_9645 HNH endonuclease DNA, RNA and nucleotide metabolism 97.9 1.9E-08 72-136 / 16-81

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13395.5 HNH endonuclease 2.8E-06 113-160 / 1-51
PF05766.11 Bacteriophage Lambda NinG protein 4.4E-06 94-160 / 70-136
PF01844.22 HNH endonuclease 7.3E-06 113-159 / 1-47
PF05315.10 ICEA Protein 9.5E-06 97-159 / 80-149
PF14279.5 HNH endonuclease 1.1E-05 113-161 / 1-46
PF13391.5 HNH endonuclease 0.00015 113-159 / 1-44
PF06147.10 Protein of unknown function (DUF968) 0.00027 108-159 / 125-173
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.00051 110-162 / 253-298

Annotations of the NCBI proteins of this PHROG


2:HNH endonuclease 1:HNH endonuclease family protein 1:mobile nuclease 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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