phrog_17821 is made of 5 protein sequences and is annotated as "HTH DNA binding protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
134.8 136 136


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KX688103_p30 AOZ65130.1 hypothetical protein KX688103 Arthrobacter phage Greenhouse Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Korravirus; unclassified Korravirus.
MF140424_p30 ASR83763.1 hypothetical protein MF140424 Arthrobacter phage Nubia Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Korravirus; unclassified Korravirus.
KU160652_p30 ALY09433.1 hypothetical protein KU160652 Arthrobacter phage Joann Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Korravirus; Arthrobacter virus Joann.
KX576640_p30 AOQ28242.1 helix-turn-helix DNA binding domain protein KX576640 Arthrobacter phage RcigaStruga Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Korravirus; unclassified Korravirus.
KX688102_p30 AOZ65069.1 hypothetical protein KX688102 Arthrobacter phage Oxynfrius Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Korravirus; unclassified Korravirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_62 1174 DNA helicase DNA, RNA and nucleotide metabolism 5 1.02E-15 6.11
phrog_5477 24 no annotation unknown function 5 3.83E-26 16.54

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1157 transposase integration and excision 95.8 0.00031 4-42 / 2-40
phrog_125 DNA invertase DNA, RNA and nucleotide metabolism 94.6 0.0026 9-43 / 148-182
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 95.1 0.0012 17-55 / 21-59
phrog_14131 DNA binding protein DNA, RNA and nucleotide metabolism 90.0 0.065 9-42 / 6-41
phrog_1456 DNA binding protein DNA, RNA and nucleotide metabolism 91.0 0.043 19-41 / 12-34
phrog_151 transposase integration and excision 91.6 0.032 5-39 / 9-43
phrog_1529 no annotation unknown function 94.3 0.0037 9-40 / 5-36
phrog_16311 no annotation unknown function 92.0 0.025 5-36 / 6-37
phrog_2308 no annotation unknown function 95.2 0.00095 5-86 / 2-67
phrog_24325 transcriptional regulator transcription regulation 91.3 0.037 18-55 / 64-91
phrog_2538 terminase small subunit head and packaging 91.6 0.032 5-42 / 5-42
phrog_268 no annotation unknown function 92.6 0.018 9-43 / 5-40
phrog_309 terminase small subunit head and packaging 95.5 0.00054 8-48 / 13-53
phrog_3855 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.8 0.00032 6-42 / 66-102
phrog_3 transcriptional repressor transcription regulation 94.2 0.0042 17-42 / 14-39
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 91.1 0.04 10-41 / 11-42
phrog_4494 no annotation unknown function 91.6 0.031 5-41 / 3-39
phrog_4646 transposase integration and excision 94.4 0.0033 2-38 / 5-41
phrog_5536 no annotation unknown function 94.9 0.0018 4-114 / 6-111
phrog_597 DNA binding protein DNA, RNA and nucleotide metabolism 92.1 0.024 14-59 / 9-62
phrog_638 transcriptional regulator transcription regulation 90.0 0.065 20-63 / 17-60
phrog_6555 no annotation unknown function 99.3 8.8E-16 67-135 / 5-72
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 95.2 0.00098 5-61 / 5-67
phrog_66 excisionase and transcriptional regulator integration and excision 92.7 0.017 16-42 / 6-32
phrog_6831 transcriptional regulator transcription regulation 93.9 0.0061 9-52 / 5-52
phrog_803 host nuclease inhibitor moron, auxiliary metabolic gene and host takeover 92.6 0.018 21-40 / 20-39
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 95.6 0.00045 15-89 / 57-144
phrog_8 transcriptional regulator transcription regulation 95.2 0.00097 17-53 / 12-48
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 92.1 0.025 20-47 / 19-45

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF12759.6 InsA C-terminal domain 6.8E-05 4-43 / 6-45
PF07750.10 GcrA cell cycle regulator 0.00011 3-43 / 2-43
PF00292.17 'Paired box' domain 0.00015 3-44 / 17-58
PF01710.15 Transposase 0.00016 3-44 / 2-43
PF09607.9 Brinker DNA-binding domain 0.00017 3-44 / 5-50
PF07141.10 Putative bacteriophage terminase small subunit 0.00019 9-46 / 21-58
PF08822.10 Protein of unknown function (DUF1804) 0.00021 3-44 / 2-44
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.00036 11-44 / 5-38
PF02796.14 Helix-turn-helix domain of resolvase 0.00045 6-42 / 8-44
PF13936.5 Helix-turn-helix domain 0.00045 4-42 / 5-43
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.00055 5-43 / 13-50
PF13011.5 leucine-zipper of insertion element IS481 0.00065 4-46 / 8-51
PF07638.10 ECF sigma factor 0.00068 4-43 / 134-173
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.00072 4-43 / 40-79
PF10668.8 Phage terminase small subunit 0.00078 3-44 / 4-47
PF05331.10 Protein of unknown function (DUF742) 0.00089 3-43 / 38-77
PF05344.10 Domain of Unknown Function (DUF746) 0.00098 14-44 / 7-37
PF04218.12 CENP-B N-terminal DNA-binding domain 0.001 5-43 / 8-47
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 0.0011 4-43 / 3-43
PF11427.7 Tc3 transposase 0.0014 4-43 / 5-44
PF04552.12 Sigma-54, DNA binding domain 0.0019 4-44 / 31-73
PF06627.10 Protein of unknown function (DUF1153) 0.002 5-46 / 31-73
PF08281.11 Sigma-70, region 4 0.0021 4-43 / 11-50
PF04545.15 Sigma-70, region 4 0.0023 3-43 / 4-48
PF06322.10 Phage NinH protein 0.0024 17-43 / 14-40
PF16677.4 DNA-packaging protein gp3 0.0026 4-46 / 6-56
PF13384.5 Homeodomain-like domain 0.0027 7-43 / 5-41
PF10654.8 Protein of unknown function (DUF2481) 0.0032 12-43 / 73-104
PF16509.4 TrfB plasmid transcriptional repressor 0.003 4-43 / 16-55
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.0033 3-43 / 88-131
PF04936.11 Protein of unknown function (DUF658) 0.0034 19-43 / 14-38
PF01527.19 Transposase 0.0034 4-44 / 5-46
PF07374.10 Protein of unknown function (DUF1492) 0.0035 6-43 / 58-95
PF13309.5 HTH domain 0.0037 20-41 / 42-63
PF01371.18 Trp repressor protein 0.0039 15-44 / 44-73
PF13518.5 Helix-turn-helix domain 0.0038 12-45 / 5-37
PF08765.10 Mor transcription activator family 0.0042 12-44 / 66-97
PF14493.5 Helix-turn-helix domain 0.0042 12-45 / 5-38
PF13412.5 Winged helix-turn-helix DNA-binding 0.0049 18-43 / 16-41
PF06530.11 Phage antitermination protein Q 0.0065 5-43 / 65-103
PF05225.15 helix-turn-helix, Psq domain 0.0069 17-43 / 14-41
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 0.0072 4-43 / 18-57
PF01381.21 Helix-turn-helix 0.0074 17-43 / 7-33

Annotations of the NCBI proteins of this PHROG


4:hypothetical protein 1:helix-turn-helix DNA binding domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0016987 sigma factor activity
GO:0019069 viral capsid assembly
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0005622 intracellular
GO:0006352 DNA-templated transcription, initiation
GO:0006355 regulation of transcription, DNA-templated
GO:0043565 sequence-specific DNA binding
GO:0004803 transposase activity
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0003700 DNA binding transcription factor activity
GO:0005524 ATP binding
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity

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