phrog_18104 is made of 5 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
58.6 62 57


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_025471_p63 YP_009104300.1 putative HTH-XRE transcriptional regulator NC_025471 Idiomarinaceae phage Phi1M2-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_025439_p54 YP_009100961.1 putative HTH transcription regulator, XRE family NC_025439 Idiomarinaceae phage 1N2-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_028819_p58 YP_009200244.1 hypothetical protein NC_028819 Pseudoalteromonas phage H103 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KU356690_p49 AMD43436.1 hypothetical protein KU356690 Pseudomonas phage ZC03 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
KU356691_p44 AMD43512.1 hypothetical protein KU356691 Pseudomonas phage ZC08 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2166 70 N4-like RNA polymerase DNA, RNA and nucleotide metabolism 2 1.58E-11 1.92
phrog_2051 73 RNA polymerase DNA, RNA and nucleotide metabolism 2 1.79E-11 1.87
phrog_3022 47 DNA primase DNA, RNA and nucleotide metabolism 2 4.67E-12 2.45

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11145 DNA binding protein DNA, RNA and nucleotide metabolism 94.6 0.0027 15-55 / 3-43
phrog_1124 transcriptional regulator transcription regulation 91.2 0.038 16-51 / 22-59
phrog_1373 transcriptional regulator transcription regulation 97.4 5E-07 5-55 / 34-86
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 96.3 5.9E-05 12-54 / 20-64
phrog_147 transcriptional regulator transcription regulation 94.5 0.003 11-52 / 11-56
phrog_1529 no annotation unknown function 96.9 6.5E-06 5-56 / 6-61
phrog_2136 no annotation unknown function 93.1 0.012 15-53 / 43-82
phrog_2328 transcriptional repressor transcription regulation 94.3 0.0037 15-51 / 30-66
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.2 0.00099 14-53 / 38-78
phrog_23446 no annotation unknown function 95.5 0.00061 4-48 / 5-49
phrog_2439 transcriptional regulator transcription regulation 96.0 0.00015 3-54 / 7-60
phrog_2538 terminase small subunit head and packaging 92.5 0.019 15-36 / 21-42
phrog_25916 no annotation unknown function 97.1 2.4E-06 10-57 / 46-94
phrog_2967 transcriptional regulator transcription regulation 96.4 5.5E-05 16-54 / 24-63
phrog_296 DNA transposition protein integration and excision 92.1 0.024 14-56 / 15-58
phrog_3037 transcriptional repressor transcription regulation 92.7 0.017 5-52 / 15-66
phrog_3557 transcriptional regulator transcription regulation 90.5 0.054 6-48 / 13-60
phrog_35 transcriptional repressor transcription regulation 95.4 0.00066 1-49 / 2-49
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.6 0.00043 17-54 / 24-61
phrog_3949 transcriptional repressor transcription regulation 92.7 0.016 15-53 / 30-67
phrog_3 transcriptional repressor transcription regulation 97.4 6E-07 4-53 / 5-55
phrog_409 transcriptional regulator transcription regulation 94.8 0.0021 2-35 / 1-32
phrog_4268 transcriptional repressor transcription regulation 97.3 9.4E-07 12-56 / 45-89
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.6 0.0027 17-54 / 22-59
phrog_4583 transcriptional repressor transcription regulation 93.8 0.0067 5-52 / 13-62
phrog_4779 transcriptional regulator transcription regulation 94.8 0.002 2-53 / 1-56
phrog_4 transcriptional repressor transcription regulation 95.7 0.00033 7-53 / 4-52
phrog_5414 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.2 0.011 18-53 / 25-60
phrog_6223 transcriptional repressor transcription regulation 96.8 8.6E-06 10-54 / 14-59
phrog_638 transcriptional regulator transcription regulation 96.3 7.8E-05 14-53 / 17-56
phrog_66 excisionase and transcriptional regulator integration and excision 95.3 0.00085 14-55 / 10-59
phrog_6831 transcriptional regulator transcription regulation 97.5 3.3E-07 1-54 / 1-58
phrog_7126 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.4 0.0094 6-52 / 21-69
phrog_7241 transcriptional regulator transcription regulation 95.5 0.0006 12-53 / 71-114
phrog_725 CII-like regulator transcription regulation 96.0 0.00016 5-55 / 19-66
phrog_8898 no annotation unknown function 92.2 0.023 2-42 / 1-44
phrog_8 transcriptional regulator transcription regulation 97.2 1.2E-06 12-53 / 13-52
phrog_9103 transcriptional repressor transcription regulation 95.6 0.0005 14-54 / 21-61
phrog_925 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.1 0.0013 1-42 / 3-46
phrog_9425 transcriptional repressor transcription regulation 95.6 0.00044 5-55 / 10-63
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 92.0 0.025 6-35 / 11-40

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01381.21 Helix-turn-helix 2E-10 14-59 / 10-55
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 3.9E-10 14-60 / 12-58
PF05339.10 Protein of unknown function (DUF739) 5.8E-10 14-59 / 17-62
PF13744.5 Helix-turn-helix domain 6.9E-10 14-60 / 32-79
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 8.7E-10 4-59 / 15-75
PF13443.5 Cro/C1-type HTH DNA-binding domain 1.3E-09 14-60 / 11-60
PF13413.5 Helix-turn-helix domain 1.5E-09 14-57 / 10-59
PF12844.6 Helix-turn-helix domain 4.4E-09 14-60 / 13-59
PF14590.5 Domain of unknown function (DUF4447) 4.9E-09 6-59 / 14-69
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 5E-09 14-60 / 83-128
PF13560.5 Helix-turn-helix domain 2.7E-08 14-59 / 15-63
PF08667.9 BetR domain 3.8E-08 14-60 / 19-69
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 7.5E-08 15-59 / 10-54
PF04645.11 Protein of unknown function, DUF603 9.4E-08 5-50 / 13-60
PF05269.10 Bacteriophage CII protein 1.3E-07 14-60 / 24-68
PF08965.9 Domain of unknown function (DUF1870) 3.9E-07 6-41 / 8-44
PF13693.5 Winged helix-turn-helix DNA-binding 9.9E-07 14-59 / 16-58
PF14549.5 DNA-binding transcriptional regulator Cro 1.5E-06 15-58 / 11-51
PF00356.20 Bacterial regulatory proteins, lacI family 2.4E-06 16-41 / 2-27
PF12116.7 Stage III sporulation protein D 4.4E-06 14-55 / 20-62
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 9.4E-06 14-52 / 127-165
PF02376.14 CUT domain 7.2E-05 14-59 / 21-65
PF10654.8 Protein of unknown function (DUF2481) 9.8E-05 13-37 / 80-104
PF00376.22 MerR family regulatory protein 0.00045 17-37 / 3-23
PF08535.9 KorB domain 0.0008 14-37 / 4-27
PF06806.11 Putative excisionase (DUF1233) 0.0011 14-36 / 10-32
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.0012 14-37 / 14-37
PF04552.12 Sigma-54, DNA binding domain 0.0012 13-37 / 48-72
PF17443.1 Uncharacterized protein pXO2-72 0.0014 14-36 / 9-31
PF02042.14 RWP-RK domain 0.0015 14-36 / 13-35
PF07278.10 Protein of unknown function (DUF1441) 0.0016 14-38 / 2-26
PF01371.18 Trp repressor protein 0.0017 14-37 / 49-72
PF13591.5 MerR HTH family regulatory protein 0.0021 15-36 / 2-23
PF13411.5 MerR HTH family regulatory protein 0.0025 16-36 / 3-23
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.0032 14-35 / 4-25
PF09035.9 Excisionase from transposon Tn916 0.0036 14-34 / 16-36
PF06892.10 Phage regulatory protein CII (CP76) 0.0036 14-53 / 20-61
PF02954.18 Bacterial regulatory protein, Fis family 0.0045 14-34 / 17-37
PF07141.10 Putative bacteriophage terminase small subunit 0.0045 14-36 / 32-54
PF07506.10 RepB plasmid partitioning protein 0.0056 14-36 / 22-44
PF07037.10 Putative transcription regulator (DUF1323) 0.0064 15-36 / 2-23
PF10743.8 Regulatory phage protein cox 0.0066 14-37 / 12-35
PF06322.10 Phage NinH protein 0.0069 14-37 / 17-40
PF04936.11 Protein of unknown function (DUF658) 0.0081 14-36 / 15-37
PF08765.10 Mor transcription activator family 0.0089 14-37 / 73-96
PF07471.11 Phage DNA packaging protein Nu1 0.0096 14-36 / 3-25

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein 1:HTH-XRE transcriptional regulator 1:HTH transcription regulator, XRE family 1:protein of an unannotated phage

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005634 nucleus
GO:0005524 ATP binding
GO:0003700 DNA binding transcription factor activity
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding
GO:0006355 regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0045892 negative regulation of transcription, DNA-templated
GO:0019069 viral capsid assembly

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