phrog_18223 is made of 5 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
153.8 158 158


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
JF957059_p80 AEJ92286.1 hypothetical protein JF957059 Mycobacterium virus Optimus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
JF937101_p83 AEK09466.1 hypothetical protein JF937101 Mycobacterium virus Littlee Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
JF937090_p87 AEK08144.1 hypothetical protein JF937090 Mycobacterium virus Baka Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_004688_p86 NP_818387.1 gp88 NC_004688 Mycobacterium virus Omega Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_026584_p85 YP_009124038.1 hypothetical protein NC_026584 Mycobacterium phage Minerva Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
no colocalized PHROGS                                                                                          

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_186 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 92.8 0.015 15-88 / 2-84
phrog_270 replication initiation protein DNA, RNA and nucleotide metabolism 90.3 0.057 18-107 / 3-91
phrog_428 replication initiation protein DNA, RNA and nucleotide metabolism 92.1 0.025 13-95 / 6-90

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04492.12 Bacteriophage replication protein O 2.3E-07 32-90 / 24-85
PF06970.10 Replication initiator protein A (RepA) N-terminus 5.5E-06 20-78 / 2-75
PF16221.4 winged helix-turn-helix 5.8E-06 36-86 / 32-78
PF02319.19 E2F/DP family winged-helix DNA-binding domain 1.2E-05 52-88 / 23-57
PF04079.15 Segregation and condensation complex subunit ScpB 2E-05 31-91 / 79-131
PF03428.12 Replication protein C N-terminal domain 2.3E-05 25-90 / 33-107
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 2.4E-05 33-87 / 11-60
PF05584.10 Sulfolobus plasmid regulatory protein 2.5E-05 33-89 / 4-53
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 2.7E-05 33-88 / 6-56
PF09012.9 FeoC like transcriptional regulator 2.7E-05 53-91 / 15-51
PF05732.10 Firmicute plasmid replication protein (RepL) 2.8E-05 31-88 / 50-109
PF03965.15 Penicillinase repressor 3E-05 36-89 / 4-58
PF01978.18 Sugar-specific transcriptional regulator TrmB 3.6E-05 33-89 / 6-57
PF08222.10 CodY helix-turn-helix domain 4E-05 53-88 / 5-38
PF08784.10 Replication protein A C terminal 4.1E-05 32-88 / 37-95
PF07381.10 Winged helix DNA-binding domain (DUF1495) 4.1E-05 33-89 / 7-69
PF01090.18 Ribosomal protein S19e 5.6E-05 39-90 / 55-116
PF09114.9 Transcription factor MotA, activation domain 6.7E-05 32-88 / 13-65
PF12802.6 MarR family 6.8E-05 53-89 / 22-56
PF14557.5 Putative AphA-like transcriptional regulator 7.1E-05 32-89 / 5-68
PF09681.9 N-terminal phage replisome organiser (Phage_rep_org_N) 7.4E-05 53-105 / 54-101
PF13463.5 Winged helix DNA-binding domain 7.9E-05 53-88 / 18-51
PF01047.21 MarR family 8.3E-05 53-89 / 18-52
PF04182.11 B-block binding subunit of TFIIIC 8.3E-05 38-89 / 5-53
PF03551.13 Transcriptional regulator PadR-like family 9.6E-05 52-89 / 14-51
PF14277.5 Domain of unknown function (DUF4364) 0.00011 52-87 / 15-52
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.00012 33-91 / 6-59
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 0.00014 39-91 / 5-55
PF01475.18 Ferric uptake regulator family 0.00014 33-90 / 5-63
PF02002.16 TFIIE alpha subunit 0.00015 36-90 / 13-62
PF05158.11 RNA polymerase Rpc34 subunit 0.00017 32-89 / 89-143
PF06163.10 Bacterial protein of unknown function (DUF977) 0.00017 36-89 / 13-61
PF13601.5 Winged helix DNA-binding domain 0.00018 53-89 / 15-49
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 0.00019 33-88 / 6-60
PF14394.5 Domain of unknown function (DUF4423) 0.0002 53-89 / 37-73
PF11313.7 Protein of unknown function (DUF3116) 0.0002 53-90 / 21-63
PF13730.5 Helix-turn-helix domain 0.00024 34-84 / 4-52
PF01726.15 LexA DNA binding domain 0.00024 53-88 / 26-60
PF07848.11 PaaX-like protein 0.00025 53-88 / 21-57
PF09904.8 Winged helix-turn helix 0.00026 52-87 / 21-54
PF14502.5 Helix-turn-helix domain 0.00026 52-88 / 6-40
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00029 52-88 / 18-52
PF09824.8 ArsR transcriptional regulator 0.0003 35-87 / 17-61
PF02082.19 Transcriptional regulator 0.00033 53-87 / 25-57
PF14947.5 Winged helix-turn-helix 0.00036 53-88 / 17-50
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.00039 52-88 / 24-58
PF15977.4 Winged helix-turn-helix DNA binding 0.0004 52-88 / 23-57
PF13412.5 Winged helix-turn-helix DNA-binding 0.0004 53-84 / 18-47
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 0.00041 33-88 / 3-63
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.00044 52-88 / 21-55
PF09202.10 Rio2, N-terminal 0.00045 52-88 / 24-58
PF12840.6 Helix-turn-helix domain 0.00052 36-88 / 9-54
PF01022.19 Bacterial regulatory protein, arsR family 0.00059 53-84 / 17-46
PF09339.9 IclR helix-turn-helix domain 0.00064 53-87 / 19-51
PF09639.9 YjcQ protein 0.00071 52-89 / 16-53
PF01638.16 HxlR-like helix-turn-helix 0.0008 53-89 / 20-55
PF05331.10 Protein of unknown function (DUF742) 0.00091 32-89 / 38-88
PF09182.9 Bacterial purine repressor, N-terminal 0.00094 52-88 / 20-59
PF00392.20 Bacterial regulatory proteins, gntR family 0.00095 54-88 / 26-58
PF02295.16 Adenosine deaminase z-alpha domain 0.00099 53-88 / 19-53
PF13034.5 Protein of unknown function (DUF3895) 0.00098 37-90 / 5-69
PF10711.8 Hypothetical protein (DUF2513) 0.001 53-90 / 19-58
PF06969.15 HemN C-terminal domain 0.0011 53-87 / 21-54
PF02334.15 Replication terminator protein 0.0013 53-89 / 32-75
PF13545.5 Crp-like helix-turn-helix domain 0.0013 52-86 / 27-59
PF03297.14 S25 ribosomal protein 0.0015 52-88 / 56-90
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0016 53-87 / 18-50
PF08220.11 DeoR-like helix-turn-helix domain 0.0018 53-87 / 15-47
PF04703.11 FaeA-like protein 0.0018 53-88 / 15-48
PF01418.16 Helix-turn-helix domain, rpiR family 0.0019 32-88 / 13-68
PF01316.20 Arginine repressor, DNA binding domain 0.002 53-89 / 20-56
PF16864.4 Dimerisation domain 0.0028 53-87 / 33-65
PF00325.19 Bacterial regulatory proteins, crp family 0.0029 53-84 / 3-32
PF08461.9 Ribonuclease R winged-helix domain 0.0031 53-88 / 13-51
PF07900.10 Protein of unknown function (DUF1670) 0.0035 52-88 / 95-129
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.004 54-87 / 13-47
PF11972.7 HTH DNA binding domain 0.0053 53-85 / 14-41
PF08279.11 HTH domain 0.0067 53-82 / 16-43
PF08535.9 KorB domain 0.0074 53-89 / 4-38

Annotations of the NCBI proteins of this PHROG


5:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0009378 four-way junction helicase activity
GO:0007131 reciprocal meiotic recombination
GO:0006260 DNA replication
GO:0009289 pilus
GO:0005622 intracellular
GO:0006383 transcription by RNA polymerase III
GO:0004674 protein serine/threonine kinase activity
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005840 ribosome
GO:0006274 DNA replication termination
GO:0003700 DNA binding transcription factor activity
GO:0006468 protein phosphorylation
GO:0003677 DNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006310 DNA recombination
GO:0006355 regulation of transcription, DNA-templated
GO:0051304 chromosome separation
GO:0006412 translation
GO:0006525 arginine metabolic process
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0004252 serine-type endopeptidase activity
GO:0006281 DNA repair
GO:0005524 ATP binding
GO:0006276 plasmid maintenance
GO:0006508 proteolysis
GO:0005666 DNA-directed RNA polymerase III complex

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