phrog_18248 is made of 5 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
267 279 264


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_028854_p38 YP_009203483.1 transcriptional regulator NC_028854 Paenibacillus phage Sitara Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Sitaravirus.
KP296794_p30 AJK27889.1 transcriptional regulator KP296794 Bacteriophage Redbud Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Sitaravirus; unclassified Sitaravirus.
MG727701_p41 AUS03858.1 helix-turn-helix domain Cro/C1-type transcriptional regulator MG727701 Paenibacillus phage Leyra Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Sitaravirus; unclassified Sitaravirus.
NC_028758_p30 YP_009195220.1 helix-turn-helix domain protein NC_028758 Paenibacillus phage HB10c2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Sitaravirus.
NC_029084_p30 YP_009224896.1 DNA-binding protein NC_029084 Paenibacillus phage Rani Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Sitaravirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1 5879 integrase integration and excision 5 7.75E-14 4.23

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1994 DNA binding protein DNA, RNA and nucleotide metabolism 95.2 0.00099 5-73 / 2-72
phrog_2967 transcriptional regulator transcription regulation 93.8 0.0064 4-66 / 10-75
phrog_3 transcriptional repressor transcription regulation 94.3 0.0038 5-59 / 6-62
phrog_8 transcriptional regulator transcription regulation 97.7 5.5E-08 3-65 / 2-64

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 8.7E-06 12-53 / 5-46
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.00023 22-77 / 3-60
PF01381.21 Helix-turn-helix 0.00014 23-72 / 2-53
PF13413.5 Helix-turn-helix domain 0.00031 23-71 / 2-58
PF13744.5 Helix-turn-helix domain 0.00014 15-74 / 16-78
PF05339.10 Protein of unknown function (DUF739) 0.00015 18-74 / 4-62
PF12844.6 Helix-turn-helix domain 0.00042 22-75 / 4-59
PF14590.5 Domain of unknown function (DUF4447) 7.5E-05 15-76 / 5-71
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.00092 17-75 / 69-128
PF13560.5 Helix-turn-helix domain 0.00095 18-70 / 2-57
PF04645.11 Protein of unknown function, DUF603 0.00015 82-132 / 10-60
PF08667.9 BetR domain 0.0016 15-77 / 3-71
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.00029 22-76 / 2-61
PF08965.9 Domain of unknown function (DUF1870) 0.0028 19-53 / 3-39
PF05269.10 Bacteriophage CII protein 0.00039 85-149 / 16-71
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.0013 24-76 / 3-56
PF13693.5 Winged helix-turn-helix DNA-binding 0.0022 20-76 / 5-60
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0017 83-135 / 117-166
PF00157.16 Pou domain - N-terminal to homeobox domain 0.0039 83-135 / 11-64
PF14549.5 DNA-binding transcriptional regulator Cro 0.0022 23-74 / 3-52
PF00356.20 Bacterial regulatory proteins, lacI family 0.0024 95-135 / 1-39
PF12116.7 Stage III sporulation protein D 0.0031 91-135 / 18-60
PF02376.14 CUT domain 0.0032 15-76 / 5-67
PF10654.8 Protein of unknown function (DUF2481) 0.0058 90-116 / 78-103
PF04936.11 Protein of unknown function (DUF658) 0.0069 30-116 / 14-111

Annotations of the NCBI proteins of this PHROG


2:transcriptional regulator 1:helix-turn-helix domain protein 1:DNA-binding protein 1:helix-turn-helix domain Cro/C1-type transcriptional regulator

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0045893 positive regulation of transcription, DNA-templated

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