phrog_18342 is made of 5 protein sequences and is annotated as "transcriptional repressor"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
120.2 124 120


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p158151 no NCBI prot ID no annotation VI_11365 Gammaproteobacteria_gi_544815322 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KT898133_p36 ALN97556.1 HTH_XRE-family like protein KT898133 Aeromonas phage phiARM81ld Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
p244919 no NCBI prot ID no annotation VI_12013 Gammaproteobacteria_gi_410591407_12916_45167 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Bielevirus; Aeromonas virus phiO18P.
p242371 no NCBI prot ID no annotation VI_09647 Gammaproteobacteria_gi_484118852_278124_310736 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Bielevirus; Aeromonas virus phiO18P.
p230010 no NCBI prot ID no annotation VI_03658 Gammaproteobacteria_gi_507519518_4403312_4437141 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Bielevirus; Aeromonas virus phiO18P.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3282 44 sigma factor transcription regulation 1 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10045 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.8 0.029 31-81 / 21-66
phrog_101 CII-like transcriptional activator transcription regulation 93.7 0.0077 23-73 / 16-68
phrog_13326 no annotation unknown function 92.5 0.019 29-104 / 16-88
phrog_1373 transcriptional regulator transcription regulation 95.4 0.00074 19-79 / 33-91
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 93.4 0.0097 25-76 / 18-67
phrog_14025 no annotation unknown function 91.6 0.032 29-54 / 29-54
phrog_1702 transcriptional repressor transcription regulation 94.4 0.0035 21-80 / 17-77
phrog_18318 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.5 0.033 9-76 / 21-91
phrog_2328 transcriptional repressor transcription regulation 95.6 0.00048 19-79 / 17-75
phrog_2439 transcriptional regulator transcription regulation 95.1 0.0013 21-81 / 10-68
phrog_2967 transcriptional regulator transcription regulation 96.6 2.6E-05 20-79 / 11-69
phrog_296 DNA transposition protein integration and excision 94.2 0.0043 20-55 / 4-39
phrog_3218 terminase small subunit head and packaging 92.0 0.025 26-55 / 29-58
phrog_35 transcriptional repressor transcription regulation 95.7 0.00035 30-87 / 13-69
phrog_3949 transcriptional repressor transcription regulation 94.5 0.003 32-79 / 30-74
phrog_3 transcriptional repressor transcription regulation 97.9 1.6E-08 19-81 / 5-65
phrog_409 transcriptional regulator transcription regulation 94.7 0.0023 24-69 / 5-44
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.3 0.004 34-80 / 22-66
phrog_4583 transcriptional repressor transcription regulation 97.1 2.4E-06 20-82 / 13-73
phrog_4779 transcriptional regulator transcription regulation 95.1 0.0012 21-54 / 5-38
phrog_4 transcriptional repressor transcription regulation 96.0 0.00015 28-83 / 12-63
phrog_5301 transcriptional repressor transcription regulation 94.3 0.0039 27-74 / 20-67
phrog_534 DNA binding protein DNA, RNA and nucleotide metabolism 90.5 0.054 31-62 / 26-57
phrog_6223 transcriptional repressor transcription regulation 91.2 0.039 27-56 / 14-43
phrog_638 transcriptional regulator transcription regulation 94.2 0.0042 32-78 / 18-62
phrog_725 CII-like regulator transcription regulation 94.6 0.0027 30-75 / 27-67
phrog_7676 no annotation unknown function 94.1 0.0048 25-73 / 11-59
phrog_769 transcriptional repressor transcription regulation 95.2 0.001 20-81 / 15-71
phrog_7950 transcriptional repressor transcription regulation 93.4 0.0094 20-51 / 12-43
phrog_8 transcriptional regulator transcription regulation 97.7 6.6E-08 21-84 / 5-64

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 9.7E-10 16-81 / 7-76
PF13744.5 Helix-turn-helix domain 3E-09 15-81 / 14-79
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 1.4E-08 24-84 / 3-61
PF01381.21 Helix-turn-helix 1.7E-08 26-79 / 3-54
PF13443.5 Cro/C1-type HTH DNA-binding domain 3.8E-08 25-83 / 3-62
PF05339.10 Protein of unknown function (DUF739) 3.9E-08 22-81 / 6-63
PF13413.5 Helix-turn-helix domain 4.3E-08 26-78 / 3-59
PF14590.5 Domain of unknown function (DUF4447) 4.6E-08 19-83 / 7-72
PF12844.6 Helix-turn-helix domain 5E-08 24-83 / 4-61
PF04645.11 Protein of unknown function, DUF603 1.3E-07 17-71 / 5-60
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 1.9E-07 20-82 / 70-129
PF13560.5 Helix-turn-helix domain 1.9E-07 21-80 / 3-63
PF08667.9 BetR domain 4.3E-07 19-84 / 5-72
PF08965.9 Domain of unknown function (DUF1870) 1.2E-06 21-58 / 3-42
PF05269.10 Bacteriophage CII protein 1.3E-06 25-83 / 16-70
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 1.7E-06 27-83 / 4-57
PF13693.5 Winged helix-turn-helix DNA-binding 4.2E-06 23-83 / 6-61
PF14549.5 DNA-binding transcriptional regulator Cro 4.4E-06 25-80 / 3-52
PF12116.7 Stage III sporulation protein D 1.7E-05 29-75 / 16-61
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 1.8E-05 22-73 / 116-165
PF10654.8 Protein of unknown function (DUF2481) 2.6E-05 29-57 / 77-105
PF00157.16 Pou domain - N-terminal to homeobox domain 3.1E-05 18-74 / 6-64
PF02376.14 CUT domain 5.3E-05 19-82 / 7-67
PF00356.20 Bacterial regulatory proteins, lacI family 7.7E-05 34-58 / 1-25
PF08535.9 KorB domain 0.00066 31-57 / 2-28
PF02042.14 RWP-RK domain 0.0015 26-56 / 6-36
PF07506.10 RepB plasmid partitioning protein 0.0026 23-56 / 13-45
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.0034 31-57 / 12-38
PF04552.12 Sigma-54, DNA binding domain 0.0036 29-57 / 45-73
PF06322.10 Phage NinH protein 0.0038 26-57 / 10-41
PF06806.11 Putative excisionase (DUF1233) 0.0037 31-56 / 8-33
PF00376.22 MerR family regulatory protein 0.0039 35-57 / 2-24
PF02954.18 Bacterial regulatory protein, Fis family 0.0044 29-54 / 13-38
PF01371.18 Trp repressor protein 0.0045 29-57 / 45-73
PF07278.10 Protein of unknown function (DUF1441) 0.0049 32-56 / 1-25
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.0054 23-57 / 96-132
PF07141.10 Putative bacteriophage terminase small subunit 0.0059 30-55 / 29-54
PF17443.1 Uncharacterized protein pXO2-72 0.0067 31-56 / 7-32

Annotations of the NCBI proteins of this PHROG


1:HTH_XRE-family like protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003700 DNA binding transcription factor activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0043565 sequence-specific DNA binding
GO:0003677 DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0006355 regulation of transcription, DNA-templated
GO:0019069 viral capsid assembly
GO:0045892 negative regulation of transcription, DNA-templated

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