phrog_18375 is made of 5 protein sequences and is annotated as "DNA primase/helicase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
634.8 697 644


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p356848 no NCBI prot ID no annotation VI_04074 unknown_gi_487398877 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KC821604_p75 AGO47214.1 DNA primase/helicase/ VirE KC821604 Cellulophaga phage phiST Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cbastvirus; Cellulophaga virus ST.
KC821625_p69 AGO49080.1 DNA primase/helicase/ VirE KC821625 Cellulophaga phage phi13:1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cbastvirus; Cellulophaga virus ST; Cellulophaga phage phiST.
KC821621_p75 AGO48710.1 DNA primase/helicase/ VirE KC821621 Cellulophaga phage phi19:2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cbastvirus; Cellulophaga virus ST; Cellulophaga phage phiST.
NC_020842_p34 YP_007673416.1 hypothetical protein NC_020842 Cellulophaga phage phiST Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cbastvirus; Cellulophaga virus ST.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_20977 4 no annotation unknown function 4 0 1000
phrog_355 351 nucleoside 2-deoxyribosyltransferase DNA, RNA and nucleotide metabolism 4 2.21E-15 5.78

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_124 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 95.8 0.00026 377-456 / 16-73
phrog_14787 no annotation unknown function 91.4 0.034 5-179 / 4-188
phrog_15962 DNA primase DNA, RNA and nucleotide metabolism 96.5 2.9E-05 20-184 / 28-179
phrog_164 ParA-like partition protein DNA, RNA and nucleotide metabolism 90.2 0.059 377-420 / 5-45
phrog_19 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 99.1 4.6E-14 356-616 / 175-422
phrog_239 DNA primase/helicase DNA, RNA and nucleotide metabolism 99.7 1.4E-21 335-618 / 267-553
phrog_243 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 96.0 0.00018 352-577 / 13-223
phrog_28855 no annotation unknown function 99.2 2.2E-15 6-179 / 4-174
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 95.4 0.00064 484-543 / 132-185
phrog_296 DNA transposition protein integration and excision 91.9 0.027 373-558 / 89-218
phrog_3123 no annotation unknown function 91.5 0.034 487-578 / 432-518
phrog_5482 no annotation unknown function 99.2 3.4E-15 338-639 / 9-302
phrog_6891 ATPase other 95.1 0.0013 373-570 / 32-185
phrog_97 UvsX-like recombinase other 95.5 0.00058 376-580 / 57-237

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF03796.14 DnaB-like helicase C terminal domain 1.8E-16 359-613 / 2-255
PF08800.9 VirE N-terminal domain 4.6E-14 54-172 / 2-119
PF00154.20 recA bacterial DNA recombination protein 6.5E-12 356-593 / 30-246
PF06745.12 KaiC 3E-11 359-593 / 1-209
PF08423.10 Rad51 6.8E-11 356-591 / 16-237
PF09807.8 Elongation complex protein 6 8.1E-10 364-592 / 2-242
PF05625.10 PAXNEB protein 2.6E-08 357-578 / 17-275
PF07088.10 GvpD gas vesicle protein 4.3E-06 357-413 / 238-298
PF13481.5 AAA domain 1.3E-07 358-416 / 10-78
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 1.5E-05 362-413 / 1-49
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 3.5E-05 378-416 / 1-35
PF03846.13 Cell division inhibitor SulA 0.0001 364-417 / 10-66
PF13479.5 AAA domain 0.0001 375-395 / 2-22
PF05707.11 Zonular occludens toxin (Zot) 0.00024 377-413 / 2-37
PF05621.10 Bacterial TniB protein 0.0013 376-399 / 39-62
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.0023 375-400 / 4-29

Annotations of the NCBI proteins of this PHROG


3:DNA primase/helicase/ VirE 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K17680 PEO1 : twinkle protein [EC:3.6.4.12] no pathways 97 4

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0000155 phosphorelay sensor kinase activity
GO:0006260 DNA replication
GO:0003678 DNA helicase activity
GO:0009432 SOS response
GO:0043752 adenosylcobinamide kinase activity
GO:0004673 protein histidine kinase activity
GO:0006281 DNA repair
GO:0000166 nucleotide binding
GO:0003697 single-stranded DNA binding
GO:0016020 membrane
GO:0002098 tRNA wobble uridine modification
GO:0051188 cofactor biosynthetic process
GO:0051782 negative regulation of cell division
GO:0033588 Elongator holoenzyme complex
GO:0000160 phosphorelay signal transduction system
GO:0009236 cobalamin biosynthetic process
GO:0005524 ATP binding

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