phrog_1891 is made of 80 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
226.01 442 201


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_031036_p48 YP_009282389.1 hypothetical protein NC_031036 Lactobacillus phage PLE2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p221273 no NCBI prot ID no annotation VI_00848 Bacilli_gi_409995665_1041799_1076533 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p436778 no NCBI prot ID no annotation VI_05180 Bacilli_gi_518724447 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p221223 no NCBI prot ID no annotation VI_00834 Bacilli_gi_385818534_1045559_1080296 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p345644 no NCBI prot ID no annotation VI_05156 Bacilli_gi_511645692 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p221173 no NCBI prot ID no annotation VI_00966 Bacilli_gi_191636824_1043463_1078200 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p221124 no NCBI prot ID no annotation VI_00971 Bacilli_gi_385821700_1035449_1070186 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_028830_p45 YP_009201538.1 hypothetical protein NC_028830 Lactobacillus phage iA2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_031901_p44 YP_009320715.1 HNH_3 domain protein NC_031901 Streptococcus phage phiARI0131-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY065478_p20 APD23112.1 hypothetical protein KY065478 Streptococcus phage IPP38 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p228845 no NCBI prot ID no annotation VI_05302 Bacilli_gi_557375928 Viruses.
p237829 no NCBI prot ID no annotation VI_04402 Bacilli_gi_149012670_25250_58304 Viruses.
p226874 no NCBI prot ID no annotation VI_05303 Bacilli_gi_557376294_7048_41204 Viruses.
KY065476_p17 APD23042.1 hypothetical protein KY065476 Streptococcus phage IPP36 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_031913_p40 YP_009321991.1 HNH_3 domain protein NC_031913 Streptococcus phage phiARI0460-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY065468_p12 APD22566.1 hypothetical protein KY065468 Streptococcus phage IPP27 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY065472_p16 APD22779.1 hypothetical protein KY065472 Streptococcus phage IPP31 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p406868 no NCBI prot ID no annotation VI_04892 Bacilli_gi_421223748 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p211265 no NCBI prot ID no annotation VI_04901 Bacilli_gi_421241725 Viruses.
NC_031923_p38 YP_009322702.1 HNH_3 domain protein NC_031923 Streptococcus phage phiARI0468-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY065497_p20 APD24130.1 hypothetical protein KY065497 Streptococcus phage IPP61 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY065480_p20 APD23225.1 hypothetical protein KY065480 Streptococcus phage IPP40 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY065473_p19 APD22845.1 hypothetical protein KY065473 Streptococcus phage IPP32 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p159012 no NCBI prot ID no annotation VI_05276 Bacilli_gi_487638550_24494_64529 Viruses.
KJ417497_p20 AHN84607.1 hypothetical protein KJ417497 Streptococcus phage Spn1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p148631 no NCBI prot ID no annotation VI_04906 Bacilli_gi_421305463_0_41015 Viruses.
KY065450_p17 APD21583.1 hypothetical protein KY065450 Streptococcus phage IPP8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_008721_p16 YP_950566.1 hypothetical protein NC_008721 Streptococcus phage SMP Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p141180 no NCBI prot ID no annotation VI_04895 Bacilli_gi_421228548 Viruses; unclassified bacterial viruses.
KY065451_p16 APD21642.1 hypothetical protein KY065451 Streptococcus phage IPP9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY065488_p17 APD23644.1 hypothetical protein KY065488 Streptococcus phage IPP50 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p222077 no NCBI prot ID no annotation VI_04396 Bacilli_gi_148990169_4745_39384 Viruses.
KY065466_p13 APD22464.1 hypothetical protein KY065466 Streptococcus phage IPP25 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p422225 no NCBI prot ID no annotation VI_05280 Bacilli_gi_487648513 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY065452_p17 APD21706.1 hypothetical protein KY065452 Streptococcus phage IPP10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY065496_p17 APD24064.1 hypothetical protein KY065496 Streptococcus phage IPP60 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p23036 no NCBI prot ID no annotation VI_12315 Negativicutes_gi_520878529 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p22803 no NCBI prot ID no annotation VI_12311 Negativicutes_gi_522416322 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p49213 no NCBI prot ID no annotation VI_05491 Bacteroidia_gi_293372908_329_57889 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p26145 no NCBI prot ID no annotation VI_01015 Bacteroidia_gi_423298834_868952_940205 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p25801 no NCBI prot ID no annotation VI_05494 Bacteroidia_gi_482849993_161755_233136 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p120088 no NCBI prot ID no annotation VI_06626 Gammaproteobacteria_gi_257455533_8222_51655 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p130651 no NCBI prot ID no annotation VI_06329 Fusobacteriia_gi_34762154 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p139587 no NCBI prot ID no annotation VI_04872 Bacilli_gi_420225008_3736_45574 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p125173 no NCBI prot ID no annotation VI_04833 Bacilli_gi_419768752 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p276738 no NCBI prot ID no annotation VI_04460 Bacilli_gi_258427119 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p151897 no NCBI prot ID no annotation VI_00910 Bacilli_gi_484080317 Viruses.
p374250 no NCBI prot ID no annotation VI_06678 Gammaproteobacteria_gi_307251317 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_004820_p29 NP_852509.1 hypothetical protein NC_004820 Bacillus phage phBC6A51 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p170676 no NCBI prot ID no annotation VI_06333 Fusobacteriia_gi_419841405 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p341707 no NCBI prot ID no annotation VI_05047 Bacilli_gi_407980662 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_028915_p32 YP_009209155.1 HNH endonuclease domain protein NC_028915 Staphylococcus phage B236 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Phietavirus; unclassified Phietavirus.
p58949 no NCBI prot ID no annotation VI_01282 Clostridia_gi_187932320_2821332_2873931 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KC348598_p42 AGF87332.1 putative HNH endonuclease KC348598 Streptococcus phage phi20c Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_018281_p54 YP_006560995.1 hypothetical protein NC_018281 Staphylococcus virus IPLA5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Phietavirus.
p97507 no NCBI prot ID no annotation VI_04032 Negativicutes_gi_485071342 Viruses.
p254317 no NCBI prot ID no annotation VI_04508 Bacilli_gi_301300708 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p164778 no NCBI prot ID no annotation VI_04867 Bacilli_gi_420218063_0_39510 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p262570 no NCBI prot ID no annotation VI_06575 Gammaproteobacteria_gi_209953824_71393_102145 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p418493 no NCBI prot ID no annotation VI_06330 Fusobacteriia_gi_34763346 Viruses.
p135027 no NCBI prot ID no annotation VI_01360 Fusobacteriia_gi_224580831_44287_86520 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p226208 no NCBI prot ID no annotation VI_00940 Bacilli_gi_522837163 Viruses.
p396473 no NCBI prot ID no annotation VI_08402 Gammaproteobacteria_gi_484206216 Viruses.
p225038 no NCBI prot ID no annotation VI_03446 Gammaproteobacteria_gi_444350194_608268_642569 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p278318 no NCBI prot ID no annotation VI_00030 Actinobacteria_gi_548079438 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p84328 no NCBI prot ID no annotation VI_02552 Gammaproteobacteria_gi_490720375 Viruses.
p270211 no NCBI prot ID no annotation VI_02596 Gammaproteobacteria_gi_422597474_64764_94809 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p326217 no NCBI prot ID no annotation VI_07449 Gammaproteobacteria_gi_490683720 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p183924 no NCBI prot ID no annotation VI_07443 Gammaproteobacteria_gi_485473597_108249_146077 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p173518 no NCBI prot ID no annotation VI_09030 Gammaproteobacteria_gi_485055641_9395_48050 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p231660 no NCBI prot ID no annotation VI_01046 Bacteroidia_gi_484001862 Viruses.
p425418 no NCBI prot ID no annotation VI_11158 Gammaproteobacteria_gi_505462444 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Beetrevirus; Pseudomonas virus B3; Pseudomonas phage B3.
KY658678_p25 ARB13323.1 HNH endonuclease KY658678 Vibrio phage pVa-3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KX581098_p22 AOT27021.1 HNH endonuclease KX581098 Vibrio phage VaK Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p238674 no NCBI prot ID no annotation VI_06415 Gammaproteobacteria_gi_145629787 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p349705 no NCBI prot ID no annotation VI_07363 Gammaproteobacteria_gi_417846219 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p130707 no NCBI prot ID no annotation VI_06612 Gammaproteobacteria_gi_260583086 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p112944 no NCBI prot ID no annotation VI_02615 Gammaproteobacteria_gi_329124276_813_45072 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p55170 no NCBI prot ID no annotation VI_01077 Betaproteobacteria_gi_120608714_2556822_2610901 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p49728 no NCBI prot ID no annotation VI_01193 Clostridia_gi_336423913 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2044 74 RNA polymerase beta subunit DNA, RNA and nucleotide metabolism 64 4.76E-240 230.44
phrog_253 474 Mu Gam-like end protection DNA, RNA and nucleotide metabolism 29 4.48E-67 57.47
phrog_13069 8 no annotation unknown function 8 0 1000
phrog_17171 5 no annotation unknown function 5 0 1000
phrog_17069 5 no annotation unknown function 4 1.67E-19 9.9
phrog_3683 39 no annotation unknown function 4 9.55E-14 4.14
phrog_18726 5 no annotation unknown function 3 4.81E-15 5.44
phrog_16987 5 no annotation unknown function 2 5.51E-11 1.38
phrog_16199 6 no annotation unknown function 2 1.10E-10 1.08

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10730 HNH endonuclease DNA, RNA and nucleotide metabolism 95.3 0.00086 102-169 / 14-85
phrog_12324 intron-like DNA endonuclease DNA, RNA and nucleotide metabolism 97.1 2.8E-06 125-187 / 4-83
phrog_14101 transcriptional regulator transcription regulation 93.8 0.007 5-51 / 3-49
phrog_14913 HNH endonuclease DNA, RNA and nucleotide metabolism 94.3 0.0039 99-167 / 16-87
phrog_1492 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 5E-06 105-166 / 54-116
phrog_15471 HNH endonuclease DNA, RNA and nucleotide metabolism 98.3 6E-10 119-168 / 30-79
phrog_1872 endonuclease DNA, RNA and nucleotide metabolism 96.5 3.8E-05 105-166 / 38-97
phrog_19902 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 8.2E-06 66-164 / 47-132
phrog_20891 HNH endonuclease DNA, RNA and nucleotide metabolism 94.4 0.0033 102-162 / 120-185
phrog_323 transcriptional regulator, D5-like transcription regulation 92.2 0.023 5-48 / 46-89
phrog_3593 HNH endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0053 103-165 / 62-117
phrog_4578 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 6.4E-07 130-166 / 1-37
phrog_59 HNH endonuclease DNA, RNA and nucleotide metabolism 97.9 2.4E-08 105-168 / 38-100
phrog_6254 HNH endonuclease DNA, RNA and nucleotide metabolism 97.0 3.9E-06 102-165 / 20-81
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 97.4 5.4E-07 14-168 / 7-132
phrog_826 HNH endonuclease DNA, RNA and nucleotide metabolism 97.6 1.1E-07 104-169 / 31-97
phrog_959 HNH endonuclease DNA, RNA and nucleotide metabolism 98.0 5.8E-09 102-166 / 37-99
phrog_99 HNH endonuclease DNA, RNA and nucleotide metabolism 98.6 2.7E-11 95-168 / 32-97

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13392.5 HNH endonuclease 6.3E-11 179-222 / 2-44
PF05551.10 Zinc-binding loop region of homing endonuclease 6.8E-11 163-227 / 14-81
PF10548.8 P22AR C-terminal domain 2.4E-09 278-344 / 4-70
PF13921.5 Myb-like DNA-binding domain 0.00031 8-74 / 1-64
PF08914.10 Rap1 Myb domain 0.0065 5-44 / 2-47

Annotations of the NCBI proteins of this PHROG


19:hypothetical protein 3:HNH_3 domain protein 3:HNH endonuclease 1:HNH endonuclease domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
no GO term               

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