phrog_1936 is made of 79 protein sequences and is annotated as "MazF-like growth inhibitor"
Functional category: moron, auxiliary metabolic gene and host takeover


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
125.48 272 117


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p71246 no NCBI prot ID no annotation VI_01189 Clostridia_gi_283767241_16075_65536 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p15372 no NCBI prot ID no annotation VI_01194 Clostridia_gi_373121103_353147_435681 Viruses.
p78251 no NCBI prot ID no annotation VI_01154 Clostridia_gi_256402711_179985_228048 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p151474 no NCBI prot ID no annotation VI_01158 Clostridia_gi_224514969_26510_67213 Viruses.
p176213 no NCBI prot ID no annotation VI_01150 Clostridia_gi_324035913_481009_519433 Viruses.
MG711461_p50 AUV56402.1 MazF family toxin MG711461 Faecalibacterium phage FP_Lagaffe Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Lagaffevirus; Faecalibacterium virus Lagaffe.
p59367 no NCBI prot ID no annotation VI_01197 Clostridia_gi_355635008_30994_83331 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p17088 no NCBI prot ID no annotation VI_01301 Clostridia_gi_483984649 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
MG711465_p83 AUV56702.1 hypothetical protein MG711465 Faecalibacterium phage FP_Brigit Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Brigitvirus; Faecalibacterium virus Brigit.
MG765279_p123 AUV60188.1 hypothetical protein MG765279 Lactobacillus phage Semele Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Twortvirinae; Harbinvirus; Lactobacillus virus Semele.
MF787246_p90 ATG86401.1 mRNA interferase MF787246 Lactobacillus phage LpeD Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; unclassified Herelleviridae.
MG765277_p37 AUV59922.1 hypothetical protein MG765277 Lactobacillus phage Bacchae Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Twortvirinae; Harbinvirus; Lactobacillus virus Bacchae.
KX223815_p38 ANO57967.1 PemK family transcriptional regulator KX223815 Lactobacillus phage P1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tybeckvirinae; Maenadvirus; Lactobacillus virus P1.
MG765274_p61 AVH85635.1 hypothetical protein MG765274 Lactobacillus phage Maenad Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tybeckvirinae; Maenadvirus; Lactobacillus virus Maenad.
MG744354_p65 AUV57313.1 hypothetical protein MG744354 Lactobacillus phage Satyr Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tybeckvirinae; Maenadvirus; Lactobacillus virus Satyr.
MG765276_p74 AUV59834.1 hypothetical protein MG765276 Lactobacillus phage Nyseid Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tybeckvirinae; Lenusvirus; Lactobacillus virus Nyseid.
MG252693_p75 ATW59492.1 mRNA interferase MG252693 Lactobacillus phage Lenus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tybeckvirinae; Lenusvirus; Lactobacillus virus Lenus.
KU052488_p108 ALY06929.1 MazF family toxin-antitoxin system protein KU052488 Lactobacillus phage SA-C12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tybeckvirinae; Lenusvirus; Lactobacillus virus SAC12.
NC_010179_p56 YP_001642399.1 MazF-like protein NC_010179 Lactobacillus prophage Lj771 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p136152 no NCBI prot ID no annotation VI_05471 Bacilli_gi_395239076 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p48446 no NCBI prot ID no annotation VI_00872 Bacilli_gi_312977117_201829_259634 Viruses.
p55512 no NCBI prot ID no annotation VI_00454 Bacilli_gi_262046743_72999_126896 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p57106 no NCBI prot ID no annotation VI_00781 Bacilli_gi_551717241_407555_460919 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p56077 no NCBI prot ID no annotation VI_00457 Bacilli_gi_423321503_348617_402292 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p252347 no NCBI prot ID no annotation VI_06846 Gammaproteobacteria_gi_309797878 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p100894 no NCBI prot ID no annotation VI_04801 Bacilli_gi_377556685 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p12301 no NCBI prot ID no annotation VI_01198 Clostridia_gi_331640230_194003_280818 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p300376 no NCBI prot ID no annotation VI_01214 Clostridia_gi_546477851 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p239261 no NCBI prot ID no annotation VI_04851 Bacilli_gi_419819195_18643_51507 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p239227 no NCBI prot ID no annotation VI_04848 Bacilli_gi_419815797_18564_51428 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p149634 no NCBI prot ID no annotation VI_04846 Bacilli_gi_406588330 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p302589 no NCBI prot ID no annotation VI_04852 Bacilli_gi_480994456_0_25579 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p139218 no NCBI prot ID no annotation VI_05583 Betaproteobacteria_gi_484322655_389_42258 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p72786 no NCBI prot ID no annotation VI_05609 Betaproteobacteria_gi_433469085 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p242429 no NCBI prot ID no annotation VI_05684 Betaproteobacteria_gi_487562486 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p256938 no NCBI prot ID no annotation VI_00084 Alphaproteobacteria_gi_511098068_31297_62538 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p150056 no NCBI prot ID no annotation VI_05688 Betaproteobacteria_gi_487572903 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p213003 no NCBI prot ID no annotation VI_01051 Betaproteobacteria_gi_293398769 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p165159 no NCBI prot ID no annotation VI_05680 Betaproteobacteria_gi_487544895 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p162078 no NCBI prot ID no annotation VI_05687 Betaproteobacteria_gi_514983307 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p127699 no NCBI prot ID no annotation VI_06607 Gammaproteobacteria_gi_240948420 Viruses.
p186418 no NCBI prot ID no annotation VI_05679 Betaproteobacteria_gi_487542268 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p172169 no NCBI prot ID no annotation VI_05743 Betaproteobacteria_gi_421906670_10852_49676 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p408386 no NCBI prot ID no annotation VI_05691 Betaproteobacteria_gi_514982514 Viruses.
p318036 no NCBI prot ID no annotation VI_05715 Betaproteobacteria_gi_545068446 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p226538 no NCBI prot ID no annotation VI_04356 Alphaproteobacteria_gi_484042631 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p270162 no NCBI prot ID no annotation VI_01063 Betaproteobacteria_gi_223958736 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p160876 no NCBI prot ID no annotation VI_05670 Betaproteobacteria_gi_498489846 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p161704 no NCBI prot ID no annotation VI_05689 Betaproteobacteria_gi_487576318 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KY065496_p34 APD24081.1 transcriptional regulator KY065496 Streptococcus phage IPP60 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY065465_p29 APD22424.1 transcriptional regulator KY065465 Streptococcus phage IPP24 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p398287 no NCBI prot ID no annotation VI_04400 Bacilli_gi_149004388 Viruses.
p109494 no NCBI prot ID no annotation VI_00961 Bacilli_gi_289166909_398200_442838 Viruses.
p351391 no NCBI prot ID no annotation VI_04804 Bacilli_gi_418973915 Viruses; unclassified bacterial viruses.
p222092 no NCBI prot ID no annotation VI_04396 Bacilli_gi_148990169_4745_39384 Viruses.
p154802 no NCBI prot ID no annotation VI_00902 Bacilli_gi_483613946_212003_252391 Viruses.
p305675 no NCBI prot ID no annotation VI_05427 Bacilli_gi_565854743 Viruses; unclassified bacterial viruses.
NC_009812_p28 YP_001468667.1 gp28 NC_009812 Listeria phage B025 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p247248 no NCBI prot ID no annotation VI_05346 Bacilli_gi_544872557_209220_241322 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Triavirus; unclassified Triavirus; Staphylococcus phage StauST398-2.
p127442 no NCBI prot ID no annotation VI_04871 Bacilli_gi_420220190_3871_46499 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p88147 no NCBI prot ID no annotation VI_00840 Bacilli_gi_387601291_1596549_1643210 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p74948 no NCBI prot ID no annotation VI_00963 Bacilli_gi_70725001_1807036_1855693 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fibralongavirus; Staphylococcus virus 2638A; Staphylococcus phage 2638A.
NC_021323_p62 YP_008058826.1 hypothetical protein NC_021323 Staphylococcus phage StauST398-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Triavirus; unclassified Triavirus.
p79946 no NCBI prot ID no annotation VI_04788 Bacilli_gi_510813710_2326_50153 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p145234 no NCBI prot ID no annotation VI_05347 Bacilli_gi_544872726_414297_455585 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p13806 no NCBI prot ID no annotation VI_00993 Bacilli_gi_526444490 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p280962 no NCBI prot ID no annotation VI_05786 Clostridia_gi_485045070 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Clostridium phage c-st.
p12844 no NCBI prot ID no annotation VI_00893 Bacilli_gi_323650955 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_029073_p40 YP_009223747.1 PemK-like protein NC_029073 Geobacillus virus E3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p329143 no NCBI prot ID no annotation VI_04355 Alphaproteobacteria_gi_484042176 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p389824 no NCBI prot ID no annotation VI_03530 Gammaproteobacteria_gi_57014152_1776416_1791725 Viruses.
p23174 no NCBI prot ID no annotation VI_04007 Negativicutes_gi_312899164 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p407334 no NCBI prot ID no annotation VI_01272 Clostridia_gi_548199516 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p59407 no NCBI prot ID no annotation VI_00699 Bacilli_gi_507029665 Viruses.
p54475 no NCBI prot ID no annotation VI_01114 Betaproteobacteria_gi_485071427 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p706 no NCBI prot ID no annotation VI_01291 Clostridia_gi_512436336 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p54070 no NCBI prot ID no annotation VI_01167 Clostridia_gi_313116237 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_026609_p44 YP_009126486.1 growth inhibitor NC_026609 Lactobacillus phage Ldl1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tybeckvirinae; Lidleunavirus; Lactobacillus virus Ldl1.
p280964 no NCBI prot ID no annotation VI_05786 Clostridia_gi_485045070 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Clostridium phage c-st.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_4324 32 no annotation unknown function 25 1.77E-96 86.87
phrog_1281 116 no annotation unknown function 10 1.52E-28 18.94
phrog_9969 10 transcriptional regulator transcription regulation 8 1.23E-34 25.03
phrog_14545 7 no annotation unknown function 6 7.48E-28 18.25
phrog_4709 28 no annotation unknown function 4 4.30E-15 5.49
phrog_23668 3 no annotation unknown function 3 0 1000
phrog_29173 2 no annotation unknown function 2 0 1000
phrog_34936 2 no annotation unknown function 2 0 1000
phrog_33483 2 no annotation unknown function 2 0 1000
phrog_15982 6 no annotation unknown function 2 4.98E-11 1.42
phrog_29876 2 no annotation unknown function 2 0 1000
phrog_28654 2 no annotation unknown function 2 0 1000
phrog_36865 2 no annotation unknown function 2 0 1000
phrog_34292 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_13411 MazF-like growth inhibitor moron, auxiliary metabolic gene and host takeover 96.7 1.6E-05 2-94 / 1-92
phrog_1412 antitoxin mazE-like moron, auxiliary metabolic gene and host takeover 98.3 1E-09 2-115 / 53-224
phrog_15698 no annotation unknown function 97.5 3.4E-07 3-113 / 6-121
phrog_35650 MazF-like growth inhibitor moron, auxiliary metabolic gene and host takeover 99.2 3.9E-15 2-114 / 15-132
phrog_9567 MazF-like growth inhibitor moron, auxiliary metabolic gene and host takeover 98.2 1.1E-09 3-113 / 25-135

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF02452.16 PemK-like, MazF-like toxin of type II toxin-antitoxin system 1.3E-18 20-124 / 1-103
PF01845.16 CcdB protein 5.8E-17 21-125 / 1-99

Annotations of the NCBI proteins of this PHROG


8:hypothetical protein 2:mRNA interferase 2:transcriptional regulator 1:growth inhibitor 1:PemK family transcriptional regulator 1:MazF family toxin-antitoxin system protein 1:MazF family toxin 1:MazF-like protein 1:PemK-like protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K07171 mazF, ndoA, chpA : mRNA interferase MazF [EC:3.1.-.-] no pathways 243 41
K18841 chpB, chpBK : mRNA interferase ChpB [EC:3.1.-.-] no pathways 235 18

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0008657 DNA topoisomerase (ATP-hydrolyzing) inhibitor activity
GO:0006276 plasmid maintenance

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