phrog_20450 is made of 4 protein sequences and is annotated as "transcriptional repressor"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
219.25 336 187


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY965064_p43 ASJ79642.1 immunity repressor KY965064 Mycobacterium phage Pippy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_026588_p38 YP_009124590.1 immunity repressor NC_026588 Mycobacterium phage Squirty Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_031262_p41 YP_009303880.1 immunity repressor NC_031262 Mycobacterium phage Brocalys Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_031061_p44 YP_009286089.1 immunity repressor NC_031061 Gordonia phage Nymphadora Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nymbaxtervirinae; Nymphadoravirus; Gordonia virus Nymphadora.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_87 993 metallo-protease other 3 1.47E-12 2.95
phrog_25907 3 no annotation unknown function 1 4.44E-11 1.47

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_13730 transcriptional repressor transcription regulation 96.6 2.1E-05 39-125 / 27-117
phrog_3949 transcriptional repressor transcription regulation 93.5 0.009 19-149 / 6-152
phrog_4583 transcriptional repressor transcription regulation 91.2 0.038 44-83 / 28-68

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 4.4E-06 22-89 / 8-80
PF05339.10 Protein of unknown function (DUF739) 1.6E-05 28-86 / 7-64
PF13744.5 Helix-turn-helix domain 3.2E-05 27-85 / 21-79
PF01381.21 Helix-turn-helix 3.2E-05 39-83 / 9-54
PF14590.5 Domain of unknown function (DUF4447) 3.6E-05 25-86 / 8-71
PF13413.5 Helix-turn-helix domain 3.5E-05 39-82 / 9-59
PF13443.5 Cro/C1-type HTH DNA-binding domain 4.7E-05 39-87 / 10-62
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 4.9E-05 39-86 / 11-59
PF12844.6 Helix-turn-helix domain 7.3E-05 39-85 / 12-59
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.00012 27-86 / 72-129
PF13560.5 Helix-turn-helix domain 0.00019 28-84 / 5-63
PF05269.10 Bacteriophage CII protein 0.00025 39-89 / 23-72
PF08965.9 Domain of unknown function (DUF1870) 0.00028 27-80 / 4-58
PF04645.11 Protein of unknown function, DUF603 0.0003 23-75 / 6-60
PF08667.9 BetR domain 0.00045 25-87 / 6-71
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.00071 41-85 / 10-55
PF14549.5 DNA-binding transcriptional regulator Cro 0.0012 39-85 / 10-53
PF13693.5 Winged helix-turn-helix DNA-binding 0.002 29-86 / 7-60
PF00157.16 Pou domain - N-terminal to homeobox domain 0.0035 27-78 / 10-64
PF12116.7 Stage III sporulation protein D 0.0041 39-81 / 19-63
PF00356.20 Bacterial regulatory proteins, lacI family 0.0044 41-71 / 1-32
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0054 39-78 / 126-166

Annotations of the NCBI proteins of this PHROG


4:immunity repressor

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0045893 positive regulation of transcription, DNA-templated

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