phrog_20467 is made of 4 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
108.75 147 112


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_026590_p30 YP_009124773.1 DNA binding domain protein NC_026590 Mycobacterium phage Gaia Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gaiavirus.
MG812488_p29 AUX81955.1 transposase MG812488 Mycobacterium phage Frankie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
p90559 no NCBI prot ID no annotation VI_04116 Actinobacteria_gi_419962223 Viruses.
KJ410740_p56 AHV82181.1 hypothetical protein KJ410740 Synechococcus phage S-EIVl Viruses; unclassified bacterial viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
no colocalized PHROGS                                                                                          

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1033 ParB-like partition protein DNA, RNA and nucleotide metabolism 94.0 0.0053 63-91 / 134-162
phrog_1065 no annotation unknown function 90.9 0.044 73-97 / 102-126
phrog_11138 no annotation unknown function 91.6 0.031 53-94 / 90-131
phrog_11376 no annotation unknown function 96.3 5.8E-05 54-94 / 42-82
phrog_11420 DNA binding protein DNA, RNA and nucleotide metabolism 95.9 0.0002 54-95 / 9-50
phrog_1157 transposase integration and excision 96.7 1.6E-05 54-94 / 1-41
phrog_1190 RNA polymerase sigma factor transcription regulation 93.8 0.0065 33-94 / 109-177
phrog_1206 terminase small subunit head and packaging 91.0 0.042 61-97 / 7-44
phrog_12540 no annotation unknown function 94.3 0.0041 52-93 / 11-52
phrog_125 DNA invertase DNA, RNA and nucleotide metabolism 95.7 0.00034 60-96 / 148-184
phrog_12720 DNA binding protein DNA, RNA and nucleotide metabolism 92.5 0.019 68-95 / 44-74
phrog_12823 no annotation unknown function 92.1 0.024 54-91 / 12-49
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 95.1 0.0012 64-92 / 13-41
phrog_1373 transcriptional regulator transcription regulation 96.7 1.8E-05 66-99 / 40-73
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 94.3 0.0038 57-94 / 10-47
phrog_14131 DNA binding protein DNA, RNA and nucleotide metabolism 94.3 0.0037 70-94 / 124-148
phrog_141 terminase small subunit head and packaging 93.1 0.013 70-93 / 9-32
phrog_1468 transcriptional repressor transcription regulation 92.9 0.015 64-91 / 14-41
phrog_15152 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.4 0.054 53-93 / 29-69
phrog_151 transposase integration and excision 95.8 0.00029 55-94 / 7-47
phrog_1590 no annotation unknown function 92.6 0.017 24-92 / 19-84
phrog_16311 no annotation unknown function 91.3 0.036 53-90 / 3-40
phrog_16568 Ren-like exclusion protein moron, auxiliary metabolic gene and host takeover 90.7 0.048 50-95 / 53-99
phrog_1702 transcriptional repressor transcription regulation 91.9 0.027 56-92 / 14-49
phrog_1728 transcriptional regulator transcription regulation 92.0 0.025 66-93 / 12-39
phrog_1740 RNA polymerase sigma factor transcription regulation 96.6 2.4E-05 52-94 / 124-166
phrog_17599 no annotation unknown function 91.4 0.036 72-95 / 73-96
phrog_20634 no annotation unknown function 91.3 0.038 62-91 / 77-106
phrog_2104 no annotation unknown function 95.0 0.0016 49-97 / 39-85
phrog_2119 no annotation unknown function 94.7 0.0023 57-95 / 15-52
phrog_2308 no annotation unknown function 95.9 0.00024 55-94 / 1-40
phrog_2328 transcriptional repressor transcription regulation 91.6 0.032 62-95 / 19-53
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.1 0.00014 65-95 / 32-62
phrog_23834 no annotation unknown function 91.3 0.036 54-92 / 1-37
phrog_24399 no annotation unknown function 91.8 0.028 61-100 / 39-80
phrog_24603 no annotation unknown function 90.2 0.06 64-94 / 37-67
phrog_2538 terminase small subunit head and packaging 95.5 0.00055 53-94 / 2-43
phrog_2606 terminase small subunit head and packaging 92.7 0.017 62-97 / 11-49
phrog_2727 no annotation unknown function 90.0 0.065 58-96 / 13-51
phrog_27475 no annotation unknown function 91.6 0.031 54-93 / 1-40
phrog_296 DNA transposition protein integration and excision 95.2 0.0011 65-99 / 9-43
phrog_309 terminase small subunit head and packaging 95.0 0.0014 59-91 / 13-45
phrog_323 transcriptional regulator, D5-like transcription regulation 95.0 0.0014 54-95 / 4-40
phrog_3282 sigma factor transcription regulation 95.8 0.00028 55-93 / 18-55
phrog_3356 transposase integration and excision 91.1 0.041 53-94 / 29-70
phrog_3512 sigma factor transcription regulation 96.1 0.00013 54-94 / 66-106
phrog_351 RNA polymerase sigma factor transcription regulation 96.0 0.00019 53-94 / 174-218
phrog_357 transcriptional repressor transcription regulation 93.5 0.0089 62-93 / 16-47
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.1 0.00014 53-95 / 4-45
phrog_3736 no annotation unknown function 90.7 0.049 58-94 / 6-41
phrog_3757 no annotation unknown function 92.3 0.021 58-93 / 336-371
phrog_3803 RIIB lysis inhibitor lysis 90.8 0.047 54-91 / 49-86
phrog_3855 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.3 5.6E-05 55-95 / 64-104
phrog_3910 transcriptional regulator transcription regulation 96.4 5.3E-05 57-92 / 66-101
phrog_3 transcriptional repressor transcription regulation 95.5 0.00063 68-92 / 14-38
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 96.3 6.4E-05 63-99 / 13-49
phrog_4291 RNA-dependent RNA polymerase DNA, RNA and nucleotide metabolism 94.7 0.0022 46-92 / 859-905
phrog_4494 no annotation unknown function 95.3 0.00087 55-94 / 2-41
phrog_4538 no annotation unknown function 91.7 0.03 57-95 / 331-369
phrog_4583 transcriptional repressor transcription regulation 95.4 0.00067 64-95 / 17-48
phrog_4646 transposase integration and excision 95.3 0.00089 51-94 / 3-46
phrog_4779 transcriptional regulator transcription regulation 97.0 3E-06 56-92 / 2-36
phrog_517 HTH DNA binding protein DNA, RNA and nucleotide metabolism 98.2 1.5E-09 49-94 / 58-103
phrog_5229 no annotation unknown function 93.3 0.01 53-93 / 64-104
phrog_532 late transcriptional activator transcription regulation 92.2 0.023 34-95 / 64-121
phrog_5536 no annotation unknown function 97.4 5.7E-07 54-95 / 5-46
phrog_5751 terminase large subunit head and packaging 95.4 0.00069 61-99 / 9-47
phrog_5823 transcriptional regulator transcription regulation 91.0 0.043 55-90 / 4-37
phrog_597 DNA binding protein DNA, RNA and nucleotide metabolism 91.6 0.032 69-90 / 13-35
phrog_59 HNH endonuclease DNA, RNA and nucleotide metabolism 95.5 0.0006 70-98 / 111-139
phrog_609 RIIB lysis inhibitor lysis 95.0 0.0015 53-95 / 5-48
phrog_6156 endonuclease DNA, RNA and nucleotide metabolism 98.5 1.2E-10 53-99 / 17-63
phrog_6223 transcriptional repressor transcription regulation 95.9 0.00025 68-93 / 15-40
phrog_645 Rnase E DNA, RNA and nucleotide metabolism 95.7 0.00039 52-94 / 17-59
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 91.1 0.04 55-93 / 4-42
phrog_66 excisionase and transcriptional regulator integration and excision 93.2 0.011 71-93 / 10-32
phrog_6831 transcriptional regulator transcription regulation 96.6 2.1E-05 64-93 / 9-38
phrog_686 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.3 0.01 54-93 / 20-60
phrog_704 DNA repair exonuclease DNA, RNA and nucleotide metabolism 95.0 0.0015 55-95 / 5-42
phrog_7061 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.5 0.003 58-94 / 32-68
phrog_7067 terminase small subunit head and packaging 92.2 0.022 40-90 / 4-51
phrog_7241 transcriptional regulator transcription regulation 91.7 0.03 45-89 / 47-93
phrog_725 CII-like regulator transcription regulation 92.8 0.016 63-91 / 22-48
phrog_7344 terminase small subunit head and packaging 95.2 0.00095 51-90 / 7-46
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 95.2 0.0011 65-97 / 13-45
phrog_7676 no annotation unknown function 94.3 0.0037 67-92 / 13-38
phrog_769 transcriptional repressor transcription regulation 93.6 0.0081 65-93 / 20-48
phrog_7783 no annotation unknown function 91.2 0.038 53-92 / 137-176
phrog_7950 transcriptional repressor transcription regulation 92.1 0.024 53-88 / 7-40
phrog_836 late transcriptional activator transcription regulation 93.5 0.0088 61-96 / 93-135
phrog_8 transcriptional regulator transcription regulation 93.6 0.0078 67-93 / 11-36
phrog_925 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.6 0.031 53-92 / 2-39
phrog_9586 no annotation unknown function 94.4 0.0036 61-94 / 264-297
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 92.3 0.021 63-93 / 12-41

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF09862.8 Protein of unknown function (DUF2089) 8.2E-11 40-118 / 1-75
PF14690.5 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 6.1E-07 15-58 / 3-47
PF03811.12 InsA N-terminal domain 7.7E-07 14-59 / 5-35
PF00872.17 Transposase, Mutator family 1.8E-06 14-118 / 44-142
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 4.9E-06 92-116 / 82-106
PF06782.10 Uncharacterised protein family (UPF0236) 1.5E-05 49-118 / 89-165
PF04216.11 Protein involved in formate dehydrogenase formation 1.7E-05 14-60 / 172-217
PF12759.6 InsA C-terminal domain 2.5E-05 84-116 / 13-45
PF07750.10 GcrA cell cycle regulator 3.5E-05 79-119 / 5-46
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 7.4E-05 90-122 / 11-43
PF00292.17 'Paired box' domain 7.9E-05 76-119 / 17-60
PF04606.11 Ogr/Delta-like zinc finger 9.4E-05 50-62 / 23-37
PF09607.9 Brinker DNA-binding domain 0.00013 80-119 / 9-52
PF15978.4 Tn7-like transposition protein D 0.00014 81-119 / 191-230
PF08822.10 Protein of unknown function (DUF1804) 0.00015 82-120 / 8-47
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.00016 85-116 / 20-50
PF07141.10 Putative bacteriophage terminase small subunit 0.00024 84-118 / 23-57
PF01710.15 Transposase 0.00026 83-118 / 9-44
PF05344.10 Domain of Unknown Function (DUF746) 0.00033 91-120 / 11-40
PF10654.8 Protein of unknown function (DUF2481) 0.00041 89-119 / 77-107
PF10668.8 Phage terminase small subunit 0.00051 92-121 / 22-51
PF13011.5 leucine-zipper of insertion element IS481 0.00054 90-120 / 22-52
PF06627.10 Protein of unknown function (DUF1153) 0.00057 82-124 / 35-78
PF02796.14 Helix-turn-helix domain of resolvase 0.00061 91-115 / 20-44
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.00059 85-120 / 48-83
PF11427.7 Tc3 transposase 0.00064 91-119 / 19-47
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 0.00077 91-120 / 18-47
PF13936.5 Helix-turn-helix domain 0.00084 90-114 / 18-42
PF05331.10 Protein of unknown function (DUF742) 0.00086 91-121 / 52-82
PF08765.10 Mor transcription activator family 0.00088 91-120 / 71-100
PF04218.12 CENP-B N-terminal DNA-binding domain 0.00091 93-118 / 24-49
PF13518.5 Helix-turn-helix domain 0.0011 91-123 / 10-42
PF03604.12 DNA directed RNA polymerase, 7 kDa subunit 0.0011 16-45 / 2-25
PF06322.10 Phage NinH protein 0.0012 92-121 / 16-45
PF07638.10 ECF sigma factor 0.0012 89-119 / 146-176
PF04936.11 Protein of unknown function (DUF658) 0.0015 92-118 / 14-40
PF14493.5 Helix-turn-helix domain 0.0015 90-120 / 10-40
PF02701.14 Dof domain, zinc finger 0.0018 49-62 / 25-38
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.002 76-117 / 88-132
PF16087.4 Domain of unknown function (DUF4817) 0.0022 91-120 / 15-52
PF13453.5 Transcription factor zinc-finger 0.0023 50-62 / 17-29
PF08535.9 KorB domain 0.0026 92-119 / 3-30
PF16677.4 DNA-packaging protein gp3 0.0026 91-116 / 28-53
PF04552.12 Sigma-54, DNA binding domain 0.0027 90-118 / 46-74
PF02954.18 Bacterial regulatory protein, Fis family 0.0029 92-115 / 16-39
PF17443.1 Uncharacterized protein pXO2-72 0.0029 92-114 / 8-30
PF01527.19 Transposase 0.003 91-117 / 20-46
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0033 92-121 / 23-52
PF07453.12 NUMOD1 domain 0.0034 93-112 / 20-39
PF13412.5 Winged helix-turn-helix DNA-binding 0.0035 92-120 / 17-45
PF02042.14 RWP-RK domain 0.0036 92-121 / 12-41
PF00356.20 Bacterial regulatory proteins, lacI family 0.0041 94-116 / 1-23
PF00376.22 MerR family regulatory protein 0.0043 95-116 / 2-23
PF01381.21 Helix-turn-helix 0.0044 91-116 / 8-33
PF08281.11 Sigma-70, region 4 0.0045 90-117 / 24-51
PF13384.5 Homeodomain-like domain 0.0047 91-116 / 16-41
PF11242.7 Protein of unknown function (DUF2774) 0.0048 90-120 / 12-42
PF13411.5 MerR HTH family regulatory protein 0.0053 94-117 / 2-25
PF13556.5 PucR C-terminal helix-turn-helix domain 0.0056 92-120 / 12-40
PF11112.7 Pyocin activator protein PrtN 0.0057 92-117 / 13-39
PF13551.5 Winged helix-turn helix 0.0058 91-121 / 10-40
PF01371.18 Trp repressor protein 0.0058 89-120 / 45-76
PF05225.15 helix-turn-helix, Psq domain 0.006 92-117 / 16-42
PF13309.5 HTH domain 0.0063 93-114 / 42-63
PF16509.4 TrfB plasmid transcriptional repressor 0.0071 91-118 / 30-57
PF04545.15 Sigma-70, region 4 0.0071 91-117 / 23-49
PF10975.7 Protein of unknown function (DUF2802) 0.0073 81-114 / 32-65
PF06806.11 Putative excisionase (DUF1233) 0.0074 93-114 / 10-31
PF00325.19 Bacterial regulatory proteins, crp family 0.0083 94-118 / 4-28
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.0083 93-114 / 4-25
PF08004.10 Protein of unknown function (DUF1699) 0.008 78-113 / 90-129
PF14354.5 Restriction alleviation protein Lar 0.0082 15-25 / 4-14
PF13413.5 Helix-turn-helix domain 0.0087 91-116 / 8-33
PF13404.5 AsnC-type helix-turn-helix domain 0.009 92-116 / 17-41

Annotations of the NCBI proteins of this PHROG


1:transposase 1:DNA binding domain protein 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0019069 viral capsid assembly
GO:0006352 DNA-templated transcription, initiation
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0004803 transposase activity
GO:0043565 sequence-specific DNA binding
GO:0005524 ATP binding
GO:0016987 sigma factor activity
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005667 transcription factor complex
GO:0006351 transcription, DNA-templated
GO:0005622 intracellular
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0003700 DNA binding transcription factor activity
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity

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