phrog_20891 is made of 4 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
215.5 261 237


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_022069_p29 YP_008410701.1 HNH endonuclease domain NC_022069 Mycobacterium phage Jabbawokkie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023738_p148 YP_009018159.1 gp148 NC_023738 Mycobacterium phage Thibault Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
MF347639_p42 AST15274.1 helix-turn-helix DNA binding domain protein MF347639 Streptomyces phage Samisti12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Samisti12.
MF347637_p38 ASR77529.1 HNH endonuclease MF347637 Streptomyces phage Paradiddles Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Paradiddles.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1493 101 endolysin lysis 2 4.80E-11 1.44

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10730 HNH endonuclease DNA, RNA and nucleotide metabolism 99.2 2.1E-15 116-185 / 10-78
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 5E-05 22-182 / 44-189
phrog_14913 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 2.6E-08 123-185 / 14-82
phrog_1492 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00039 123-181 / 54-108
phrog_15471 HNH endonuclease DNA, RNA and nucleotide metabolism 98.1 3.7E-09 120-184 / 12-72
phrog_1891 HNH endonuclease DNA, RNA and nucleotide metabolism 94.9 0.0018 120-185 / 102-162
phrog_19902 HNH endonuclease DNA, RNA and nucleotide metabolism 98.8 1.6E-12 79-182 / 10-126
phrog_21964 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 8.1E-07 140-184 / 4-48
phrog_25114 no annotation unknown function 99.0 2.8E-13 103-181 / 43-121
phrog_59 HNH endonuclease DNA, RNA and nucleotide metabolism 97.6 1.5E-07 122-181 / 37-90
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 98.6 2E-11 118-184 / 59-125
phrog_826 HNH endonuclease DNA, RNA and nucleotide metabolism 93.4 0.0097 122-181 / 31-86
phrog_959 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.6E-06 120-185 / 37-95
phrog_99 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2.2E-05 123-183 / 39-89

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05551.10 Zinc-binding loop region of homing endonuclease 1.4E-08 133-212 / 2-81
PF13392.5 HNH endonuclease 1.7E-07 163-207 / 2-44
PF05766.11 Bacteriophage Lambda NinG protein 0.0001 161-210 / 80-134
PF10013.8 Uncharacterized protein conserved in bacteria (DUF2256) 0.0067 33-73 / 6-39

Annotations of the NCBI proteins of this PHROG


1:hypothetical protein 1:helix-turn-helix DNA binding domain protein 1:HNH endonuclease domain 1:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
no GO term               

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