phrog_21388 is made of 4 protein sequences and is annotated as "exonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
129.25 147 147


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KX532239_p86 APC42951.1 exonuclease KX532239 Staphylococcus phage StAP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Twortvirinae; Silviavirus; unclassified Silviavirus.
KY779848_p131 ARQ95887.1 exonuclease KY779848 Staphylococcus phage qdsa001 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Twortvirinae; Silviavirus; unclassified Silviavirus.
DQ004855_p46 AAY53349.1 gp46 DQ004855 Listeria virus P100 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Jasinkavirinae; Pecentumvirus.
p386993 no NCBI prot ID no annotation VI_06738 Gammaproteobacteria_gi_484016469 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2773 51 no annotation unknown function 2 6.00E-12 2.34

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10445 no annotation unknown function 96.7 1.2E-05 2-94 / 3-92
phrog_1499 no annotation unknown function 98.3 9.5E-10 1-100 / 2-85
phrog_19980 no annotation unknown function 97.6 1.3E-07 2-99 / 1-95
phrog_25363 no annotation unknown function 95.5 0.00057 2-66 / 5-59
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 94.4 0.0036 12-58 / 25-62
phrog_3940 no annotation unknown function 93.2 0.011 3-58 / 7-52
phrog_4747 no annotation unknown function 96.2 9.9E-05 2-86 / 3-74
phrog_7507 no annotation unknown function 94.8 0.002 2-60 / 1-49
phrog_77 SbcC-like subunit of palindrome specific endonuclease DNA, RNA and nucleotide metabolism 99.9 3.1E-26 1-106 / 1-99
phrog_800 terminase small subunit head and packaging 92.8 0.015 25-58 / 8-32
phrog_8323 no annotation unknown function 96.5 2.8E-05 2-68 / 27-83
phrog_9802 no annotation unknown function 92.9 0.014 4-73 / 5-64

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13476.5 AAA domain 7.5E-13 6-62 / 1-48
PF13514.5 AAA domain 3E-11 2-62 / 1-54
PF13175.5 AAA ATPase domain 2.6E-10 2-59 / 1-47
PF02463.18 RecF/RecN/SMC N terminal domain 4.7E-10 3-62 / 1-52
PF11398.7 Protein of unknown function (DUF2813) 2.7E-09 2-60 / 1-48
PF04310.11 MukB N-terminal 7.8E-09 1-60 / 3-52
PF12128.7 Protein of unknown function (DUF3584) 4.3E-07 7-60 / 1-45
PF16813.4 CRISPR-associated protein Csn2 subfamily St 2.1E-06 24-61 / 14-42
PF13304.5 AAA domain, putative AbiEii toxin, Type IV TA system 4E-06 42-57 / 7-22
PF13166.5 AAA domain 1.1E-05 24-59 / 17-43
PF02456.14 Adenovirus IVa2 protein 0.00011 26-58 / 81-106
PF09818.8 Predicted ATPase of the ABC class 0.00039 21-58 / 244-272
PF11602.7 ATPase P4 of dsRNA bacteriophage phi-12 0.00043 24-59 / 121-147
PF00485.17 Phosphoribulokinase / Uridine kinase family 0.0005 41-59 / 6-24
PF00625.20 Guanylate kinase 0.00093 27-58 / 4-26
PF00005.26 ABC transporter 0.0011 21-59 / 7-36
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 0.0013 42-58 / 8-24
PF13521.5 AAA domain 0.0015 41-58 / 6-23
PF03205.13 Molybdopterin guanine dinucleotide synthesis protein B 0.0016 41-59 / 6-24
PF13555.5 P-loop containing region of AAA domain 0.0016 4-58 / 1-46
PF13671.5 AAA domain 0.0016 42-57 / 7-22
PF00350.22 Dynamin family 0.0017 41-58 / 5-22
PF01580.17 FtsK/SpoIIIE family 0.0017 25-58 / 38-62
PF06414.11 Zeta toxin 0.0017 25-58 / 14-38
PF00488.20 MutS domain V 0.0017 40-57 / 4-21
PF02223.16 Thymidylate kinase 0.0018 41-58 / 3-20
PF03266.14 NTPase 0.0019 41-58 / 6-23
PF07931.11 Chloramphenicol phosphotransferase-like protein 0.0019 42-58 / 9-25
PF10649.8 Protein of unknown function (DUF2478) 0.0021 41-59 / 5-23
PF13173.5 AAA domain 0.0024 42-57 / 10-25
PF01926.22 50S ribosome-binding GTPase 0.0027 41-57 / 6-22
PF13191.5 AAA ATPase domain 0.0027 26-58 / 25-48
PF03796.14 DnaB-like helicase C terminal domain 0.0029 24-58 / 18-43
PF00437.19 Type II/IV secretion system protein 0.0029 26-59 / 131-155
PF00265.17 Thymidine kinase 0.0029 27-58 / 3-25
PF01745.15 Isopentenyl transferase 0.003 27-58 / 3-25
PF13238.5 AAA domain 0.003 41-58 / 5-22
PF03976.13 Polyphosphate kinase 2 (PPK2) 0.0031 26-58 / 29-52
PF01121.19 Dephospho-CoA kinase 0.0031 41-58 / 7-24
PF13401.5 AAA domain 0.0032 26-58 / 6-29
PF02492.18 CobW/HypB/UreG, nucleotide-binding domain 0.0032 42-55 / 8-21
PF04665.11 Poxvirus A32 protein 0.0033 25-58 / 13-37
PF13481.5 AAA domain 0.0034 25-58 / 28-52
PF02224.17 Cytidylate kinase 0.0037 40-58 / 4-22
PF01712.18 Deoxynucleoside kinase 0.0041 41-58 / 5-22
PF03668.14 P-loop ATPase protein family 0.0042 42-56 / 9-23
PF05729.11 NACHT domain 0.0042 42-58 / 8-24
PF05272.10 Virulence-associated protein E 0.0043 26-58 / 60-83
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 0.0044 25-58 / 14-38
PF00910.21 RNA helicase 0.0045 41-59 / 5-23
PF10662.8 Ethanolamine utilisation - propanediol utilisation 0.0049 42-56 / 9-23
PF13189.5 Cytidylate kinase-like family 0.005 41-58 / 6-23
PF13207.5 AAA domain 0.0052 41-58 / 2-19
PF00308.17 Bacterial dnaA protein 0.0054 26-58 / 34-57
PF06745.12 KaiC 0.0054 24-58 / 18-43
PF13479.5 AAA domain 0.0055 42-56 / 10-24
PF04275.13 Phosphomevalonate kinase 0.0056 41-58 / 3-20
PF02689.13 Helicase 0.0058 25-58 / 53-77
PF01591.17 6-phosphofructo-2-kinase 0.0059 26-58 / 10-33
PF00071.21 Ras family 0.006 41-57 / 6-22
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 0.006 41-55 / 5-19
PF05621.10 Bacterial TniB protein 0.006 26-58 / 39-62
PF01637.17 ATPase domain predominantly from Archaea 0.007 25-58 / 20-44
PF04851.14 Type III restriction enzyme, res subunit 0.0071 26-58 / 24-47
PF08303.10 tRNA ligase kinase domain 0.0073 42-58 / 7-23
PF03029.16 Conserved hypothetical ATP binding protein 0.0075 41-59 / 3-21
PF08433.9 Chromatin associated protein KTI12 0.0076 42-58 / 9-25
PF00004.28 ATPase family associated with various cellular activities (AAA) 0.0077 41-58 / 5-22
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.0078 26-58 / 5-28
PF04548.15 AIG1 family 0.0082 42-56 / 8-22

Annotations of the NCBI proteins of this PHROG


2:exonuclease 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004161 dimethylallyltranstransferase activity
GO:0006695 cholesterol biosynthetic process
GO:0004673 protein histidine kinase activity
GO:0003972 RNA ligase (ATP) activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0043752 adenosylcobinamide kinase activity
GO:0003677 DNA binding
GO:0019073 viral DNA genome packaging
GO:0004127 cytidylate kinase activity
GO:0006260 DNA replication
GO:0003678 DNA helicase activity
GO:0016787 hydrolase activity
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0003873 6-phosphofructo-2-kinase activity
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0004140 dephospho-CoA kinase activity
GO:0016887 ATPase activity
GO:0000160 phosphorelay signal transduction system
GO:0006576 cellular biogenic amine metabolic process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0009236 cobalamin biosynthetic process
GO:0016020 membrane
GO:0006139 nucleobase-containing compound metabolic process
GO:0003724 RNA helicase activity
GO:0019072 viral genome packaging
GO:0007059 chromosome segregation
GO:0051188 cofactor biosynthetic process
GO:0015937 coenzyme A biosynthetic process
GO:0005737 cytoplasm
GO:0016740 transferase activity
GO:0000166 nucleotide binding
GO:0006000 fructose metabolic process
GO:0009295 nucleoid
GO:0004797 thymidine kinase activity
GO:0005525 GTP binding
GO:0004631 phosphomevalonate kinase activity
GO:0004386 helicase activity
GO:0009058 biosynthetic process
GO:0000155 phosphorelay sensor kinase activity
GO:0030983 mismatched DNA binding
GO:0003924 GTPase activity
GO:0005524 ATP binding
GO:0003723 RNA binding
GO:0016301 kinase activity
GO:0008152 metabolic process
GO:0006298 mismatch repair
GO:0030261 chromosome condensation

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