phrog_21636 is made of 4 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
61.25 65 61


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p368209 no NCBI prot ID no annotation VI_00019 Actinobacteria_gi_545410648 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p413926 no NCBI prot ID no annotation VI_00024 Actinobacteria_gi_319434515 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p427735 no NCBI prot ID no annotation VI_04174 Actinobacteria_gi_548569677 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p204985 no NCBI prot ID no annotation VI_00022 Actinobacteria_gi_223955933_488_36693 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_8013 14 no annotation unknown function 3 2.56E-18 8.71
phrog_25066 3 no annotation unknown function 3 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_16815 no annotation unknown function 93.1 0.012 6-34 / 32-60

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF07638.10 ECF sigma factor 2.4E-09 3-48 / 134-179
PF03333.12 Adhesin biosynthesis transcription regulatory protein 9.8E-09 4-48 / 41-85
PF05331.10 Protein of unknown function (DUF742) 1.4E-08 3-45 / 39-80
PF07750.10 GcrA cell cycle regulator 1.6E-08 3-43 / 3-44
PF12759.6 InsA C-terminal domain 4.8E-08 4-41 / 7-44
PF08822.10 Protein of unknown function (DUF1804) 6.9E-08 2-43 / 2-44
PF01710.15 Transposase 9.5E-08 2-43 / 2-43
PF06530.11 Phage antitermination protein Q 1.3E-07 4-49 / 65-110
PF00292.17 'Paired box' domain 1.4E-07 4-43 / 19-58
PF07141.10 Putative bacteriophage terminase small subunit 1.7E-07 8-44 / 21-57
PF09607.9 Brinker DNA-binding domain 2.7E-07 4-43 / 7-50
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 3.2E-07 10-44 / 5-39
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 3.6E-07 4-47 / 4-48
PF07374.10 Protein of unknown function (DUF1492) 3.8E-07 5-45 / 58-98
PF04545.15 Sigma-70, region 4 4E-07 3-45 / 5-51
PF10654.8 Protein of unknown function (DUF2481) 7.7E-07 13-48 / 75-110
PF04218.12 CENP-B N-terminal DNA-binding domain 9E-07 10-45 / 14-50
PF08281.11 Sigma-70, region 4 9.1E-07 9-43 / 17-51
PF05344.10 Domain of Unknown Function (DUF746) 8.9E-07 15-46 / 9-40
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 8.9E-07 4-47 / 19-62
PF13936.5 Helix-turn-helix domain 1.1E-06 6-40 / 8-42
PF02001.15 Protein of unknown function DUF134 1.1E-06 6-49 / 35-78
PF16509.4 TrfB plasmid transcriptional repressor 1.2E-06 6-46 / 19-59
PF13542.5 Helix-turn-helix domain of transposase family ISL3 1.3E-06 8-42 / 17-50
PF02796.14 Helix-turn-helix domain of resolvase 1.4E-06 10-40 / 13-43
PF10668.8 Phage terminase small subunit 1.9E-06 7-44 / 8-48
PF13011.5 leucine-zipper of insertion element IS481 1.9E-06 6-44 / 11-50
PF04552.12 Sigma-54, DNA binding domain 2.7E-06 15-43 / 45-73
PF04936.11 Protein of unknown function (DUF658) 0.00032 17-43 / 87-113
PF10975.7 Protein of unknown function (DUF2802) 3.5E-06 7-39 / 32-64
PF16264.4 SatD family (SatD) 3.6E-06 4-48 / 152-201
PF11427.7 Tc3 transposase 4E-06 8-43 / 10-45
PF06322.10 Phage NinH protein 4.8E-06 17-45 / 15-43
PF12824.6 Mitochondrial ribosomal protein subunit L20 5.5E-06 3-43 / 89-132
PF14493.5 Helix-turn-helix domain 8.6E-06 14-43 / 8-37
PF13384.5 Homeodomain-like domain 9.1E-06 8-42 / 7-41
PF00196.18 Bacterial regulatory proteins, luxR family 9.2E-06 13-49 / 12-48
PF08765.10 Mor transcription activator family 8.8E-06 17-45 / 71-99
PF11242.7 Protein of unknown function (DUF2774) 9.7E-06 14-46 / 10-42
PF16677.4 DNA-packaging protein gp3 1.2E-05 17-42 / 28-53
PF05225.15 helix-turn-helix, Psq domain 1.2E-05 16-43 / 14-42
PF04967.11 HTH DNA binding domain 1.3E-05 19-45 / 24-50
PF01527.19 Transposase 1.4E-05 6-43 / 8-46
PF13309.5 HTH domain 1.4E-05 19-39 / 42-62
PF06627.10 Protein of unknown function (DUF1153) 1.4E-05 8-44 / 35-72
PF13518.5 Helix-turn-helix domain 1.5E-05 12-44 / 6-37
PF01371.18 Trp repressor protein 1.7E-05 14-44 / 44-74
PF15978.4 Tn7-like transposition protein D 2E-05 10-43 / 194-228
PF13412.5 Winged helix-turn-helix DNA-binding 2.4E-05 17-43 / 16-42
PF17443.1 Uncharacterized protein pXO2-72 2.5E-05 17-41 / 7-31
PF09862.8 Protein of unknown function (DUF2089) 3.1E-05 11-46 / 42-77
PF02954.18 Bacterial regulatory protein, Fis family 3.5E-05 17-41 / 15-39
PF08535.9 KorB domain 4.3E-05 17-43 / 2-28
PF13411.5 MerR HTH family regulatory protein 5.1E-05 20-43 / 2-25
PF13404.5 AsnC-type helix-turn-helix domain 5.4E-05 17-41 / 16-40
PF13556.5 PucR C-terminal helix-turn-helix domain 5.3E-05 16-46 / 10-40
PF01381.21 Helix-turn-helix 5.6E-05 16-41 / 7-32
PF13551.5 Winged helix-turn helix 7.4E-05 15-44 / 8-37
PF06413.10 Neugrin 6.8E-05 3-41 / 11-52
PF08004.10 Protein of unknown function (DUF1699) 6.9E-05 8-39 / 94-129
PF07453.12 NUMOD1 domain 7.8E-05 19-38 / 20-39
PF13591.5 MerR HTH family regulatory protein 8.6E-05 20-41 / 2-23
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 8.8E-05 16-45 / 9-38
PF06806.11 Putative excisionase (DUF1233) 9.2E-05 19-40 / 10-31
PF00376.22 MerR family regulatory protein 0.0001 21-42 / 2-23
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.00011 19-40 / 4-25
PF00356.20 Bacterial regulatory proteins, lacI family 0.00011 20-42 / 1-23
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.00014 20-41 / 53-74
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.00014 17-43 / 22-48
PF07278.10 Protein of unknown function (DUF1441) 0.00015 19-43 / 2-26
PF13022.5 Helix-turn-helix of insertion element transposase 0.00016 18-41 / 25-48
PF13413.5 Helix-turn-helix domain 0.00017 16-42 / 7-33
PF12802.6 MarR family 0.00018 19-44 / 22-47
PF04492.12 Bacteriophage replication protein O 0.00024 18-44 / 49-75
PF10743.8 Regulatory phage protein cox 0.00025 17-42 / 10-35
PF09035.9 Excisionase from transposon Tn916 0.00027 17-40 / 14-37
PF07037.10 Putative transcription regulator (DUF1323) 0.00029 20-41 / 2-23
PF08280.10 M protein trans-acting positive regulator (MGA) HTH domain 0.00029 18-47 / 20-49
PF08222.10 CodY helix-turn-helix domain 0.00032 18-44 / 4-30
PF02042.14 RWP-RK domain 0.00034 16-42 / 10-36
PF01418.16 Helix-turn-helix domain, rpiR family 0.00034 18-43 / 34-59
PF12728.6 Helix-turn-helix domain 0.00036 19-41 / 2-25
PF12116.7 Stage III sporulation protein D 0.00037 17-42 / 18-43
PF07506.10 RepB plasmid partitioning protein 0.00037 14-42 / 17-45
PF00325.19 Bacterial regulatory proteins, crp family 0.00043 19-42 / 3-26
PF06971.12 Putative DNA-binding protein N-terminus 0.00044 18-39 / 27-48
PF16221.4 winged helix-turn-helix 0.00051 18-44 / 46-72
PF05043.12 Mga helix-turn-helix domain 0.00052 18-46 / 30-58
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 0.00051 19-43 / 23-47
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 0.00053 16-42 / 21-47
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00058 17-43 / 17-43
PF07471.11 Phage DNA packaging protein Nu1 0.00058 19-42 / 3-26
PF01022.19 Bacterial regulatory protein, arsR family 0.00061 18-43 / 16-41
PF12964.6 Protein of unknown function (DUF3853) 0.00067 18-43 / 45-70
PF05584.10 Sulfolobus plasmid regulatory protein 0.00071 16-44 / 16-44
PF13725.5 Possible tRNA binding domain 0.00078 4-46 / 101-143
PF08279.11 HTH domain 0.00092 17-45 / 14-42
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.00097 17-40 / 23-46
PF09012.9 FeoC like transcriptional regulator 0.0011 18-44 / 14-40
PF00440.22 Bacterial regulatory proteins, tetR family 0.0011 19-42 / 16-39
PF06576.10 Protein of unknown function (DUF1133) 0.0011 8-43 / 121-165
PF09182.9 Bacterial purine repressor, N-terminal 0.0012 17-44 / 19-46
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.0015 17-41 / 9-34
PF09824.8 ArsR transcriptional regulator 0.0016 5-43 / 16-53
PF12298.7 Eukaryotic mitochondrial regulator protein 0.0021 3-39 / 17-54
PF09339.9 IclR helix-turn-helix domain 0.0025 19-43 / 19-43
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0023 16-41 / 124-149
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.0025 17-43 / 26-52
PF05339.10 Protein of unknown function (DUF739) 0.0025 17-41 / 15-39
PF14549.5 DNA-binding transcriptional regulator Cro 0.0025 17-38 / 9-29
PF13744.5 Helix-turn-helix domain 0.0026 17-41 / 30-54
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.0029 17-43 / 21-47
PF04182.11 B-block binding subunit of TFIIIC 0.0032 18-44 / 18-44
PF09048.9 Cro 0.0033 16-42 / 11-37
PF07900.10 Protein of unknown function (DUF1670) 0.0033 17-44 / 94-121
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.004 18-41 / 11-35
PF12844.6 Helix-turn-helix domain 0.0041 17-41 / 11-35
PF00392.20 Bacterial regulatory proteins, gntR family 0.0043 18-43 / 23-49
PF13463.5 Winged helix DNA-binding domain 0.0044 18-43 / 17-42
PF02082.19 Transcriptional regulator 0.0046 19-43 / 25-49
PF13601.5 Winged helix DNA-binding domain 0.0048 18-43 / 14-39
PF15977.4 Winged helix-turn-helix DNA binding 0.0048 18-43 / 23-48
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.0058 20-39 / 10-29
PF09904.8 Winged helix-turn helix 0.0061 18-43 / 21-46
PF09202.10 Rio2, N-terminal 0.0064 18-43 / 24-49
PF01047.21 MarR family 0.0071 18-43 / 17-42
PF07618.10 Protein of unknown function (DUF1580) 0.0068 24-42 / 8-26
PF14947.5 Winged helix-turn-helix 0.0072 17-43 / 15-41
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0074 18-43 / 21-46
PF11994.7 Protein of unknown function (DUF3489) 0.0068 10-45 / 11-48
PF11972.7 HTH DNA binding domain 0.0074 18-42 / 13-37
PF13171.5 Protein of unknown function (DUF4004) 0.0074 20-42 / 4-26
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0082 17-43 / 16-42
PF04703.11 FaeA-like protein 0.0085 17-43 / 13-39
PF05269.10 Bacteriophage CII protein 0.0088 17-41 / 22-46

Annotations of the NCBI proteins of this PHROG


no RefSeq proteins in this PHROG (only proteins from VirSorter contigs)

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0043565 sequence-specific DNA binding
GO:0004803 transposase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0019069 viral capsid assembly
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0006352 DNA-templated transcription, initiation
GO:0051775 response to redox state
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0003700 DNA binding transcription factor activity
GO:0000150 recombinase activity
GO:0006313 transposition, DNA-mediated
GO:0016987 sigma factor activity
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0009289 pilus
GO:0006260 DNA replication
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0004674 protein serine/threonine kinase activity

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