phrog_2190 is made of 69 protein sequences and is annotated as "replication initiation protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
192.52 265 198


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_028782_p27 YP_009197496.1 plasmid replication-relaxation protein NC_028782 Bacillus phage Pavlov Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus; unclassified Pagevirus.
NC_029069_p89 YP_009223239.1 replication-relaxation protein NC_029069 Bacillus phage BM5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_022764_p27 YP_008770534.1 plasmid replication/relaxation protein NC_022764 Bacillus phage Page Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_029069_p30 YP_009223180.1 replication-relaxation protein NC_029069 Bacillus phage BM5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_022770_p27 YP_008771345.1 plasmid replication-relaxation protein NC_022770 Bacillus phage Pony Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_027394_p27 YP_009152826.1 plasmid replication/relaxation protein NC_027394 Bacillus phage Pookie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_028926_p28 YP_009210063.1 replication-relaxation protein NC_028926 Bacillus phage Palmer Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_027372_p26 YP_009151494.1 plasmid replication-relaxation protein NC_027372 Bacillus phage Pascal Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
p188670 no NCBI prot ID no annotation VI_00904 Bacilli_gi_484000434 Viruses.
p48585 no NCBI prot ID no annotation VI_05296 Bacilli_gi_544020570 Viruses; unclassified bacterial viruses.
p199558 no NCBI prot ID no annotation VI_00830 Bacilli_gi_384177910_4724782_4761462 Viruses.
p408110 no NCBI prot ID no annotation VI_00693 Bacilli_gi_507028065_43024_56217 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p133524 no NCBI prot ID no annotation VI_00979 Bacilli_gi_402558824_1373424_1415725 Viruses.
NC_022766_p66 YP_008770702.1 plasmid relaxation/replication protein NC_022766 Bacillus virus Glittering Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Andromedavirus.
p151919 no NCBI prot ID no annotation VI_00432 Bacilli_gi_423560596_4340049_4380676 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_030904_p34 YP_009273358.1 hypothetical protein NC_030904 Bacillus phage vB_BhaS-171 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_020478_p68 YP_007517533.1 hypothetical protein NC_020478 Bacillus virus Andromeda Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Andromedavirus.
p18173 no NCBI prot ID no annotation VI_00421 Bacilli_gi_423480041 Viruses.
NC_020883_p84 YP_007678110.1 hypothetical protein NC_020883 Bacillus phage PM1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Saundersvirus; unclassified Saundersvirus.
NC_022773_p70 YP_008771893.1 plasmid replication-relaxation protein NC_022773 Bacillus virus Blastoid Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Andromedavirus.
NC_022765_p67 YP_008770624.1 plasmid replication-relaxation protein NC_022765 Bacillus virus Riggi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Andromedavirus.
p58709 no NCBI prot ID no annotation VI_00423 Bacilli_gi_423490981 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_009737_p41 YP_001425620.2 hypothetical protein NC_009737 Bacillus virus 1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Svunavirus.
p383098 no NCBI prot ID no annotation VI_00426 Bacilli_gi_423508375 Viruses.
p152289 no NCBI prot ID no annotation VI_00860 Bacilli_gi_434373506_3817766_3858377 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p35873 no NCBI prot ID no annotation VI_00416 Bacilli_gi_423422311_2192763_2255576 Viruses.
NC_020479_p66 YP_007517610.1 replication/relaxation protein NC_020479 Bacillus virus Curly Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Andromedavirus.
p152619 no NCBI prot ID no annotation VI_00859 Bacilli_gi_434373506_3050122_3090701 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KT001912_p34 AKU43372.1 plasmid replication-relaxation protein KT001912 Bacillus phage Silence Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p55812 no NCBI prot ID no annotation VI_00713 Bacilli_gi_507065719 Viruses.
p27680 no NCBI prot ID no annotation VI_00414 Bacilli_gi_423416314 Viruses.
p20786 no NCBI prot ID no annotation VI_00466 Bacilli_gi_365164259 Viruses; unclassified bacterial viruses.
p62783 no NCBI prot ID no annotation VI_00686 Bacilli_gi_507025306_845403_896624 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_004820_p74 NP_852554.1 hypothetical protein NC_004820 Bacillus phage phBC6A51 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p193371 no NCBI prot ID no annotation VI_00879 Bacilli_gi_507027716 Viruses.
p31652 no NCBI prot ID no annotation VI_00417 Bacilli_gi_423427972 Viruses.
p23714 no NCBI prot ID no annotation VI_00418 Bacilli_gi_423433709 Viruses.
NC_019502_p50 YP_007004381.1 phage protein NC_019502 Bacillus phage phIS3501 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_020477_p66 YP_007517456.1 replication/relaxation protein NC_020477 Bacillus virus Eoghan Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Andromedavirus.
KC330682_p66 AGE60984.1 replication/relaxation protein KC330682 Bacillus virus Taylor Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Andromedavirus.
KU836751_p65 AMR60103.1 replication/relaxation protein KU836751 Bacillus phage Leo2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Andromedavirus; unclassified Andromedavirus.
p152445 no NCBI prot ID no annotation VI_00436 Bacilli_gi_423584588_368833_409419 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
DQ222855_p23 ABA46486.1 conserved phage protein DQ222855 Bacillus phage Gamma Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
p300105 no NCBI prot ID no annotation VI_00451 Bacilli_gi_238801502_3570308_3596189 Viruses.
DQ289556_p23 ABC40475.1 conserved phage protein DQ289556 Bacillus phage Gamma isolate d'Herelle Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
NC_007814_p22 YP_512332.1 hypothetical protein NC_007814 Bacillus phage Fah Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
NC_007458_p23 YP_338206.1 conserved phage protein NC_007458 Bacillus phage Gamma Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
NC_007734_p23 YP_459987.1 conserved phage protein NC_007734 Bacillus virus Wbeta Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus.
KY963371_p25 ARW58534.1 hypothetical protein KY963371 Bacillus phage Carmel_SA Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
p291458 no NCBI prot ID no annotation VI_00403 Bacilli_gi_238801476_3248097_3274994 Viruses.
KY963370_p24 ARW58477.1 hypothetical protein KY963370 Bacillus phage Negev_SA Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
KY963369_p27 ARW58416.1 hypothetical protein KY963369 Bacillus phage Tavor_SA Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
p108594 no NCBI prot ID no annotation VI_00689 Bacilli_gi_507027221_2388773_2433538 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p79416 no NCBI prot ID no annotation VI_04404 Bacilli_gi_196042459_4851_52747 Viruses.
p150373 no NCBI prot ID no annotation VI_00419 Bacilli_gi_423445290 Viruses.
NC_018277_p28 YP_006560716.1 DNA-binding protein containing HTH domain NC_018277 Staphylococcus phage SpaA1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p380970 no NCBI prot ID no annotation VI_00043 Actinobacteria_gi_483996828 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_031055_p29 YP_009285273.1 hypothetical protein NC_031055 Bacillus phage PfEFR-5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KT967075_p25 ALN97383.1 hypothetical protein KT967075 Bacillus phage phi4I1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_023599_p27 YP_009009171.1 hypothetical protein NC_023599 Bacillus phage phiCM3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p74602 no NCBI prot ID no annotation VI_00703 Bacilli_gi_507048098 Viruses.
NC_018085_p23 YP_006488693.1 hypothetical protein NC_018085 Bacillus phage BtCS33 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p36285 no NCBI prot ID no annotation VI_00427 Bacilli_gi_423532033 Viruses.
p17517 no NCBI prot ID no annotation VI_00712 Bacilli_gi_507057479 Viruses.
NC_008376_p43 YP_764499.2 hypothetical protein NC_008376 Geobacillus phage GBSV1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Svunavirus.
p61156 no NCBI prot ID no annotation VI_00415 Bacilli_gi_423416397 Viruses.
p58332 no NCBI prot ID no annotation VI_00732 Bacilli_gi_163937941 Viruses.
p54784 no NCBI prot ID no annotation VI_00409 Bacilli_gi_423388038 Viruses.
p16211 no NCBI prot ID no annotation VI_00865 Bacilli_gi_514961984 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1358 109 FtsK/SpoIIIE-like protein moron, auxiliary metabolic gene and host takeover 68 1.24E-254 245.03
phrog_5422 24 no annotation unknown function 15 3.06E-58 48.64
phrog_25515 3 no annotation unknown function 3 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_22495 replication initiation protein DNA, RNA and nucleotide metabolism 100.0 2.2E-37 84-198 / 1-113
phrog_9381 replication initiation by nicking DNA, RNA and nucleotide metabolism 98.8 4.9E-12 2-182 / 30-253
phrog_9996 no annotation unknown function 95.1 0.0013 2-174 / 4-172

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13814.5 Replication-relaxation 3.1E-18 21-176 / 1-158
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 4.6E-05 11-80 / 4-91
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.00014 10-79 / 4-88
PF04079.15 Segregation and condensation complex subunit ScpB 0.00016 10-80 / 78-150
PF09114.9 Transcription factor MotA, activation domain 0.00033 10-81 / 11-80
PF13463.5 Winged helix DNA-binding domain 0.00037 14-74 / 2-66
PF14277.5 Domain of unknown function (DUF4364) 0.00065 18-80 / 3-71
PF01090.18 Ribosomal protein S19e 0.0011 16-81 / 52-134
PF09202.10 Rio2, N-terminal 0.0012 12-80 / 3-75
PF13601.5 Winged helix DNA-binding domain 0.0014 18-80 / 3-70
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.0015 11-62 / 4-56
PF14947.5 Winged helix-turn-helix 0.0025 17-80 / 4-69
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.0032 11-61 / 4-55
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.0048 13-80 / 2-75
PF01638.16 HxlR-like helix-turn-helix 0.0049 15-80 / 5-75
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.0066 13-57 / 11-54
PF02002.16 TFIIE alpha subunit 0.0066 16-78 / 13-80
PF02295.16 Adenosine deaminase z-alpha domain 0.0076 14-61 / 3-52
PF06163.10 Bacterial protein of unknown function (DUF977) 0.008 11-61 / 8-59

Annotations of the NCBI proteins of this PHROG


18:hypothetical protein 6:plasmid replication-relaxation protein 4:replication/relaxation protein 3:replication-relaxation protein 2:plasmid replication/relaxation protein 1:protein of an unannotated phage 1:plasmid relaxation/replication protein 1:DNA-binding protein containing HTH domain

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006412 translation
GO:0051304 chromosome separation
GO:0006355 regulation of transcription, DNA-templated
GO:0004674 protein serine/threonine kinase activity
GO:0003735 structural constituent of ribosome
GO:0003723 RNA binding
GO:0003677 DNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006468 protein phosphorylation
GO:0005524 ATP binding
GO:0005840 ribosome
GO:0003700 DNA binding transcription factor activity

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