phrog_22048 is made of 3 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
63 67 61


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
FJ174694_p86 ACI12806.1 HNH endonuclease FJ174694 Mycobacterium phage Chah Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bclasvirinae; Pegunavirus; Mycobacterium virus Pg1.
GU247133_p85 ADA83910.1 hypothetical protein GU247133 Mycobacterium phage Fang Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bclasvirinae; Pegunavirus; Mycobacterium virus Soto.
KX443696_p71 ANZ52365.1 HNH endonuclease KX443696 Mycobacterium phage Laurie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bclasvirinae; Rosebushvirus; Mycobacterium virus Godines.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1734 87 no annotation unknown function 2 1.74E-11 1.88

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 96.1 0.00014 2-51 / 103-156
phrog_10696 HNH endonuclease DNA, RNA and nucleotide metabolism 97.7 7.3E-08 3-58 / 38-94
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 91.0 0.043 13-45 / 76-110
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00034 2-48 / 18-74
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 95.6 0.00043 3-48 / 38-80
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 90.9 0.045 3-45 / 31-70
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.3E-05 2-51 / 30-86
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 7.4E-07 3-58 / 26-81
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 95.9 0.0002 3-52 / 53-103
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 92.5 0.018 3-48 / 8-54
phrog_7030 HNH endonuclease DNA, RNA and nucleotide metabolism 95.0 0.0016 2-51 / 28-78
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00011 3-58 / 113-165
phrog_9508 HNH endonuclease DNA, RNA and nucleotide metabolism 91.7 0.03 2-50 / 22-76
phrog_960 HNH endonuclease DNA, RNA and nucleotide metabolism 100.0 1.4E-34 2-60 / 41-99

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13395.5 HNH endonuclease 1E-12 3-48 / 1-51
PF01844.22 HNH endonuclease 4.3E-12 3-46 / 1-46
PF14279.5 HNH endonuclease 5.1E-12 3-50 / 1-47
PF05315.10 ICEA Protein 7.2E-11 1-47 / 94-149
PF05766.11 Bacteriophage Lambda NinG protein 7.7E-11 2-49 / 89-137
PF13391.5 HNH endonuclease 2.3E-10 3-49 / 1-46
PF06147.10 Protein of unknown function (DUF968) 2.1E-09 2-48 / 129-174
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 2.1E-09 2-49 / 255-297
PF16784.4 Putative HNHc nuclease 3.8E-07 2-50 / 125-173
PF16786.4 Recombination enhancement, RecA-dependent nuclease 0.00087 2-46 / 16-65

Annotations of the NCBI proteins of this PHROG


2:HNH endonuclease 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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