phrog_22182 is made of 3 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
73.67 76 75


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_028888_p44 YP_009206700.1 hypothetical protein NC_028888 Lactobacillus phage CL1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_007501_p32 YP_358790.1 hypothetical protein NC_007501 Lactobacillus phage Lc-Nu Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_028911_p36 YP_009208872.1 hypothetical protein NC_028911 Lactobacillus phage iLp1308 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_151 641 transposase integration and excision 3 3.82E-12 2.54

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_8794 sigma factor transcription regulation 93.1 0.013 24-46 / 20-42

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01381.21 Helix-turn-helix 8.9E-09 20-71 / 3-52
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 1.4E-08 13-49 / 10-47
PF13744.5 Helix-turn-helix domain 2.9E-08 12-73 / 17-77
PF13413.5 Helix-turn-helix domain 3.7E-08 20-71 / 3-58
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 6.9E-08 18-73 / 3-56
PF05339.10 Protein of unknown function (DUF739) 7.4E-08 16-72 / 6-60
PF14590.5 Domain of unknown function (DUF4447) 1.3E-07 15-71 / 9-66
PF04645.11 Protein of unknown function, DUF603 1.7E-07 12-65 / 6-60
PF12844.6 Helix-turn-helix domain 3.2E-07 19-72 / 5-56
PF13560.5 Helix-turn-helix domain 5E-07 16-70 / 4-57
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 7.2E-07 17-73 / 73-126
PF08965.9 Domain of unknown function (DUF1870) 8.5E-07 16-49 / 4-40
PF08667.9 BetR domain 1.5E-06 15-72 / 7-66
PF13443.5 Cro/C1-type HTH DNA-binding domain 1.5E-06 27-72 / 13-57
PF00356.20 Bacterial regulatory proteins, lacI family 1.5E-06 27-68 / 1-39
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 1.7E-06 27-72 / 10-52
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 1.7E-06 17-68 / 117-166
PF10654.8 Protein of unknown function (DUF2481) 1.9E-06 10-49 / 65-104
PF12116.7 Stage III sporulation protein D 2.8E-06 25-69 / 18-61
PF05269.10 Bacteriophage CII protein 9.3E-06 19-71 / 16-64
PF12824.6 Mitochondrial ribosomal protein subunit L20 1E-05 7-49 / 86-131
PF04552.12 Sigma-54, DNA binding domain 1.1E-05 9-49 / 30-72
PF00157.16 Pou domain - N-terminal to homeobox domain 2.3E-05 15-68 / 9-64
PF13693.5 Winged helix-turn-helix DNA-binding 3E-05 18-70 / 7-54
PF01371.18 Trp repressor protein 4.2E-05 25-64 / 47-84
PF07750.10 GcrA cell cycle regulator 4.7E-05 10-49 / 3-43
PF08822.10 Protein of unknown function (DUF1804) 5.1E-05 10-48 / 3-42
PF14549.5 DNA-binding transcriptional regulator Cro 5.8E-05 27-72 / 11-50
PF04218.12 CENP-B N-terminal DNA-binding domain 5.8E-05 10-49 / 7-47
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 6.8E-05 11-49 / 4-43
PF07141.10 Putative bacteriophage terminase small subunit 8.7E-05 15-49 / 21-55
PF08535.9 KorB domain 9.1E-05 25-49 / 2-27
PF13404.5 AsnC-type helix-turn-helix domain 9.3E-05 17-47 / 8-39
PF12759.6 InsA C-terminal domain 9.7E-05 10-48 / 6-44
PF06413.10 Neugrin 0.0001 5-49 / 6-53
PF06322.10 Phage NinH protein 0.00011 17-49 / 7-40
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.00011 25-49 / 12-37
PF00292.17 'Paired box' domain 0.00013 8-48 / 16-56
PF02954.18 Bacterial regulatory protein, Fis family 0.00013 20-47 / 10-38
PF13011.5 leucine-zipper of insertion element IS481 0.00013 9-49 / 7-48
PF13412.5 Winged helix-turn-helix DNA-binding 0.00014 15-49 / 6-41
PF00376.22 MerR family regulatory protein 0.00014 27-49 / 1-23
PF02376.14 CUT domain 0.00014 15-49 / 9-45
PF10668.8 Phage terminase small subunit 0.00016 9-49 / 4-46
PF02042.14 RWP-RK domain 0.0002 20-49 / 6-36
PF05331.10 Protein of unknown function (DUF742) 0.00021 8-49 / 37-77
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.00022 10-49 / 40-79
PF01710.15 Transposase 0.00023 10-48 / 3-41
PF07506.10 RepB plasmid partitioning protein 0.00031 18-48 / 14-44
PF16677.4 DNA-packaging protein gp3 0.00033 10-49 / 6-53
PF07638.10 ECF sigma factor 0.00034 10-49 / 134-173
PF06892.10 Phage regulatory protein CII (CP76) 0.00039 26-69 / 20-62
PF17443.1 Uncharacterized protein pXO2-72 0.0004 27-49 / 10-32
PF06806.11 Putative excisionase (DUF1233) 0.0004 27-48 / 11-32
PF04936.11 Protein of unknown function (DUF658) 0.00041 26-49 / 14-38
PF05225.15 helix-turn-helix, Psq domain 0.00041 21-49 / 11-41
PF04545.15 Sigma-70, region 4 0.00053 9-49 / 4-48
PF07453.12 NUMOD1 domain 0.00056 27-45 / 21-39
PF02796.14 Helix-turn-helix domain of resolvase 0.00058 25-47 / 20-43
PF13936.5 Helix-turn-helix domain 0.00065 10-47 / 5-42
PF07278.10 Protein of unknown function (DUF1441) 0.00066 27-49 / 3-25
PF04492.12 Bacteriophage replication protein O 0.00067 9-49 / 24-73
PF01418.16 Helix-turn-helix domain, rpiR family 0.0007 8-49 / 12-58
PF13411.5 MerR HTH family regulatory protein 0.00086 27-49 / 2-24
PF16264.4 SatD family (SatD) 0.001 8-49 / 149-195
PF13591.5 MerR HTH family regulatory protein 0.0011 27-49 / 2-24
PF01022.19 Bacterial regulatory protein, arsR family 0.0011 19-48 / 9-39
PF05344.10 Domain of Unknown Function (DUF746) 0.0011 25-49 / 11-36
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.0011 27-47 / 5-25
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0011 25-49 / 22-47
PF08765.10 Mor transcription activator family 0.0011 26-49 / 72-96
PF11112.7 Pyocin activator protein PrtN 0.0012 27-49 / 15-38
PF05584.10 Sulfolobus plasmid regulatory protein 0.0013 9-48 / 3-41
PF06971.12 Putative DNA-binding protein N-terminus 0.0013 26-46 / 27-48
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.0013 10-49 / 11-51
PF15978.4 Tn7-like transposition protein D 0.0014 15-48 / 192-226
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 0.0014 10-49 / 6-46
PF07037.10 Putative transcription regulator (DUF1323) 0.0015 27-48 / 2-23
PF09035.9 Excisionase from transposon Tn916 0.0015 27-47 / 17-37
PF01527.19 Transposase 0.0016 10-49 / 5-45
PF06627.10 Protein of unknown function (DUF1153) 0.0016 9-49 / 29-70
PF00196.18 Bacterial regulatory proteins, luxR family 0.0019 11-49 / 4-41
PF11427.7 Tc3 transposase 0.0019 25-49 / 19-44
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.002 10-47 / 7-46
PF16509.4 TrfB plasmid transcriptional repressor 0.002 9-49 / 15-55
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.0021 27-47 / 53-73
PF13463.5 Winged helix DNA-binding domain 0.0021 13-49 / 4-41
PF13309.5 HTH domain 0.0022 27-46 / 43-62
PF09607.9 Brinker DNA-binding domain 0.0024 27-49 / 27-49
PF01047.21 MarR family 0.0024 16-48 / 7-40
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.0024 9-48 / 11-49
PF08281.11 Sigma-70, region 4 0.0025 9-48 / 10-49
PF05043.12 Mga helix-turn-helix domain 0.0026 18-49 / 22-54
PF08280.10 M protein trans-acting positive regulator (MGA) HTH domain 0.0027 15-49 / 8-44
PF07825.10 Excisionase-like protein 0.0027 27-49 / 4-28
PF10743.8 Regulatory phage protein cox 0.0028 27-49 / 13-35
PF09048.9 Cro 0.0033 26-49 / 13-37
PF13384.5 Homeodomain-like domain 0.0034 26-47 / 17-39
PF16221.4 winged helix-turn-helix 0.0036 13-49 / 32-70
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.0036 10-48 / 6-45
PF00440.22 Bacterial regulatory proteins, tetR family 0.0038 27-49 / 17-39
PF09182.9 Bacterial purine repressor, N-terminal 0.0042 24-49 / 18-44
PF07471.11 Phage DNA packaging protein Nu1 0.0044 27-49 / 4-26
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 0.0045 8-49 / 16-57
PF12964.6 Protein of unknown function (DUF3853) 0.0046 27-49 / 47-69
PF12728.6 Helix-turn-helix domain 0.0046 27-49 / 3-26
PF13022.5 Helix-turn-helix of insertion element transposase 0.0046 26-48 / 25-48
PF11242.7 Protein of unknown function (DUF2774) 0.005 25-49 / 13-38
PF13518.5 Helix-turn-helix domain 0.0051 25-49 / 10-35
PF12793.6 Sugar transport-related sRNA regulator N-term 0.0057 24-48 / 16-41
PF07374.10 Protein of unknown function (DUF1492) 0.0058 8-48 / 53-94
PF09012.9 FeoC like transcriptional regulator 0.0064 27-48 / 16-37
PF13556.5 PucR C-terminal helix-turn-helix domain 0.0065 25-49 / 11-36
PF14493.5 Helix-turn-helix domain 0.0068 25-49 / 11-36
PF06163.10 Bacterial protein of unknown function (DUF977) 0.007 16-48 / 16-49

Annotations of the NCBI proteins of this PHROG


3:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0043565 sequence-specific DNA binding
GO:0004803 transposase activity
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0006352 DNA-templated transcription, initiation
GO:0051775 response to redox state
GO:0019069 viral capsid assembly
GO:0000150 recombinase activity
GO:0006313 transposition, DNA-mediated
GO:0003700 DNA binding transcription factor activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0005622 intracellular
GO:0006260 DNA replication
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0016987 sigma factor activity

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