phrog_22514 is made of 3 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
181.67 215 187


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KT070868_p63 AKQ08629.1 putative HNH endonuclease KT070868 Bacillus phage PBC5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Saundersvirus; unclassified Saundersvirus.
NC_009552_p48 YP_001285849.1 hypothetical protein NC_009552 Geobacillus virus E2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_019544_p36 YP_007010957.1 HNH endonuclease NC_019544 Deep-sea thermophilic phage D6E Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
no colocalized PHROGS                                                                                          

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 92.3 0.021 62-114 / 27-85
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 91.4 0.036 63-114 / 143-203
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 94.5 0.0032 61-112 / 57-114
phrog_15103 no annotation unknown function 93.2 0.011 61-111 / 195-254
phrog_1588 no annotation unknown function 94.6 0.0026 57-128 / 12-85
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 93.7 0.0073 55-122 / 23-90
phrog_2340 endonuclease DNA, RNA and nucleotide metabolism 90.9 0.045 67-112 / 114-153
phrog_32453 HNH endonuclease DNA, RNA and nucleotide metabolism 94.2 0.0046 59-108 / 65-114
phrog_3497 no annotation unknown function 96.9 7.1E-06 66-109 / 26-98
phrog_398 no annotation unknown function 95.2 0.0011 68-111 / 145-192
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 93.7 0.0074 64-113 / 48-101
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 1.6E-13 2-111 / 3-86
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.002 61-115 / 13-73
phrog_7566 no annotation unknown function 95.1 0.0013 64-120 / 7-69
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 92.2 0.023 50-107 / 52-108
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 6.4E-07 47-107 / 8-75
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 95.3 0.00086 54-118 / 98-161

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05315.10 ICEA Protein 1.2E-07 75-136 / 77-150
PF13395.5 HNH endonuclease 4.7E-07 94-135 / 1-50
PF01844.22 HNH endonuclease 1.6E-06 94-134 / 1-46
PF05766.11 Bacteriophage Lambda NinG protein 1.8E-06 78-135 / 73-135
PF14279.5 HNH endonuclease 5.4E-06 94-136 / 1-45
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 1.7E-05 91-137 / 253-297
PF13391.5 HNH endonuclease 1.6E-05 94-135 / 1-44
PF06147.10 Protein of unknown function (DUF968) 3.6E-05 90-135 / 126-173
PF16784.4 Putative HNHc nuclease 0.0016 89-135 / 121-170

Annotations of the NCBI proteins of this PHROG


2:HNH endonuclease 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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