phrog_22963 is made of 3 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
383.33 421 373


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p409244 no NCBI prot ID no annotation VI_04036 Thermococci_gi_295698802 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
A3_VLP_circ_p31 YP_003707131.1 hypothetical protein A3_VLP_circ Methanococcus voltae A3 (unknown) Viruses; unclassified archaeal viruses.
NC_009597_p21 YP_001294072.1 hypothetical protein NC_009597 Pyrococcus abyssi virus 1 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_29394 2 no annotation unknown function 1 3.70E-11 1.55

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10255 kinase other 91.1 0.04 37-58 / 3-24
phrog_11838 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 93.0 0.014 6-58 / 16-63
phrog_124 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 95.9 0.00021 29-64 / 8-44
phrog_14322 no annotation unknown function 92.9 0.014 36-58 / 195-217
phrog_14719 no annotation unknown function 91.1 0.041 14-58 / 271-315
phrog_168 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 95.3 0.00079 34-78 / 37-79
phrog_170 PhoH-like phosphate starvation-inducible other 93.8 0.0068 35-62 / 50-77
phrog_1815 guanylate kinase other 91.6 0.032 38-58 / 5-25
phrog_197 Zot-like toxin moron, auxiliary metabolic gene and host takeover 95.2 0.00099 189-253 / 82-143
phrog_19 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 93.6 0.008 35-60 / 197-222
phrog_2071 ATPase other 96.3 6E-05 38-153 / 6-128
phrog_2107 thymidylate kinase other 92.9 0.015 36-59 / 4-27
phrog_2392 ABC transporter moron, auxiliary metabolic gene and host takeover 94.0 0.0057 33-74 / 367-408
phrog_243 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 93.2 0.011 37-58 / 37-58
phrog_26606 no annotation unknown function 90.9 0.045 39-58 / 136-155
phrog_2666 terminase large subunit head and packaging 93.1 0.012 186-270 / 114-193
phrog_2872 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 90.0 0.064 35-72 / 2-43
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 95.6 0.00041 35-66 / 38-70
phrog_296 DNA transposition protein integration and excision 93.9 0.0062 23-58 / 80-114
phrog_325 Dda-like helicase DNA, RNA and nucleotide metabolism 93.5 0.0088 34-60 / 24-50
phrog_33861 no annotation unknown function 91.3 0.038 33-81 / 187-224
phrog_3757 no annotation unknown function 93.4 0.0094 33-58 / 124-149
phrog_4581 terminase small subunit head and packaging 91.8 0.029 38-55 / 124-141
phrog_50 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 94.6 0.0026 33-63 / 109-139
phrog_5484 DnaA-like replication initiation protein DNA, RNA and nucleotide metabolism 92.7 0.016 33-58 / 25-50
phrog_5836 no annotation unknown function 92.1 0.024 188-254 / 299-357
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 93.7 0.0072 37-63 / 40-66
phrog_6012 DNA helicase DNA, RNA and nucleotide metabolism 90.8 0.046 35-65 / 140-171
phrog_6891 ATPase other 94.7 0.0025 37-68 / 36-66
phrog_7485 no annotation unknown function 94.7 0.0024 37-58 / 229-250
phrog_7507 no annotation unknown function 92.0 0.026 38-59 / 26-47
phrog_761 thymidylate kinase other 93.8 0.0066 35-62 / 2-29
phrog_77 SbcC-like subunit of palindrome specific endonuclease DNA, RNA and nucleotide metabolism 90.0 0.063 30-58 / 23-50
phrog_7998 no annotation unknown function 92.0 0.025 37-67 / 40-72
phrog_800 terminase small subunit head and packaging 94.1 0.0051 35-58 / 8-31
phrog_9172 no annotation unknown function 94.4 0.0035 21-58 / 85-120
phrog_97 UvsX-like recombinase other 90.1 0.063 35-68 / 56-91

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF07693.13 KAP family P-loop domain 1.1E-06 34-62 / 29-57
PF10923.7 P-loop Domain of unknown function (DUF2791) 1.2E-06 8-70 / 21-83
PF06745.12 KaiC 2.7E-06 33-71 / 16-54
PF05673.12 Protein of unknown function (DUF815) 3.9E-06 35-60 / 53-78
PF05729.11 NACHT domain 4.3E-06 38-61 / 2-25
PF02456.14 Adenovirus IVa2 protein 8.4E-06 38-71 / 82-117
PF04665.11 Poxvirus A32 protein 1.4E-05 34-62 / 11-39
PF14516.5 AAA-like domain 1.9E-05 35-62 / 29-56
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 3.2E-05 35-59 / 44-68
PF00308.17 Bacterial dnaA protein 3.7E-05 36-61 / 33-58
PF03266.14 NTPase 4E-05 39-62 / 2-25
PF13401.5 AAA domain 4.8E-05 35-61 / 4-30
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 7.9E-05 33-61 / 11-39
PF12775.6 P-loop containing dynein motor region D3 9.3E-05 34-61 / 31-58
PF00158.25 Sigma-54 interaction domain 0.00013 35-60 / 21-46
PF01078.20 Magnesium chelatase, subunit ChlI 0.00015 35-61 / 21-47
PF05707.11 Zonular occludens toxin (Zot) 0.00017 38-56 / 2-20
PF13191.5 AAA ATPase domain 0.00021 16-64 / 4-52
PF07088.10 GvpD gas vesicle protein 0.00025 34-70 / 8-43
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 0.00034 39-58 / 1-20
PF01637.17 ATPase domain predominantly from Archaea 0.00036 16-62 / 3-46
PF03969.15 AFG1-like ATPase 0.00042 35-60 / 66-91
PF07724.13 AAA domain (Cdc48 subfamily) 0.00047 36-61 / 3-28
PF00625.20 Guanylate kinase 0.00086 36-60 / 2-26
PF03976.13 Polyphosphate kinase 2 (PPK2) 0.001 34-62 / 26-54
PF07931.11 Chloramphenicol phosphotransferase-like protein 0.0014 37-60 / 2-25
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 0.0015 38-70 / 2-34
PF00488.20 MutS domain V 0.0018 39-60 / 1-22
PF00485.17 Phosphoribulokinase / Uridine kinase family 0.0019 38-62 / 1-25
PF13173.5 AAA domain 0.0019 36-59 / 2-25
PF13671.5 AAA domain 0.002 38-59 / 1-22
PF13521.5 AAA domain 0.0023 39-59 / 2-22
PF06414.11 Zeta toxin 0.0023 34-60 / 12-38
PF00265.17 Thymidine kinase 0.0024 36-68 / 1-33
PF05621.10 Bacterial TniB protein 0.0028 37-60 / 39-62
PF01745.15 Isopentenyl transferase 0.0029 37-60 / 2-25
PF10649.8 Protein of unknown function (DUF2478) 0.0034 39-62 / 1-24
PF13238.5 AAA domain 0.0035 39-60 / 1-22
PF10443.8 RNA12 protein 0.0035 34-60 / 15-42
PF00931.21 NB-ARC domain 0.0037 34-60 / 18-44
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.0039 36-62 / 4-30
PF13189.5 Cytidylate kinase-like family 0.0039 38-60 / 1-23
PF01121.19 Dephospho-CoA kinase 0.004 38-59 / 2-23
PF01591.17 6-phosphofructo-2-kinase 0.004 35-60 / 8-33
PF01712.18 Deoxynucleoside kinase 0.0043 39-60 / 1-22
PF03796.14 DnaB-like helicase C terminal domain 0.0044 33-71 / 16-55
PF04851.14 Type III restriction enzyme, res subunit 0.0046 35-61 / 22-48
PF00910.21 RNA helicase 0.0049 39-60 / 1-22
PF08433.9 Chromatin associated protein KTI12 0.0051 37-61 / 2-26
PF09820.8 Predicted AAA-ATPase 0.0051 36-61 / 31-56
PF08303.10 tRNA ligase kinase domain 0.0051 38-59 / 1-22
PF01695.16 IstB-like ATP binding protein 0.0051 34-62 / 46-74
PF06068.12 TIP49 C-terminus 0.0057 15-61 / 27-75
PF11602.7 ATPase P4 of dsRNA bacteriophage phi-12 0.0059 33-68 / 119-154
PF13476.5 AAA domain 0.006 37-59 / 21-43
PF05272.10 Virulence-associated protein E 0.0062 34-60 / 57-83
PF08423.10 Rad51 0.0063 33-62 / 34-63
PF14532.5 Sigma-54 interaction domain 0.0063 35-59 / 20-44
PF00154.20 recA bacterial DNA recombination protein 0.0064 33-70 / 49-86
PF03215.14 Rad17 cell cycle checkpoint protein 0.0071 35-60 / 44-69
PF13177.5 DNA polymerase III, delta subunit 0.0076 35-61 / 18-44
PF10236.8 Mitochondrial ribosomal death-associated protein 3 0.0076 34-63 / 22-51
PF02223.16 Thymidylate kinase 0.0075 41-60 / 1-20
PF16813.4 CRISPR-associated protein Csn2 subfamily St 0.0078 33-63 / 12-42

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004797 thymidine kinase activity
GO:0009058 biosynthetic process
GO:0000155 phosphorelay sensor kinase activity
GO:0005524 ATP binding
GO:0030983 mismatched DNA binding
GO:0006298 mismatch repair
GO:0003697 single-stranded DNA binding
GO:0006281 DNA repair
GO:0008152 metabolic process
GO:0016301 kinase activity
GO:0003723 RNA binding
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0019073 viral DNA genome packaging
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0043752 adenosylcobinamide kinase activity
GO:0004673 protein histidine kinase activity
GO:0003972 RNA ligase (ATP) activity
GO:0004161 dimethylallyltranstransferase activity
GO:0003873 6-phosphofructo-2-kinase activity
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0003678 DNA helicase activity
GO:0006260 DNA replication
GO:0051188 cofactor biosynthetic process
GO:0019072 viral genome packaging
GO:0003724 RNA helicase activity
GO:0016020 membrane
GO:0043531 ADP binding
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0000160 phosphorelay signal transduction system
GO:0008134 transcription factor binding
GO:0009236 cobalamin biosynthetic process
GO:0004140 dephospho-CoA kinase activity
GO:0000166 nucleotide binding
GO:0006000 fructose metabolic process
GO:0016740 transferase activity
GO:0015937 coenzyme A biosynthetic process
GO:0006355 regulation of transcription, DNA-templated

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