phrog_23251 is made of 3 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
142 145 142


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF979560_p264 ATS93664.1 putative HNH homing endonuclease MF979560 Pectobacterium phage DU_PP_I Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Certrevirus; unclassified Certrevirus.
MF979563_p265 ATS93981.1 putative HNH homing endonuclease MF979563 Pectobacterium phage DU_PP_IV Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Certrevirus; unclassified Certrevirus.
MG646671_p20 AUM59367.1 HNH homing endonuclease MG646671 Salmonella phage BPS17S6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus; unclassified Felixounavirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3330 43 no annotation unknown function 2 2.03E-12 2.81
phrog_17517 5 tail protein tail 2 1.65E-15 5.91
phrog_30062 2 no annotation unknown function 1 3.70E-11 1.55

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 93.5 0.0088 28-81 / 97-149
phrog_24671 integrase integration and excision 96.2 0.0001 95-126 / 24-56
phrog_25572 no annotation unknown function 93.5 0.0089 33-80 / 7-39
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 97.4 4.7E-07 13-81 / 11-79
phrog_3593 HNH endonuclease DNA, RNA and nucleotide metabolism 97.7 8.7E-08 11-89 / 31-114
phrog_4234 HNH endonuclease DNA, RNA and nucleotide metabolism 92.5 0.019 8-120 / 2-114
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 91.7 0.03 26-82 / 17-68

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05315.10 ICEA Protein 6.3E-08 22-88 / 80-150
PF13395.5 HNH endonuclease 1.1E-07 38-87 / 1-50
PF05766.11 Bacteriophage Lambda NinG protein 1.2E-07 31-89 / 82-137
PF01844.22 HNH endonuclease 2.2E-07 38-86 / 1-46
PF14279.5 HNH endonuclease 5.6E-07 38-88 / 1-45
PF13391.5 HNH endonuclease 8.4E-06 38-87 / 1-44
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 5.9E-05 35-88 / 253-296
PF06147.10 Protein of unknown function (DUF968) 6.5E-05 34-88 / 126-174
PF16784.4 Putative HNHc nuclease 0.0006 34-88 / 122-171

Annotations of the NCBI proteins of this PHROG


3:HNH homing endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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