phrog_23285 is made of 3 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
200 204 203


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_019526_p12 YP_007007167.1 hypothetical protein NC_019526 Enterobacteria phage vB_KleM-RaK2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Alcyoneusvirus; Klebsiella virus RaK2.
NC_025447_p506 YP_009102100.1 HNH endonuclease NC_025447 Escherichia phage 121Q Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Asteriusvirus; Escherichia virus 121Q.
NC_027364_p59 YP_009150373.1 hypothetical protein NC_027364 Escherichia phage PBECO 4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Asteriusvirus; Escherichia virus PBECO4.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2425 61 no annotation unknown function 3 2.86E-16 6.66
phrog_6343 19 no annotation unknown function 2 1.60E-13 3.92

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 92.2 0.023 48-127 / 101-156
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 93.0 0.013 47-124 / 15-64
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00039 90-126 / 96-132
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 92.7 0.016 49-137 / 17-85
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 97.0 4.5E-06 88-143 / 44-97
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 97.6 1.2E-07 39-131 / 80-167
phrog_25420 HNH endonuclease DNA, RNA and nucleotide metabolism 97.5 2E-07 88-165 / 71-156
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 1E-06 46-143 / 8-89
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 91.4 0.035 90-128 / 49-87
phrog_35175 HNH endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0055 48-132 / 44-124
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 96.5 3.3E-05 87-124 / 17-54
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 90.6 0.05 80-143 / 70-123
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 94.3 0.0038 88-125 / 119-156
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 92.4 0.02 32-125 / 91-168

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 2.7E-08 90-184 / 263-327
PF05766.11 Bacteriophage Lambda NinG protein 7.4E-08 90-145 / 100-157
PF13395.5 HNH endonuclease 1.9E-07 90-124 / 17-51
PF05315.10 ICEA Protein 5.6E-07 40-124 / 84-150
PF01844.22 HNH endonuclease 5.3E-07 91-122 / 12-46
PF14279.5 HNH endonuclease 6.3E-07 90-125 / 12-46
PF06147.10 Protein of unknown function (DUF968) 3.9E-06 91-124 / 138-174
PF13391.5 HNH endonuclease 5.9E-06 90-124 / 11-45
PF16784.4 Putative HNHc nuclease 0.0056 91-124 / 133-171

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein 1:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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