phrog_2338 is made of 64 protein sequences and is annotated as "endolysin"
Functional category: lysis


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
347.84 594 357


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF001361_p94 ASZ77469.1 putative muramidase MF001361 Enterococcus phage EF5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY549443_p93 APZ82020.1 putative N-acetylmuramoyl-L-alanine amidase KY549443 Enterococcus phage EFP01 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Brockvirinae; Schiekvirus; Enterococcus virus EFP01.
MF001358_p56 ASZ76722.1 putative muramidase MF001358 Enterococcus phage EF1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_029009_p116 YP_009218316.1 putative N-acetylmuramoyl-L-alanine amidase NC_029009 Enterococcus phage EFDG1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Brockvirinae; Schiekvirus; Enterococcus virus EFDG1.
p329135 no NCBI prot ID no annotation VI_00404 Bacilli_gi_238801489_3326471_3348798 Viruses.
KY963370_p17 ARW58466.1 N-acetylmuramoyl-L-alanine amidase KY963370 Bacillus phage Negev_SA Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
KX190835_p42 ANT40136.1 N-acetylmuramoyl-L-alanine amidase KX190835 Bacillus phage vB_BtS_BMBtp15 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p211017 no NCBI prot ID no annotation VI_00698 Bacilli_gi_507028670 Viruses.
NC_004820_p65 NP_852545.1 N-acetylmuramoyl-L-alanine amidase NC_004820 Bacillus phage phBC6A51 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p12737 no NCBI prot ID no annotation VI_00425 Bacilli_gi_423502290 Viruses.
NC_028982_p114 YP_009215894.1 N-acetylmuramoyl-L-alanine amidase NC_028982 Bacillus phage JL Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Siminovitchvirus.
p76802 no NCBI prot ID no annotation VI_00691 Bacilli_gi_507027929 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cecivirus; Bacillus virus IEBH.
KY963371_p18 ARW58523.1 N-acetylmuramoyl-L-alanine amidase KY963371 Bacillus phage Carmel_SA Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
NC_028748_p23 YP_009193999.2 N-acetylmuramoyl-L-alanine amidase NC_028748 Bacillus phage vB_BtS_BMBtp3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p61675 no NCBI prot ID no annotation VI_00738 Bacilli_gi_384183548 Viruses.
p12706 no NCBI prot ID no annotation VI_00424 Bacilli_gi_423496617 Viruses.
NC_025423_p44 YP_009099088.1 putative amidase NC_025423 Bacillus phage CP-51 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Siminovitchvirus.
p63004 no NCBI prot ID no annotation VI_00411 Bacilli_gi_423399602_2939316_2990500 Viruses.
NC_001884_p26 NP_046578.1 N-acetylmuramoyl-L-alanine amidase NC_001884 Bacillus virus SPbeta Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Spbetavirus.
p128506 no NCBI prot ID no annotation VI_00701 Bacilli_gi_507039007 Viruses.
p79408 no NCBI prot ID no annotation VI_04404 Bacilli_gi_196042459_4851_52747 Viruses.
p383093 no NCBI prot ID no annotation VI_00426 Bacilli_gi_423508375 Viruses.
p35863 no NCBI prot ID no annotation VI_00416 Bacilli_gi_423422311_2192763_2255576 Viruses.
p35168 no NCBI prot ID no annotation VI_00711 Bacilli_gi_507055493_2793767_2856861 Viruses.
p54890 no NCBI prot ID no annotation VI_00741 Bacilli_gi_407708681 Viruses.
p152439 no NCBI prot ID no annotation VI_00436 Bacilli_gi_423584588_368833_409419 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p58498 no NCBI prot ID no annotation VI_00734 Bacilli_gi_221316922 Viruses.
KX227759_p39 ANT40327.1 N-acetylmuramoyl-L-alanine amidase KX227759 Bacillus phage PfIS075 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cecivirus; unclassified Cecivirus.
KY030782_p17 APD21160.1 N-acetylmuramoyl-L-alanine amidase KY030782 Bacillus phage phi3T Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Spbetavirus; unclassified Spbetavirus.
KT852578_p21 ALJ98013.1 N-acetylmuramoyl-L-alanine amidase KT852578 Bacillus phage BMBtp1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p38580 no NCBI prot ID no annotation VI_00405 Bacilli_gi_423364338 Viruses.
p162439 no NCBI prot ID no annotation VI_00743 Bacilli_gi_452202137 Viruses.
KY963369_p19 ARW58406.1 N-acetylmuramoyl-L-alanine amidase KY963369 Bacillus phage Tavor_SA Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
KT372714_p18 ALF01604.1 N-acetylmuramoyl-L-alanine amidase KT372714 Bacillus phage vB_BtS_BMBtp16 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p36953 no NCBI prot ID no annotation VI_00613 Bacilli_gi_505484080 Viruses.
NC_029008_p20 YP_009218153.1 N-acetylmuramoyl-L-alanine amidase NC_029008 Bacillus phage phi4J1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p132542 no NCBI prot ID no annotation VI_00702 Bacilli_gi_507040157_159148_201524 Viruses; unclassified bacterial viruses.
p53608 no NCBI prot ID no annotation VI_00422 Bacilli_gi_423490892 Viruses.
p78699 no NCBI prot ID no annotation VI_00736 Bacilli_gi_375287510 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cecivirus; Bacillus virus IEBH.
p74535 no NCBI prot ID no annotation VI_00864 Bacilli_gi_514340857 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cecivirus; Bacillus virus IEBH.
p124249 no NCBI prot ID no annotation VI_00690 Bacilli_gi_507027448_46096_89013 Viruses.
p12636 no NCBI prot ID no annotation VI_00424 Bacilli_gi_423496617 Viruses.
p43116 no NCBI prot ID no annotation VI_00473 Bacilli_gi_397738323 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Spbetavirus; Bacillus virus SPbeta.
NC_028983_p116 YP_009216114.1 N-acetylmuramoyl-L-alanine amidase NC_028983 Bacillus phage Shanette Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Siminovitchvirus.
NC_009760_p138 YP_001429728.1 Gram-positive endolysin NC_009760 Bacillus phage 0305phi8-36 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p293796 no NCBI prot ID no annotation VI_00683 Bacilli_gi_505870677 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p182461 no NCBI prot ID no annotation VI_04528 Bacilli_gi_416143743 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p286044 no NCBI prot ID no annotation VI_00932 Bacilli_gi_522836732 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p237420 no NCBI prot ID no annotation VI_06093 Clostridia_gi_545037542_3677_36763 Viruses.
p341050 no NCBI prot ID no annotation VI_04430 Bacilli_gi_294614749 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p221001 no NCBI prot ID no annotation VI_05255 Bacilli_gi_476525634_6267_41028 Viruses.
p409784 no NCBI prot ID no annotation VI_05074 Bacilli_gi_484009374 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p171396 no NCBI prot ID no annotation VI_00570 Bacilli_gi_501614103 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p409814 no NCBI prot ID no annotation VI_05075 Bacilli_gi_484009620 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p235224 no NCBI prot ID no annotation VI_04856 Bacilli_gi_484086219_17820_51091 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p233333 no NCBI prot ID no annotation VI_00719 Bacilli_gi_505865337_25600_59139 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p275383 no NCBI prot ID no annotation VI_00552 Bacilli_gi_501163551 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p282376 no NCBI prot ID no annotation VI_04428 Bacilli_gi_293570856 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p193664 no NCBI prot ID no annotation VI_00681 Bacilli_gi_505812665_525579_562476 Viruses.
p380047 no NCBI prot ID no annotation VI_05257 Bacilli_gi_544676481 Viruses.
p346927 no NCBI prot ID no annotation VI_04483 Bacilli_gi_289566803 Viruses.
p268029 no NCBI prot ID no annotation VI_04429 Bacilli_gi_293572592 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p350596 no NCBI prot ID no annotation VI_04431 Bacilli_gi_294616019 Viruses.
p409789 no NCBI prot ID no annotation VI_04837 Bacilli_gi_484068245 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_881 163 holin lysis 15 8.97E-44 34.17
phrog_199 534 holin lysis 15 2.62E-35 25.7
phrog_1299 115 holin lysis 13 8.66E-40 30.18
phrog_297 414 holin lysis 6 2.55E-14 4.72
phrog_2429 61 involved in bacteriocin production or immunity moron, auxiliary metabolic gene and host takeover 6 2.91E-20 10.66
phrog_12246 8 no annotation unknown function 4 4.46E-19 9.47
phrog_6203 20 no annotation unknown function 3 4.13E-13 3.51
phrog_13357 7 no annotation unknown function 2 3.16E-11 1.62
phrog_13973 7 no annotation unknown function 2 3.16E-11 1.62
phrog_32303 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1110 endolysin lysis 99.9 2.2E-30 28-193 / 4-176
phrog_12609 endolysin lysis 98.1 5.3E-09 46-191 / 20-180
phrog_14048 endolysin lysis 98.2 1.1E-09 28-199 / 9-183
phrog_1493 endolysin lysis 99.7 1.3E-20 41-190 / 19-162
phrog_15001 endolysin lysis 99.4 7.9E-17 44-190 / 18-173
phrog_16339 no annotation unknown function 100.0 2.9E-40 272-355 / 1-84
phrog_1794 amidase lysis 98.5 1.3E-10 212-275 / 245-306
phrog_18955 no annotation unknown function 98.6 4.3E-11 27-162 / 265-406
phrog_19265 no annotation unknown function 99.1 3.1E-14 38-172 / 10-134
phrog_20388 endolysin lysis 94.4 0.0033 74-190 / 231-360
phrog_28089 endolysin lysis 95.7 0.00038 38-157 / 222-370
phrog_2998 endolysin lysis 97.3 7.8E-07 41-190 / 44-202
phrog_3088 amidase lysis 100.0 7.4E-36 25-190 / 1-160
phrog_33549 no annotation unknown function 98.3 5.6E-10 42-135 / 3-101
phrog_3393 endolysin lysis 99.9 1.5E-26 40-333 / 15-288
phrog_4018 amidase lysis 97.4 3.8E-07 36-163 / 19-140
phrog_5182 endolysin lysis 99.7 2.3E-21 25-193 / 3-182
phrog_635 endolysin lysis 99.2 3.6E-15 40-194 / 183-353
phrog_6523 endolysin lysis 98.6 4.9E-11 110-269 / 84-235
phrog_670 endolysin lysis 99.9 7.2E-27 39-193 / 5-161
phrog_700 endolysin lysis 96.7 1.5E-05 45-193 / 190-356
phrog_7470 amidase lysis 92.1 0.024 46-162 / 361-480
phrog_7698 endolysin lysis 99.1 4.9E-14 42-206 / 19-173
phrog_8164 endolysin lysis 99.9 6.2E-27 45-193 / 20-174
phrog_822 amidase lysis 96.3 7.3E-05 46-175 / 10-144
phrog_833 endolysin lysis 100.0 5.8E-38 33-196 / 15-187
phrog_880 endolysin lysis 97.1 2.8E-06 44-193 / 172-338
phrog_9611 endolysin lysis 99.9 5.3E-31 28-191 / 3-170

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01510.24 N-acetylmuramoyl-L-alanine amidase 3.1E-15 47-167 / 4-130
PF06347.12 Bacterial SH3 domain 0.0075 413-476 / 6-54

Annotations of the NCBI proteins of this PHROG


16:N-acetylmuramoyl-L-alanine amidase 2:muramidase 1:Gram-positive endolysin 1:amidase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K01447 E3.5.1.28A, cwlA, xlyA, xlyB : N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] no pathways 699 31

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0009253 peptidoglycan catabolic process
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity

Loading in process