phrog_2391 is made of 62 protein sequences and is annotated as "DNA binding protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
110.65 134 115


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p119266 no NCBI prot ID no annotation VI_03293 Gammaproteobacteria_gi_556366593_2983700_3027266 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p51938 no NCBI prot ID no annotation VI_03227 Gammaproteobacteria_gi_554496818_24732_80798 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p168215 no NCBI prot ID no annotation VI_07354 Gammaproteobacteria_gi_485452988 Viruses.
p84553 no NCBI prot ID no annotation VI_02711 Gammaproteobacteria_gi_423123309_1034864_1082210 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY271399_p11 ARB15720.1 hypothetical protein KY271399 Klebsiella phage 5 LV-2017 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p42342 no NCBI prot ID no annotation VI_03665 Gammaproteobacteria_gi_507091347_2161232_2221557 Viruses.
p45972 no NCBI prot ID no annotation VI_03299 Gammaproteobacteria_gi_556422501_3214257_3273495 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p127797 no NCBI prot ID no annotation VI_03659 Gammaproteobacteria_gi_507080321_2524261_2566866 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p65810 no NCBI prot ID no annotation VI_03806 Gammaproteobacteria_gi_378987404_2728739_2778927 Viruses.
p64184 no NCBI prot ID no annotation VI_03812 Gammaproteobacteria_gi_482902549_1941706_1992396 Viruses.
p173724 no NCBI prot ID no annotation VI_07610 Gammaproteobacteria_gi_418775825 Viruses; unclassified bacterial viruses; Phage Gifsy-1.
NC_010393_p14 YP_001700657.1 hypothetical protein NC_010393 Phage Gifsy-2 Viruses; unclassified viruses; unclassified bacterial viruses.
p404885 no NCBI prot ID no annotation VI_07606 Gammaproteobacteria_gi_418767802 Viruses; unclassified bacterial viruses.
p79987 no NCBI prot ID no annotation VI_09767 Gammaproteobacteria_gi_459806388_644735_692549 Viruses.
p110817 no NCBI prot ID no annotation VI_09916 Gammaproteobacteria_gi_554681077 Viruses.
p80418 no NCBI prot ID no annotation VI_08301 Gammaproteobacteria_gi_452722248_54203_101991 Viruses; unclassified bacterial viruses.
p136724 no NCBI prot ID no annotation VI_10104 Gammaproteobacteria_gi_555286962_793_42879 Viruses.
p434233 no NCBI prot ID no annotation VI_09909 Gammaproteobacteria_gi_554670426 Viruses; unclassified bacterial viruses; Phage Gifsy-2.
p133469 no NCBI prot ID no annotation VI_11357 Gammaproteobacteria_gi_560997440_713275_755579 Viruses.
p280717 no NCBI prot ID no annotation VI_11979 Gammaproteobacteria_gi_565893145 Viruses; unclassified bacterial viruses; Phage Gifsy-2.
p434197 no NCBI prot ID no annotation VI_07628 Gammaproteobacteria_gi_418815745 Viruses; unclassified bacterial viruses; Phage Gifsy-2.
p224755 no NCBI prot ID no annotation VI_07667 Gammaproteobacteria_gi_445154918 Viruses; unclassified bacterial viruses.
p360347 no NCBI prot ID no annotation VI_09953 Gammaproteobacteria_gi_554959014 Viruses.
p366667 no NCBI prot ID no annotation VI_06440 Gammaproteobacteria_gi_153901837_0_17924 Viruses.
NC_010392_p45 YP_001700630.1 hypothetical protein NC_010392 Phage Gifsy-1 Viruses; unclassified viruses; unclassified bacterial viruses.
p142721 no NCBI prot ID no annotation VI_10108 Gammaproteobacteria_gi_555287500_25_41570 Viruses.
p426220 no NCBI prot ID no annotation VI_09962 Gammaproteobacteria_gi_554964600 Viruses.
p150836 no NCBI prot ID no annotation VI_11870 Gammaproteobacteria_gi_554640811_1264_42009 Viruses.
p94037 no NCBI prot ID no annotation VI_07620 Gammaproteobacteria_gi_418804976_66_45852 Viruses.
p395904 no NCBI prot ID no annotation VI_11399 Gammaproteobacteria_gi_544851018 Viruses.
p133371 no NCBI prot ID no annotation VI_03648 Gammaproteobacteria_gi_525855729_2068849_2111153 Viruses.
p116453 no NCBI prot ID no annotation VI_11855 Gammaproteobacteria_gi_553855939_387631_431490 Viruses.
p372414 no NCBI prot ID no annotation VI_10084 Gammaproteobacteria_gi_555271326 Viruses.
p428752 no NCBI prot ID no annotation VI_06435 Gammaproteobacteria_gi_149113312 Viruses; unclassified bacterial viruses.
p306522 no NCBI prot ID no annotation VI_10049 Gammaproteobacteria_gi_555254823_70945_96001 Viruses.
p235985 no NCBI prot ID no annotation VI_10093 Gammaproteobacteria_gi_555281271 Viruses.
p66063 no NCBI prot ID no annotation VI_03567 Gammaproteobacteria_gi_526218030_4016064_4066234 Viruses.
p352455 no NCBI prot ID no annotation VI_10082 Gammaproteobacteria_gi_555270637 Viruses.
p395339 no NCBI prot ID no annotation VI_10016 Gammaproteobacteria_gi_555241746 Viruses; unclassified bacterial viruses.
p336618 no NCBI prot ID no annotation VI_08377 Gammaproteobacteria_gi_452722454_0_21528 Viruses.
p118123 no NCBI prot ID no annotation VI_09046 Gammaproteobacteria_gi_452725193_0_43674 Viruses.
p377571 no NCBI prot ID no annotation VI_10076 Gammaproteobacteria_gi_555268629 Viruses.
p79795 no NCBI prot ID no annotation VI_03805 Gammaproteobacteria_gi_378982542_2724401_2772242 Viruses.
p88125 no NCBI prot ID no annotation VI_10103 Gammaproteobacteria_gi_555286310 Viruses.
p125086 no NCBI prot ID no annotation VI_03560 Gammaproteobacteria_gi_311277332_1953685_1996496 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p88356 no NCBI prot ID no annotation VI_09347 Gammaproteobacteria_gi_481032972_70963_117603 Viruses.
p139956 no NCBI prot ID no annotation VI_10035 Gammaproteobacteria_gi_555247099_0_41808 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p417998 no NCBI prot ID no annotation VI_11452 Gammaproteobacteria_gi_550693532 Viruses; unclassified bacterial viruses; Phage Gifsy-2.
NC_019545_p52 YP_007011022.1 putative DNA-binding protein NC_019545 Salmonella phage SPN3UB Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p236365 no NCBI prot ID no annotation VI_02402 Gammaproteobacteria_gi_478427106 Viruses; unclassified bacterial viruses.
p296182 no NCBI prot ID no annotation VI_10012 Gammaproteobacteria_gi_555241427_0_26328 Viruses.
p116262 no NCBI prot ID no annotation VI_09045 Gammaproteobacteria_gi_452725145_490_44365 Viruses.
p434218 no NCBI prot ID no annotation VI_07645 Gammaproteobacteria_gi_418837936 Viruses; unclassified bacterial viruses; Phage Gifsy-2.
p386119 no NCBI prot ID no annotation VI_12032 Gammaproteobacteria_gi_188475090_329_15997 Viruses.
p221311 no NCBI prot ID no annotation VI_03226 Gammaproteobacteria_gi_554496810 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p79591 no NCBI prot ID no annotation VI_03291 Gammaproteobacteria_gi_556328063_648589_696455 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p64065 no NCBI prot ID no annotation VI_03018 Gammaproteobacteria_gi_157144296_1746080_1796777 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p298069 no NCBI prot ID no annotation VI_03305 Gammaproteobacteria_gi_556464165_1470019_1496079 Viruses.
p82535 no NCBI prot ID no annotation VI_11829 Gammaproteobacteria_gi_550796365_3490252_3537771 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p124710 no NCBI prot ID no annotation VI_03301 Gammaproteobacteria_gi_556426767_3346990_3389832 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p130928 no NCBI prot ID no annotation VI_03294 Gammaproteobacteria_gi_556398877_1928390_1970793 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p308136 no NCBI prot ID no annotation VI_10109 Gammaproteobacteria_gi_555288815 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_50 1303 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 50 6.76E-111 101.29
phrog_1138 131 no annotation unknown function 15 7.30E-43 33.26
phrog_5585 23 no annotation unknown function 13 3.00E-49 39.64
phrog_4807 28 no annotation unknown function 8 8.50E-29 19.19
phrog_630 224 no annotation unknown function 5 9.22E-13 3.16
phrog_1667 90 no annotation unknown function 4 1.91E-12 2.84
phrog_1033 143 ParB-like partition protein DNA, RNA and nucleotide metabolism 4 2.01E-11 1.82
phrog_19118 4 no annotation unknown function 4 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10100 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.5 0.052 10-47 / 23-60
phrog_12375 DNA binding protein DNA, RNA and nucleotide metabolism 91.0 0.042 28-57 / 24-53
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 92.9 0.014 15-49 / 9-42
phrog_14147 transcriptional regulator transcription regulation 93.2 0.011 7-60 / 5-56
phrog_142 Ren-like exclusion protein moron, auxiliary metabolic gene and host takeover 97.6 1.6E-07 12-66 / 2-56
phrog_151 transposase integration and excision 92.7 0.016 3-55 / 5-52
phrog_2538 terminase small subunit head and packaging 91.7 0.03 25-50 / 18-43
phrog_268 no annotation unknown function 93.8 0.0064 14-62 / 5-52
phrog_2907 excisionase integration and excision 90.4 0.055 26-49 / 5-28
phrog_4715 ParB-like partition protein DNA, RNA and nucleotide metabolism 90.2 0.058 2-51 / 102-171
phrog_6336 no annotation unknown function 91.4 0.035 22-61 / 22-62
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 91.0 0.042 25-50 / 67-92
phrog_66 excisionase and transcriptional regulator integration and excision 94.3 0.0039 24-55 / 7-34

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 1.6E-08 21-88 / 7-89
PF06163.10 Bacterial protein of unknown function (DUF977) 3.9E-08 21-119 / 11-112
PF11313.7 Protein of unknown function (DUF3116) 9.1E-08 25-88 / 10-78
PF14394.5 Domain of unknown function (DUF4423) 2.1E-07 21-88 / 20-88
PF07381.10 Winged helix DNA-binding domain (DUF1495) 2.2E-07 21-88 / 8-87
PF09114.9 Transcription factor MotA, activation domain 2.5E-07 19-88 / 13-77
PF02334.15 Replication terminator protein 2.6E-07 25-88 / 21-99
PF01638.16 HxlR-like helix-turn-helix 3E-07 25-104 / 8-84
PF14557.5 Putative AphA-like transcriptional regulator 3.2E-07 33-88 / 22-86
PF04079.15 Segregation and condensation complex subunit ScpB 4.5E-07 19-88 / 80-148
PF13601.5 Winged helix DNA-binding domain 5.4E-07 26-88 / 4-68
PF01090.18 Ribosomal protein S19e 6.6E-07 26-88 / 55-131
PF10711.8 Hypothetical protein (DUF2513) 6.9E-07 24-88 / 7-81
PF14277.5 Domain of unknown function (DUF4364) 7.7E-07 26-88 / 4-69
PF05584.10 Sulfolobus plasmid regulatory protein 8.1E-07 27-86 / 10-69
PF03551.13 Transcriptional regulator PadR-like family 8.4E-07 34-88 / 12-71
PF02319.19 E2F/DP family winged-helix DNA-binding domain 8.7E-07 25-70 / 10-57
PF13463.5 Winged helix DNA-binding domain 1E-06 25-84 / 6-66
PF14947.5 Winged helix-turn-helix 1.5E-06 26-88 / 6-67
PF09639.9 YjcQ protein 1.6E-06 35-88 / 15-79
PF12793.6 Sugar transport-related sRNA regulator N-term 1.7E-06 26-88 / 6-71
PF04492.12 Bacteriophage replication protein O 2.1E-06 20-70 / 25-83
PF03965.15 Penicillinase repressor 2.2E-06 24-85 / 5-70
PF02002.16 TFIIE alpha subunit 3E-06 23-88 / 13-80
PF08222.10 CodY helix-turn-helix domain 3.8E-06 35-70 / 3-38
PF05732.10 Firmicute plasmid replication protein (RepL) 4.2E-06 23-70 / 56-109
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 4.8E-06 21-69 / 12-60
PF09012.9 FeoC like transcriptional regulator 5.3E-06 27-71 / 5-49
PF09202.10 Rio2, N-terminal 7.8E-06 35-88 / 23-73
PF16221.4 winged helix-turn-helix 1E-05 23-68 / 32-78
PF01978.18 Sugar-specific transcriptional regulator TrmB 1.3E-05 25-71 / 11-57
PF02295.16 Adenosine deaminase z-alpha domain 1.3E-05 26-70 / 8-53
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 1.4E-05 39-88 / 29-76
PF08784.10 Replication protein A C terminal 1.7E-05 23-70 / 41-95
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 1.9E-05 25-71 / 4-53
PF01475.18 Ferric uptake regulator family 1.9E-05 22-71 / 7-62
PF03428.12 Replication protein C N-terminal domain 2E-05 37-86 / 71-122
PF09904.8 Winged helix-turn helix 2E-05 26-68 / 11-53
PF01726.15 LexA DNA binding domain 2.8E-05 36-71 / 25-61
PF08461.9 Ribonuclease R winged-helix domain 2.8E-05 29-87 / 5-63
PF04182.11 B-block binding subunit of TFIIIC 3.1E-05 26-71 / 6-53
PF07848.11 PaaX-like protein 3.2E-05 34-70 / 18-57
PF05158.11 RNA polymerase Rpc34 subunit 3.4E-05 21-71 / 91-143
PF04703.11 FaeA-like protein 3.4E-05 27-70 / 5-48
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 3.5E-05 35-88 / 24-72
PF09824.8 ArsR transcriptional regulator 3.7E-05 20-69 / 15-61
PF06969.15 HemN C-terminal domain 3.7E-05 26-69 / 10-54
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 4.1E-05 34-88 / 22-73
PF10771.8 Winged helix-turn-helix domain (DUF2582) 4.9E-05 22-71 / 8-57
PF12802.6 MarR family 5.2E-05 37-70 / 22-55
PF09339.9 IclR helix-turn-helix domain 5.4E-05 37-69 / 19-51
PF00392.20 Bacterial regulatory proteins, gntR family 5.5E-05 32-70 / 19-58
PF01047.21 MarR family 5.6E-05 27-70 / 8-51
PF01022.19 Bacterial regulatory protein, arsR family 5.6E-05 27-66 / 7-46
PF02082.19 Transcriptional regulator 5.8E-05 37-70 / 25-58
PF12840.6 Helix-turn-helix domain 6.9E-05 23-70 / 9-54
PF13412.5 Winged helix-turn-helix DNA-binding 8.9E-05 28-66 / 9-47
PF16864.4 Dimerisation domain 0.00011 24-88 / 20-78
PF13034.5 Protein of unknown function (DUF3895) 0.00012 24-71 / 5-68
PF03297.14 S25 ribosomal protein 0.00012 27-70 / 47-90
PF08220.11 DeoR-like helix-turn-helix domain 0.00012 27-70 / 5-48
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.00016 35-69 / 16-50
PF08535.9 KorB domain 0.00023 36-88 / 3-58
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.00024 34-70 / 19-55
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00025 38-69 / 13-47
PF15977.4 Winged helix-turn-helix DNA binding 0.00025 36-70 / 23-57
PF01316.20 Arginine repressor, DNA binding domain 0.00035 25-70 / 8-55
PF09182.9 Bacterial purine repressor, N-terminal 0.00038 26-69 / 8-58
PF09397.9 Ftsk gamma domain 0.00042 26-71 / 9-54
PF11972.7 HTH DNA binding domain 0.00042 27-67 / 4-41
PF14338.5 Mrr N-terminal domain 0.00057 47-88 / 48-84
PF13545.5 Crp-like helix-turn-helix domain 0.00066 35-69 / 26-60
PF14502.5 Helix-turn-helix domain 0.00073 35-70 / 5-40
PF07183.10 Protein of unknown function (DUF1403) 0.00086 23-71 / 275-321
PF08279.11 HTH domain 0.00089 34-64 / 13-43
PF07900.10 Protein of unknown function (DUF1670) 0.00096 34-70 / 93-129
PF05331.10 Protein of unknown function (DUF742) 0.001 24-71 / 43-88
PF01418.16 Helix-turn-helix domain, rpiR family 0.0011 36-70 / 34-68
PF05043.12 Mga helix-turn-helix domain 0.0012 23-63 / 17-57
PF17443.1 Uncharacterized protein pXO2-72 0.0015 35-69 / 7-50
PF09756.8 DDRGK domain 0.0018 24-71 / 103-150
PF13404.5 AsnC-type helix-turn-helix domain 0.0021 31-60 / 12-41
PF00325.19 Bacterial regulatory proteins, crp family 0.0023 38-66 / 4-32
PF06971.12 Putative DNA-binding protein N-terminus 0.0033 26-57 / 15-48
PF13730.5 Helix-turn-helix domain 0.0034 38-66 / 28-52
PF07037.10 Putative transcription regulator (DUF1323) 0.0034 38-88 / 2-51
PF09681.9 N-terminal phage replisome organiser (Phage_rep_org_N) 0.0046 37-69 / 54-86
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.0049 38-60 / 53-75
PF09821.8 C-terminal AAA-associated domain 0.0053 41-88 / 2-43
PF16509.4 TrfB plasmid transcriptional repressor 0.0054 35-86 / 30-82
PF08679.10 Dissimilatory sulfite reductase D (DsrD) 0.0061 26-70 / 4-51
PF02954.18 Bacterial regulatory protein, Fis family 0.0081 35-59 / 15-39

Annotations of the NCBI proteins of this PHROG


3:hypothetical protein 1:DNA-binding protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006276 plasmid maintenance
GO:0005524 ATP binding
GO:0005666 DNA-directed RNA polymerase III complex
GO:0043565 sequence-specific DNA binding
GO:0006508 proteolysis
GO:0003735 structural constituent of ribosome
GO:0051775 response to redox state
GO:0003723 RNA binding
GO:0006525 arginine metabolic process
GO:0006412 translation
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0051304 chromosome separation
GO:0006281 DNA repair
GO:0004252 serine-type endopeptidase activity
GO:0003700 DNA binding transcription factor activity
GO:0006274 DNA replication termination
GO:0005840 ribosome
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006468 protein phosphorylation
GO:0004674 protein serine/threonine kinase activity
GO:0006383 transcription by RNA polymerase III
GO:0005622 intracellular
GO:0009289 pilus
GO:0006260 DNA replication
GO:0007131 reciprocal meiotic recombination
GO:0009378 four-way junction helicase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex

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