phrog_24252 is made of 3 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
146 146 146


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_004084_p58 NP_665975.1 putative HNH endonuclease NC_004084 Natrialba phage PhiCh1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus.
p48067 no NCBI prot ID no annotation VI_12205 Halobacteria_gi_448285003 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus; Natrialba phage PhiCh1.
p47368 no NCBI prot ID no annotation VI_03977 Halobacteria_gi_289594273 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus; Natrialba phage PhiCh1.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_4278 32 no annotation unknown function 3 1.97E-17 7.83
phrog_17210 5 no annotation unknown function 3 2.74E-21 11.68

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10822 HNH endonuclease DNA, RNA and nucleotide metabolism 95.5 0.00062 16-69 / 100-146
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0023 5-75 / 21-85
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 95.4 0.00075 7-71 / 139-199
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0019 5-74 / 52-115
phrog_1571 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2.1E-05 14-68 / 20-85
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0019 5-82 / 6-84
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00038 6-86 / 26-91
phrog_2255 HNH endonuclease DNA, RNA and nucleotide metabolism 92.1 0.025 14-72 / 64-127
phrog_24030 RNA ligase DNA, RNA and nucleotide metabolism 91.1 0.04 1-69 / 4-62
phrog_3106 HNH endonuclease DNA, RNA and nucleotide metabolism 93.4 0.0099 14-70 / 43-104
phrog_4581 terminase small subunit head and packaging 93.6 0.0084 5-73 / 52-109
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 94.6 0.0025 4-86 / 12-82
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0054 4-69 / 39-96
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 95.3 0.00093 1-75 / 4-72
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 90.9 0.045 34-74 / 96-136
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2E-06 5-68 / 17-75
phrog_8060 no annotation unknown function 95.6 0.00045 14-75 / 37-85
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 94.4 0.0035 5-68 / 119-183

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05766.11 Bacteriophage Lambda NinG protein 1.2E-11 5-117 / 76-179
PF05315.10 ICEA Protein 9.1E-09 3-72 / 81-150
PF13395.5 HNH endonuclease 4E-08 18-72 / 1-51
PF01844.22 HNH endonuclease 1.8E-07 18-71 / 1-47
PF14279.5 HNH endonuclease 1.9E-07 18-74 / 1-47
PF13391.5 HNH endonuclease 4.5E-06 40-72 / 11-45
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 5.7E-06 15-74 / 253-298
PF06147.10 Protein of unknown function (DUF968) 1.7E-05 14-71 / 126-173
PF16784.4 Putative HNHc nuclease 0.0003 14-74 / 122-173
PF16786.4 Recombination enhancement, RecA-dependent nuclease 0.0064 16-70 / 15-65

Annotations of the NCBI proteins of this PHROG


1:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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